Abstract: A technology is described for multipoint tissue elastic property measurement. An example method (700) 700 includes generating a treatment map (710) of an anatomical region that shows focal points within the anatomical region to be exposed to Focused Ultrasound (FUS) pulses; acquiring a reference MR-ARFI image (720) of the anatomical region containing the focal points using the treatment map; acquiring an active MR-ARFI image (730) for each of the focal points in the anatomical region during exposure of the focal points to the FUS pulses using the treatment map; interleaving the reference MR-ARFI image and active MR-ARFI images (740) to create a combined image of the anatomical region and the focal points; and calculating a tissue displacement measurement (750) for the focal points exposed to the simultaneous and/or rapidly interleaved FUS pulses using the combined image of the anatomical region and the focal points exposed to the simultaneous FUS pulses.