Patents by Inventor Joshua C. Tycko

Joshua C. Tycko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assessing nuclease cleavage
    Patent number: 12286727
    Abstract: The present disclosure relates to systems and methods of analyzing cleavage profiles of nucleases.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: April 29, 2025
    Assignee: Editas Medicine, Inc.
    Inventors: Joshua C. Tycko, Barrett Ethan Steinberg, Nick Huston, Hariharan Jayaram
  • SERINE RECOMBINASES
    Publication number: 20240417754
    Abstract: Provided herein are recombinases and compositions, methods of identification and methods of using thereof.
    Type: Application
    Filed: November 3, 2022
    Publication date: December 19, 2024
    Inventors: Ami S. Bhatt, Matthew G. Durrant, Joshua C. Tycko, Patrick D. Hsu, Alison Fanton, Michael C. Bassik, Lacramioara Bintu
  • ASSESSING NUCLEASE CLEAVAGE
    Publication number: 20200190699
    Abstract: The present disclosure relates to systems and methods of analyzing cleavage profiles of nucleases.
    Type: Application
    Filed: December 19, 2017
    Publication date: June 18, 2020
    Inventors: Joshua C. Tycko, Barrett Ethan Steinberg, Nick Huston, Hariharan Jayaram
  • CRISPR/CAS-RELATED METHODS AND COMPOSITIONS FOR TREATING DUCHENNE MUSCULAR DYSTROPHY
    Publication number: 20190134221
    Abstract: Disclosed herein are vectors that targets a dystrophin gene, encoding at least one Cas9 molecule or a Cas9 fusion protein, and at least one gRNA molecule (e.g., two gRNA molecules), and compositions and cells comprising such vectors. Also provided are methods for using the vectors, compositions and cells for genome engineering (e.g., correcting a mutant dystrophin gene), and for treating DMD.
    Type: Application
    Filed: May 5, 2017
    Publication date: May 9, 2019
    Inventors: David A. Bumcrot, Nicholas C. Huston, Joshua C. Tycko, Jacqueline Robinson-Hamm, Charles A. Gersbach
  • Crispr/Cas-Related Methods and Compositions for Treating Duchenne Muscular Dystrophy and Becker
    Publication number: 20190048337
    Abstract: CRISPR/CAS-related compositions and methods for treatment of DMD, BMD, or DCM type 3B are described.
    Type: Application
    Filed: September 29, 2017
    Publication date: February 14, 2019
    Applicant: EDITAS MEDICINE, INC.
    Inventors: Patrick David Hsu, Morgan Lee Maeder, Penrose Odonnell, Joshua C. Tycko, Nicholas C. Huston