Abstract: An outdoor equipment cover is configured to be utilized with outdoor equipment having a metallic component, the outdoor equipment cover includes a cover body, a magnetic fastener, and a secondary fastener. The cover body presents an outer edge disposed along a bottom side and a cover void therein configured to receive the outdoor equipment therein. The magnetic fastener and the secondary fastener are each secured to the cover body. The magnetic fastener is configured to provide a magnetic force to keep the magnetic fastener selectively secured to the metallic component of the outdoor equipment so as to keep the cover body in place around the outdoor equipment therein. The secondary fastener is configured to reduce a cross-sectional area of the cover void so as to prevent the outdoor equipment cover from being removed from the outdoor equipment while the secondary fastener is emplaced.

Abstract: A grill cover is configured to be utilized with a grill having a metallic component, the grill cover includes a cover body, a magnetic fastener, and a secondary fastener. The cover body presents an outer edge disposed along a bottom side and a cover void therein configured to receive the grill therein. The magnetic fastener and the secondary fastener are each secured to the cover body. The magnetic fastener is configured to provide a magnetic force to keep the magnetic fastener selectively secured to the metallic component of the grill so as to keep the cover body in place around the grill therein. The secondary fastener is configured to reduce a cross-sectional area of the cover void so as to prevent the grill cover from being removed from the grill while the secondary fastener is emplaced.

Abstract: Disclosed herein are systems, methods, and compositions useful for determining cellular pathway disruption comprising the use of RNA expression level information. This determined level of disruption can assist in the identification of genetic variants that alter pathway activity, to correlate these variants with disease state and disease progression, and to identify those therapeutics most likely to be effective and which should be avoided.

Abstract: A grill cover is configured to be utilized with a grill having a metallic component, the grill cover includes a cover body, a magnetic fastener, and a secondary fastener. The cover body presents an outer edge disposed along a bottom side and a cover void therein configured to receive the grill therein. The magnetic fastener and the secondary fastener are each secured to the cover body. The magnetic fastener is configured to provide a magnetic force to keep the magnetic fastener selectively secured to the metallic component of the grill so as to keep the cover body in place around the grill therein. The secondary fastener is configured to reduce a cross-sectional area of the cover void so as to prevent the grill cover from being removed from the grill while the secondary fastener is emplaced.

Abstract: Systems and methods for facilitating virtual space instance access. Exemplary implementations may: obtain, in an ongoing manner, state space information defining a present state of a virtual space instance; facilitate presentation of a view of the virtual space instance to users through graphical user interfaces; obtain one or more consideration provision channels associated with one or more of the users; monitor the state space information for circumstances in the virtual space instance that satisfy circumstantial triggers of consideration stream trigger definitions associated with the objects; responsive to detection of circumstances in the virtual space instance that satisfy the circumstantial triggers, automatically initiate one or more streams of consideration amounts from one or more consideration provision channels to one or more consideration reception channels.

Abstract: A shower system includes an inlet configured to receive water from a supply conduit and a plurality of spout outlets configured to discharge water from the shower system. A diverter is configured to receive water from the inlet and deliver water to the plurality of spout outlets, and the diverter is actuatable to change a water discharge mode of the plurality of spout outlets. A valve is configured to receive water from the inlet, and the valve is actuatable to a first position and a second position. A diverter actuator is configured to receive water from the valve in the second position. The diverter actuator is actuatable from an unactuated position to an actuated position upon receiving water from the valve, and the diverter actuator thereby actuates the diverter to change the water discharge mode of the plurality of spout outlets.

Abstract: The disclosure provides methods and systems for detecting alternative splicing variants in a patient sample. The methods involve comparison of splice junction data from RNA sequencing with principal splicing isoforms and identifying those sequences, identifying those sequences that do not match the principal splicing isoform. These sequences are categorized into alternative splicing events and documented. Optionally, previously identified target sequences can be utilized in the comparison where the method seeks sequences which do match. Other methods and systems of the present disclosure include those for building a splice profile of alternative splicing variants for a patient sample and those for developing a companion diagnostic test for a treatment method of a disease based on the presence or absence of alternative splicing variants in a patient sample.

Abstract: A grill cover is configured to be utilized with a grill having a metallic component, the grill cover includes a cover body, a magnetic fastener, and a secondary fastener. The cover body presents an outer edge disposed along a bottom side and a cover void therein configured to receive the grill therein. The magnetic fastener and the secondary fastener are each secured to the cover body. The magnetic fastener is configured to provide a magnetic force to keep the magnetic fastener selectively secured to the metallic component of the grill so as to keep the cover body in place around the grill therein. The secondary fastener is configured to reduce a cross-sectional area of the cover void so as to prevent the grill cover from being removed from the grill while the secondary fastener is emplaced.

Abstract: A sprayhead for use with a faucet including a soap compartment and a diverter valve configured to provide selective communication between the soap compartment and a water outlet.

Abstract: Computational algorithms integrate and analyze data to consider multiple interdependent, heterogeneous sources and forms of patient data, and using a classification model, provide new learning paradigms, including privileged learning and learning with uncertain clinical data, to determine patient status for conditions such as acute respiratory distress syndrome (ARDS) or non-ARDS.

Abstract: A shower system includes an inlet configured to receive water from a supply conduit and a plurality of spout outlets configured to discharge water from the shower system. A diverter is configured to receive water from the inlet and deliver water to the plurality of spout outlets, and the diverter is actuatable to change a water discharge mode of the plurality of spout outlets. A valve is configured to receive water from the inlet, and the valve is actuatable to a first position and a second position. A diverter actuator is configured to receive water from the valve in the second position. The diverter actuator is actuatable from an unactuated position to an actuated position upon receiving water from the valve, and the diverter actuator thereby actuates the diverter to change the water discharge mode of the plurality of spout outlets.

Abstract: Disclosed herein are systems, methods, and compositions useful for determining cellular pathway disruption comprising the use of RNA expression level information. This determined level of disruption can assist in the identification of genetic variants that alter pathway activity, to correlate these variants with disease state and disease progression, and to identify those therapeutics most likely to be effective and which should be avoided.

Abstract: Disclosed herein are systems, methods, and compositions useful for determining cellular pathway disruption comprising the use of RNA expression level information. This determined level of disruption can assist in the identification of genetic variants that alter pathway activity, to correlate these variants with disease state and disease progression, and to identify those therapeutics most likely to be effective and which should be avoided.

Abstract: A smart shower sensor configured to be fluidly coupled to a showerhead. The smart shower sensor is configured to provide notifications and/or transmit notifications to other smart devices based on, for example, water temperature and/or water usage.

Abstract: A grill cover is configured to be utilized with a grill having a metallic component, the grill cover includes a cover body, a magnetic fastener, and a secondary fastener. The cover body presents an outer edge disposed along a bottom side and a cover void therein configured to receive the grill therein. The magnetic fastener and the secondary fastener are each secured to the cover body. The magnetic fastener is configured to provide a magnetic force to keep the magnetic fastener selectively secured to the metallic component of the grill so as to keep the cover body in place around the grill therein. The secondary fastener is configured to reduce a cross-sectional area of the cover void so as to prevent the grill cover from being removed from the grill while the secondary fastener is emplaced.

Abstract: Systems and methods are provided for performing quality control analysis. The method obtains, in electronic form, a batch dataset comprising, for each respective sample in a batch of samples, a corresponding plurality of sequence reads derived from the respective sample by targeted or whole transcriptome RNA sequencing and corresponding metadata for the respective sample. The method determines for the batch dataset a cohort-matched reference batch, where the cohort-matched reference batch is balanced for tissue site, tumor purity, cancer type, sequencer identity, or date sequenced. The method performs one or more global batch quality control tests on the batch dataset using at least the cohort-matched reference batch. The method removes respective samples from the batch dataset that fail any one of the one or more global batch quality control tests or flagging for manual inspection respective samples that fail any one of the one or more global batch quality control tests.

Abstract: A shower system includes a showerhead, which includes a first diverter that is configured to deliver water to a plurality of showerhead outlets. The first diverter is actuatable to change a showerhead water discharge mode of the plurality of showerhead outlets. A diverter actuator is actuatable to actuate the first diverter and thereby change the showerhead water discharge mode of the plurality of showerhead outlets. The shower system further includes a handshower, which includes a second diverter that is configured to deliver water to a plurality of handshower outlets. The second diverter is actuatable to change a handshower water discharge mode of the plurality of handshower outlets. The shower system further includes a user interface that is configured to be actuated by a user to selectively and independently (1) deliver water from the handshower to the diverter actuator to actuate the diverter actuator, and (2) actuate the second diverter.

Abstract: Systems and methods are provided for performing quality control analysis. The method obtains, in electronic form, a batch dataset comprising, for each respective sample in a batch of samples, a corresponding plurality of sequence reads derived from the respective sample by targeted or whole transcriptome RNA sequencing and corresponding metadata for the respective sample. The method determines for the batch dataset a cohort-matched reference batch, where the cohort-matched reference batch is balanced for tissue site, tumor purity, cancer type, sequencer identity, or date sequenced. The method performs one or more global batch quality control tests on the batch dataset using at least the cohort-matched reference batch. The method removes respective samples from the batch dataset that fail any one of the one or more global batch quality control tests or flagging for manual inspection respective samples that fail any one of the one or more global batch quality control tests.

Abstract: Systems and methods are provided for performing quality control analysis. The method obtains, in electronic form, a batch dataset comprising, for each respective sample in a batch of samples, a corresponding plurality of sequence reads derived from the respective sample by targeted or whole transcriptome RNA sequencing and corresponding metadata for the respective sample. The method determines for the batch dataset a cohort-matched reference batch, where the cohort-matched reference batch is balanced for tissue site, tumor purity, cancer type, sequencer identity, or date sequenced. The method performs one or more global batch quality control tests on the batch dataset using at least the cohort-matched reference batch. The method removes respective samples from the batch dataset that fail any one of the one or more global batch quality control tests or flagging for manual inspection respective samples that fail any one of the one or more global batch quality control tests.

Abstract: An exposed secondary showerhead system configured to be supported by a conventional shower enclosure. The illustrative showerhead system includes an overhead conduit fluidly coupled to a conventional shower inlet pipe and to at least one showerhead.