Patents by Inventor Joshua Dwork

Joshua Dwork has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11801137
    Abstract: Methods of deploying and securing a heart valve prosthesis are disclosed. A heart valve prosthesis having a plurality of anchor guides is loaded within a catheter-based delivery device, wherein each of the anchor guides is releasably engaged by a respective elongate member and wherein tensioning of the elongate members aids in collapsing the prosthesis during loading. The delivery device is advanced via a transcatheter procedure to position the heart valve prosthesis at an implantation site. The heart valve prosthesis undergoes controlled deployment by controlling the release of tension on the elongate members. After deployment of the heart valve prosthesis, an anchor tool is advanced along at least one elongate guide member to the anchor guide associated therewith and positioned at a securement site. When the securement site is reached, an anchor clip is released from the anchor tool to secure the prosthesis to the heart.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: October 31, 2023
    Assignee: Medtronic Vascular, Inc.
    Inventors: Niall Duffy, Joshua Dwork
  • Patent number: 11786370
    Abstract: Systems for delivering prosthetic heart valve devices can include, for example, an elongated catheter body, a deliver capsule carried by the catheter body, and an expandable atraumatic member. The delivery capsule includes a platform and a housing having an outer wall and a proximal rim, and the platform is configured to be releasably coupled to a prosthetic heart valve device. The housing is configured to slide along the platform from a containment configuration to a deployment configuration. The expandable atraumatic member has an atraumatic surface and a peripheral portion. The atraumatic member has a compacted configuration and an expanded configuration in which the peripheral portion extends laterally outward over the proximal rim of the housing to protect tissue of the heart and the vasculature from potentially being damaged by the proximal rim of the housing as the delivery system is withdrawn in a proximal direction through the patient.
    Type: Grant
    Filed: October 5, 2020
    Date of Patent: October 17, 2023
    Assignee: Twelve, Inc.
    Inventors: Kevin Mauch, Joshua Dwork, Finn Rinne, Siyan Som, Estella Wong
  • Publication number: 20230310157
    Abstract: A transcatheter valve prosthesis including a tubular stent includes an interior skirt or skirt portion is coupled to and covers an inner circumferential surface of the stent, and an exterior skirt or skirt portion is coupled to and covers an outer circumferential surface of the stent. A prosthetic valve component is disposed within and secured to the interior skirt or skirt portion. The interior and exterior skirts or skirt portions may overlap to form a double layer of skirt material on the stent, or may be portions of a skirt that do not overlap such that only a single layer of skirt material covers the stent. When the stent is in at least the compressed configuration, at least one endmost crown may be positioned radially inwards with respect to the remaining endmost crowns formed at the inflow end of the stent in order to accommodate the exterior skirt.
    Type: Application
    Filed: June 7, 2023
    Publication date: October 5, 2023
    Inventors: Joshua Dwork, Scott Mosher
  • Patent number: 11717407
    Abstract: A transcatheter valve prosthesis including a tubular stent includes an interior skirt or skirt portion is coupled to and covers an inner circumferential surface of the stent, and an exterior skirt or skirt portion is coupled to and covers an outer circumferential surface of the stent. A prosthetic valve component is disposed within and secured to the interior skirt or skirt portion. The interior and exterior skirts or skirt portions may overlap to form a double layer of skirt material on the stent, or may be portions of a skirt that do not overlap such that only a single layer of skirt material covers the stent. When the stent is in at least the compressed configuration, at least one endmost crown may be positioned radially inwards with respect to the remaining endmost crowns formed at the inflow end of the stent in order to accommodate the exterior skirt.
    Type: Grant
    Filed: January 23, 2019
    Date of Patent: August 8, 2023
    Assignee: MEDTRONIC VASCULAR, INC.
    Inventors: Joshua Dwork, Scott Mosher
  • Publication number: 20230218396
    Abstract: A delivery system for delivering a heart valve prosthesis includes a heart valve prosthesis and a delivery catheter. The heart valve prosthesis includes an anchoring member and an inner valve support, and further includes a radially collapsed configuration and a radially expanded configuration. The delivery catheter includes a handle, an outer shaft, an intermediate shaft, an inner shaft, and a distal tip component. The delivery catheter further includes a delivery configuration. In the delivery configuration, the outer shaft of the delivery catheter is configured to retain a first portion of the anchoring member, the intermediate shaft is configured to retain a first portion of the inner valve support, and the distal tip component is configured to retain a second end of the anchoring member and a second end of the inner valve support each in a radially compressed state.
    Type: Application
    Filed: March 22, 2023
    Publication date: July 13, 2023
    Inventors: James Keogh, Joshua Dwork
  • Publication number: 20230144613
    Abstract: Delivery systems with telescoping capsules for delivering prosthetic heart valve devices and associated methods are disclosed herein. A delivery system configured in accordance with embodiments of the present technology can include, for example, a delivery capsule having a first housing, a second housing slidably disposed within a portion of the first housing, and a prosthetic device constrained within the first and second housings. During deployment, the first housing is moved in a first direction over the second housing, thereby releasing a first portion of the prosthetic device. Subsequently, fluid the second housing is moved in the first direction to release a second portion of the prosthetic device.
    Type: Application
    Filed: January 6, 2023
    Publication date: May 11, 2023
    Inventors: Kevin Mauch, Joshua Dwork
  • Patent number: 11612482
    Abstract: A delivery system for delivering a heart valve prosthesis includes a heart valve prosthesis and a delivery catheter. The heart valve prosthesis includes an anchoring member and an inner valve support, and further includes a radially collapsed configuration and a radially expanded configuration. The delivery catheter includes a handle, an outer shaft, an intermediate shaft, an inner shaft, and a distal tip component. The delivery catheter further includes a delivery configuration. In the delivery configuration, the outer shaft of the delivery catheter is configured to retain a first portion of the anchoring member, the intermediate shaft is configured to retain a first portion of the inner valve support, and the distal tip component is configured to retain a second end of the anchoring member and a second end of the inner valve support each in a radially compressed state.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: March 28, 2023
    Assignee: MEDTRONIC, INC.
    Inventors: James Keogh, Joshua Dwork
  • Patent number: 11559398
    Abstract: Delivery systems with telescoping capsules for delivering prosthetic heart valve devices and associated methods are disclosed herein. A delivery system configured in accordance with embodiments of the present technology can include, for example, a delivery capsule having a first housing, a second housing slidably disposed within a portion of the first housing, and a prosthetic device constrained within the first and second housings. The delivery capsule can further include first and second chamber defined in part by the first and second housings. During deployment, fluid is delivered to the first chamber to move the first housing distally over the second housing, thereby releasing a portion of the prosthetic device. Subsequently, fluid is delivered to the second chamber such that the first and second housings move together in the distal direction to release a second portion of the prosthetic device.
    Type: Grant
    Filed: May 8, 2020
    Date of Patent: January 24, 2023
    Assignee: Twelve, Inc.
    Inventors: Kevin Mauch, Joshua Dwork
  • Publication number: 20230014019
    Abstract: An apparatus for hydraulic deployment and recapture of an implant includes a hydraulic implant uncovering mechanism and a hydraulic implant re-covering mechanism. The implant uncovering mechanism and the implant re-covering mechanism are independently actuateable with a fluid, and the implant uncovering mechanism is coupled to the implant re-covering mechanism by a flexible elongate tether.
    Type: Application
    Filed: June 23, 2022
    Publication date: January 19, 2023
    Inventors: Erik C. Griswold, Kenny D. Bruner, Joshua Dwork, Austin Haynes
  • Publication number: 20230016149
    Abstract: A delivery system for prosthetic heart valves are provided. The delivery system includes a flexible shaft, a distal sheath capsule configured to contain the prosthetic heart valve, an inner steerable catheter including an inner distal flex component, and an outer steerable catheter including an outer distal flex component. The inner distal flex component includes a first cut pattern and a second cut pattern distal to the first cut pattern. The outer distal flex component includes a third cut pattern. The inner steerable catheter is rotatable at least 90 degrees relative to the outer steerable catheter when the third cut pattern of the outer distal flex component is disposed over at least a portion of the first cut pattern of the inner distal flex component and each of the inner steerable catheter and the outer steerable catheter is in the flexed configuration.
    Type: Application
    Filed: May 31, 2022
    Publication date: January 19, 2023
    Inventors: Erik GRISWOLD, Joshua DWORK, Jamie DUNAWAY, Finn RINNE, Nathan WIEMEYER, Kevin MAUCH
  • Patent number: 11523904
    Abstract: A tool for use in loading a transcatheter valve prosthesis within a delivery catheter includes a body portion, a pivotable element and a biasing element. The body portion includes a central passageway extending form a proximal end to a distal end of the body portion. The central passageway is configured to receive a distal portion of a delivery catheter therethrough. The pivotable element is attached to the body portion and is configured to secure a tether during loading of a transcatheter valve prosthesis within the delivery catheter. The biasing element compresses the pivotable element against the body portion such that the pivotable element holds a second end against the delivery catheter and secures the tether thereto. The pivotable element may be two or more pivotable elements.
    Type: Grant
    Filed: June 1, 2020
    Date of Patent: December 13, 2022
    Assignee: Medtronic Vascular, Inc.
    Inventor: Joshua Dwork
  • Publication number: 20220183833
    Abstract: A prosthesis can include a collapsible, reexpandable frame comprising first, second, and third sets of struts that define first and second rows of expandable cells. In some embodiments, the struts of the first, second, and third set of struts can be tapered. In some embodiments, the frame can include an intermediate section and an inflow section that is proximal to the intermediate section. The inflow section can include a concave saddle portion that is adjacent the intermediate section, and an outwardly flared portion.
    Type: Application
    Filed: March 7, 2022
    Publication date: June 16, 2022
    Inventors: Padraig SAVAGE, Joseph CALLOL, Alaena DESTEFANO, Joshua DWORK, Devin GOSAL, Karan PUNGA, Finn RINNE, Billy TAM
  • Patent number: 11298226
    Abstract: A prosthesis can include a collapsible, reexpandable frame comprising first, second, and third sets of struts that define first and second rows of expandable cells. In some embodiments, the struts of the first, second, and third set of struts can be tapered. In some embodiments, the frame can include an intermediate section and an inflow section that is proximal to the intermediate section. The inflow section can include a concave saddle portion that is adjacent the intermediate section, and an outwardly flared portion.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: April 12, 2022
    Assignee: MEDTRONIC CV LUXEMBOURG S.A.R.L.
    Inventors: Padraig Savage, Joseph Callol, Alaena Destefano, Joshua Dwork, Devin Gosal, Karan Punga, Finn Rinne, Billy Tam
  • Patent number: 11278402
    Abstract: A prosthesis having a radially expanded configuration and a radially compressed configuration includes a frame with a plurality of infolding longitudinal segments. Each of the infolding longitudinal segments of the frame extend an entire length of the frame and is configured to deform radially inward when the prosthesis is in the radially compressed configuration such that a series of longitudinally aligned apices of each infolding longitudinal segment is disposed radially inward of the remainder of the prosthesis. In an embodiment, the frame also includes a plurality of outfolding longitudinal segments. Each of the outfolding longitudinal segments of the frame extend an entire length of the frame and is configured to deform radially outward when the prosthesis is in the radially compressed configuration such that a series of longitudinally aligned apices of each outfolding longitudinal segment is disposed radially outward of the remainder of the prosthesis.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: March 22, 2022
    Assignee: MEDTRONIC, INC.
    Inventors: John Morriss, Joshua Dwork, Nathaniel Piland, Finn Rinne, David Grossman
  • Patent number: 11278397
    Abstract: Prosthetic heart valve devices and associated methods for percutaneous or transcatheter heart valve replacement are disclosed herein. A heart valve prosthesis configured in accordance herewith includes a frame having a valve support and a plurality of support arms extending therefrom. The plurality of support arms may include a main support arm configured to extend from the valve support for capturing at least a portion of a valve leaflet of a native heart valve therebetween when the valve prosthesis is in an expanded configuration and deployed within the native heart valve. In addition, the plurality of support arms may include multiple supplemental support arms disposed about the circumference of the valve support that when deployed in the expanded configuration are configured to at least partially engage subannular tissue at the native heart valve.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: March 22, 2022
    Assignee: MEDTRONIC, INC.
    Inventors: Jason Quill, Padraig Savage, Joshua Dwork, Kshitija Garde, Sarah Ahlberg, Igor Kovalsky
  • Publication number: 20220054266
    Abstract: Heart valve prosthesis are disclosed that include a frame or support structure having an inflow portion, a valve-retaining tubular or central portion and a pair of support arms. The inflow portion radially extends from a first end of the valve-retaining tubular portion and the pair of support arms are circumferentially spaced apart and radially extend from an opposing second end of the valve-retaining tubular portion.
    Type: Application
    Filed: September 2, 2021
    Publication date: February 24, 2022
    Inventors: Igor KOVALSKY, Cathleen BERGIN, Marian CREAVEN, Joshua DWORK, Kshitija GARDE, Daniel GLOZMAN, Ilia HARITON, Pham LO, Jason QUILL, Jeffrey SANDSTROM, Padraig SAVAGE, Michael SCHENDEL, Elizabeth SCHOTZKO, Yossi TUVAL, Nadav YELLIN
  • Publication number: 20210085450
    Abstract: Systems for delivering prosthetic heart valve devices can include, for example, an elongated catheter body, a deliver capsule carried by the catheter body, and an expandable atraumatic member. The delivery capsule includes a platform and a housing having an outer wall and a proximal rim, and the platform is configured to be releasably coupled to a prosthetic heart valve device. The housing is configured to slide along the platform from a containment configuration to a deployment configuration. The expandable atraumatic member has an atraumatic surface and a peripheral portion. The atraumatic member has a compacted configuration and an expanded configuration in which the peripheral portion extends laterally outward over the proximal rim of the housing to protect tissue of the heart and the vasculature from potentially being damaged by the proximal rim of the housing as the delivery system is withdrawn in a proximal direction through the patient.
    Type: Application
    Filed: October 5, 2020
    Publication date: March 25, 2021
    Inventors: Kevin Mauch, Joshua Dwork, Finn Rinne, Siyan Som, Estella Wong
  • Publication number: 20210077258
    Abstract: A heart valve therapy system including a delivery device and a stented valve. The delivery device includes an outer sheath, an inner shaft, an optional hub assembly, and a plurality of tethers. In a delivery state, a stent frame of the prosthesis is crimped over the inner shaft and maintained in a compressed condition by the outer sheath. The tethers are connected to the stent frame. In a partial deployment state, the outer sheath is at least partially withdrawn, allowing the stent frame to self-expand. Tension in the tethers prevents the stent frame from rapidly expanding and optionally allowing recapture. Upon completion of the stent frame expansion, the tethers are withdrawn.
    Type: Application
    Filed: December 1, 2020
    Publication date: March 18, 2021
    Applicant: Medtronic Vascular Galway
    Inventors: Marian Creaven, Marc Anderson, Kate Corish, Declan Costello, Niall Duffy, Joshua Dwork, John Gallagher, Patrick Griffin, Gavin Kenny, Deirdre McGowan Smyth, John Milroy, Jason Quill, Herinaina Rabarimanantsoa Jamous, Paul Rothstein, Jeffrey Sandstrom, Edmond Sheahan, Frank White
  • Publication number: 20210068950
    Abstract: Prosthetic heart valve devices and associated methods for percutaneous or transcatheter heart valve replacement are disclosed herein. A heart valve prosthesis configured in accordance herewith includes a frame having a valve support and a plurality of support arms extending therefrom. The plurality of support arms may include a main support arm configured to extend from the valve support for capturing at least a portion of a valve leaflet of a native heart valve therebetween when the valve prosthesis is in an expanded configuration and deployed within the native heart valve. In addition, the plurality of support arms may include multiple supplemental support arms disposed about the circumference of the valve support that when deployed in the expanded configuration are configured to at least partially engage subannular tissue at the native heart valve.
    Type: Application
    Filed: November 11, 2020
    Publication date: March 11, 2021
    Inventors: Jason Quill, Padraig Savage, Joshua Dwork, Kshitija Garde, Sarah Ahlberg, Igor Kovalsky
  • Patent number: 10869761
    Abstract: A heart valve therapy system including a delivery device and a stented valve. The delivery device includes an outer sheath, an inner shaft, an optional hub assembly, and a plurality of tethers. In a delivery state, a stent frame of the prosthesis is crimped over the inner shaft and maintained in a compressed condition by the outer sheath. The tethers are connected to the stent frame. In a partial deployment state, the outer sheath is at least partially withdrawn, allowing the stent frame to self-expand. Tension in the tethers prevents the stent frame from rapidly expanding and optionally allowing recapture. Upon completion of the stent frame expansion, the tethers are withdrawn.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: December 22, 2020
    Assignee: Medtronic Vascular Galway
    Inventors: Marian Creaven, Marc Anderson, Kate Corish, Declan Costello, Niall Duffy, Joshua Dwork, John Gallagher, Patrick Griffin, Gavin Kenny, Deirdre McGowan Smyth, John Milroy, Jason Quill, Herinaina Rabarimanantsoa Jamous, Paul Rothstein, Jeffrey Sandstrom, Edmond Sheahan, Frank White