Abstract: A patient-specific tibial pin guide for placement on a tibia during a joint arthroplasty procedure on a patient is disclosed. The tibial pin guide includes a patient-specific inner surface having a first offset portion and a second offset portion. The first offset portion is configured to be offset from and mimic a first bone surface. The first offset portion of the patient-specific inner surface is shaped to form a gap to accommodate soft tissue overlying a proximal surface of the tibia of the patient. The second offset portion of the patient-specific inner surface is shaped to provide clearance for a patella tendon of the patient. The tibial pin guide also has a first patient-specific contact area configured for direct bone registration without intervening soft tissue and a second patient-specific contact area that is configured for direct bone registration without intervening soft tissue. The second patient-specific contact area is non-contiguous with the first patient-specific contact area.

Abstract: A convertible patient-specific guide for use in arthroplasty has a body having a patient-specific three-dimensional undersurface closely mateable engageable in only one position with a corresponding joint surface of a specific patient. The convertible guide includes patient-specific guiding formations extending from the body and configured for guiding both a total arthroplasty of the joint and a partial arthroplasty of the joint, such that the arthroplasty to be performed is intraoperatively changeable.

Abstract: A method of preparing a distal femur for a knee joint implant includes mounting a patient-specific bone engagement surface of a femoral alignment guide on a complementary surface of a distal femur of a patient. A plurality of alignment pins is inserted through a corresponding plurality of guiding bores of the femoral alignment guide into the distal femur. A cutting guide is mounted on first and second alignment pins of the plurality of alignment pins, and a first resection of the distal femur is made using the cutting guide while cutting through the femoral alignment guide.

Abstract: A method of intraoperatively selecting between a partial knee arthroplasty and total knee arthroplasty includes mounting a patient-specific three-dimensional surface of a convertible patient-specific guide in a unique position mating to a corresponding surface of a distal femoral bone. The convertible patient-specific guide includes an anterior portion and a distal portion a patellofemoral guide. One of a total knee arthroplasty and a partial knee arthroplasty is selected intraoperatively. If total knee arthroplasty is selected, first and second covers are removed from corresponding first and second distal guiding bore. First and second distal pins through the first and second distal guiding bores are registered on the bone. If partial knee arthroplasty is selected, the anterior portion is severed and removed along a frangible groove and the distal portion is used as a patellofemoral guide.

Abstract: An instrument set and related method for preparing a proximal tibia during a bi-cruciate retaining procedure are disclosed. The instrument set can include a tibial resection block, a cut guide, and a locking arm. The tibial resection block can be configured to be fixed to an anterior portion of the proximal tibia. The tibial resection block can define a slot that extends in a medial-lateral direction when the tibial resection block is fixed to the proximal tibia. The cut guide can have a body, a medial arm, and a lateral arm. A medial cut slot can be defined between the body and the medial arm. A lateral cut slot can be defined between the body and the lateral arm. The cut guide can further comprise a tongue extending therefrom. The tongue can be configured to be received by and slidably translate along the slot of the tibial resection block.

Abstract: An orthopedic device includes a femoral implant having a non-custom internal bone engagement surface. The femoral implant includes at least nine parameters adjusted preoperatively to correspond to a specific patient. The parameters can include patient-specific lengths, such as, for example, medial and lateral condyle widths and notch height, and patient-specific medial and lateral angles.

Abstract: An orthopedic device includes a drill guide configured to be mounted on a patient-specific alignment guide for intraoperatively confirming alignment of the patient-specific alignment guide relative to a bone. The patient-specific alignment guide includes first and second referencing holes. The drill guide includes a main body with a first coupling member and a second coupling member. The first and second coupling members are configured to be received within the first and second referencing holes, respectively. The first and second coupling members each include corresponding first and second drill openings configured to align with the first and second referencing holes, respectively. The drill openings each guide a drilling tool toward the bone to drill corresponding holes in the bone. The main body also includes an alignment confirmation feature configured for confirming alignment of the patient-specific alignment guide relative to the bone before drilling holes in the bone.

Abstract: A patient-specific tibial pin guide for placement on a tibia during a joint arthroplasty procedure on a patient is disclosed. The tibial pin guide includes a patient-specific inner surface having a first offset portion and a second offset portion. The first offset portion is configured to be offset from and mimic a first bone surface. The first offset portion of the patient-specific inner surface is shaped to form a gap to accommodate soft tissue overlying a proximal surface of the tibia of the patient. The second offset portion of the patient-specific inner surface is shaped to provide clearance for a patella tendon of the patient. The tibial pin guide also has a first patient-specific contact area configured for direct bone registration without intervening soft tissue and a second patient-specific contact area that is configured for direct bone registration without intervening soft tissue. The second patient-specific contact area is non-contiguous with the first patient-specific contact area.

Abstract: An orthopedic device includes a drill guide configured to be mounted on a patient-specific alignment guide for intraoperatively confirming alignment of the patient-specific alignment guide relative to a bone. The patient-specific alignment guide includes first and second referencing holes. The drill guide includes a main body with a first coupling member and a second coupling member. The first and second coupling members are configured to be received within the first and second referencing holes, respectively. The first and second coupling members each include corresponding first and second drill openings configured to align with the first and second referencing holes, respectively. The drill openings each guide a drilling tool toward the bone to drill corresponding holes in the bone. The main body also includes an alignment confirmation feature configured for confirming alignment of the patient-specific alignment guide relative to the bone before drilling holes in the bone.

Abstract: An orthopedic device for joint arthroplasty includes a patient-specific alignment guide constructed and configured for a specific patient from medical scans that show a bone surface of a bone of the patient without any overlying soft tissue. The patient-specific alignment guide includes a patient-specific inner surface configured to be offset from and mimic the bone surface and form a clearance for soft tissue overlying the bone surface. The alignment guide also includes a plurality of patient-specific contact areas configured to mate and register directly on the bone surface without intervening soft tissue for direct bone registration. The plurality of patient-specific contact areas includes non-contiguous surface contact areas.

Abstract: A patient-specific unicompartmental tibial guide has a patient-specific body with an inner surface. The inner surface is preoperatively configured to nestingly conform and mate in only one position with an anterior portion and a proximal portion of a tibial bone of a specific patient. The tibial guide includes a vertical resection channel having a variable width preoperatively configured for guiding a vertical resection through the proximal portion of the tibial bone.

Abstract: A surgical kit for unicompartmental knee arthroplasty includes a unitary patient-specific unicompartmental tibial guide and a tibial drill template and other instruments. The tibial guide has a patient-specific body with an inner surface preoperatively configured to nestingly conform and mate in only one position with an anterior portion and a proximal portion of one compartment of a tibial bone of a specific patient. The tibial guide includes a drill guide portion preoperatively configured for drilling first and second anterior holes into the tibial bone for guiding a horizontal tibial resection. The tibial guide includes a vertical resection guide portion preoperatively configured for guiding a vertical resection through the tibial bone before the horizontal resection.

Abstract: A patient-specific unicompartmental tibial guide has a patient-specific body with an inner surface. The inner surface is preoperatively configured to nestingly conform and mate in only one position with an anterior portion and a proximal portion of a tibial bone of a specific patient. The tibial guide includes a vertical resection channel having a variable width preoperatively configured for guiding a vertical resection through the proximal portion of the tibial bone.

Abstract: A method can include receiving, at a server, preoperative image data of a patient's bone, and accessing, at the server, a database of three-dimensional model data. A patient specific three-dimensional model of the patient's bone can be generated, at the server. A preoperative surgical plan can be generated at the server, which can include comparing aspects of the preoperative surgical plan with predetermined reliability criteria. An interactive user interface for use by a surgeon to review the preoperative surgical plan can be provided, from the server, to a user device. Approval of the preoperative surgical plan can be received, at the server, via the interactive user interface. Postoperative image data of the patient's bone can be received at the server. A postoperative outcome study report can be generated, at the server, and can include a comparison of the preoperative surgical plan with the postoperative image data.

Abstract: A method of intraoperatively selecting between a partial knee arthroplasty and total knee arthroplasty includes mounting a patient-specific three-dimensional surface of a convertible patient-specific guide in a unique position mating to a corresponding surface of a distal femoral bone. The convertible patient-specific guide includes an anterior portion and a distal portion a patellofemoral guide. One of a total knee arthroplasty and a partial knee arthroplasty is selected intraoperatively. If total knee arthroplasty is selected, first and second covers are removed from corresponding first and second distal guiding bore. First and second distal pins through the first and second distal guiding bores are registered on the bone. If partial knee arthroplasty is selected, the anterior portion is severed and removed along a frangible groove and the distal portion is used as a patellofemoral guide.

Abstract: A method of implanting a prosthesis based on bone density of a bone is provided. A first bone density of the bone may be determined at a first portion of the bone. A second bone density of the bone may be determined at a second portion of the bone. A first desired amount of bone removal may be determined at the first portion of the bone based on the first bone density. A second desired amount of bone removal may be determined at the second portion of the bone based on the second bone density. The desired amounts of bone may be removed from the first and second portions of the bone. A prosthesis may be selected and implanted.

Abstract: A method of preparing a distal femur for a knee joint implant includes mounting a patient-specific bone engagement surface of a femoral alignment guide on a complementary surface of a distal femur of a patient. A plurality of alignment pins is inserted through a corresponding plurality of guiding bores of the femoral alignment guide into the distal femur. A cutting guide is mounted on first and second alignment pins of the plurality of alignment pins, and a first resection of the distal femur is made using the cutting guide while cutting through the femoral alignment guide.

Abstract: A convertible patient-specific guide for use in arthroplasty has a body having a patient-specific three-dimensional undersurface closely mateable engageable in only one position with a corresponding joint surface of a specific patient. The convertible guide includes patient-specific guiding formations extending from the body and configured for guiding both a total arthroplasty of the joint and a partial arthroplasty of the joint, such that the arthroplasty to be performed is intraoperatively changeable.

Abstract: A surgical kit for unicompartmental knee arthroplasty includes a unitary patient-specific unicompartmental tibial guide and a tibial drill template and other instruments. The tibial guide has a patient-specific body with an inner surface preoperatively configured to nestingly conform and mate in only one position with an anterior portion and a proximal portion of one compartment of a tibial bone of a specific patient. The tibial guide includes a drill guide portion preoperatively configured for drilling first and second anterior holes into the tibial bone for guiding a horizontal tibial resection. The tibial guide includes a vertical resection guide portion preoperatively configured for guiding a vertical resection through the tibial bone before the horizontal resection.

Abstract: An orthopedic device includes a patient-specific alignment guide operable for preparing a bone of a patient for resection during joint arthroplasty. The alignment guide includes a patient-specific bone engagement surface complementary to a surface of the bone of the patient and imaged from a bone scan of the patient. The alignment guide includes a plurality of guiding bores, and a plurality of alignment pins received through corresponding guiding bores for attaching the alignment guide to the bone. The alignment pins are resorbable and can be cut off during a resection of the bone.