Abstract: Systems and methods for rules-based decisioning of events are disclosed. In one embodiment, a method may include: creating an in-memory cache by parsing stored checkpoints, signals, and rules definitions; receiving a checkpoint request; prioritizing the checkpoint request; preparing a basic context, comprising a limited set of objects, for the checkpoint request; using the in-memory cached definitions, generating at least one of a raw signal, an engineered signal, and a secondary signal for the checkpoint request based on the basic context; using the in-memory cached definitions, executing rules on at least one of the basic context, the raw signal, the engineered signal, and the secondary signal to generate a list of potential decisions; reducing the list of potential decisions to a list of final decisions; publishing the final decisions and supporting data rules and signals execution details; and executing the final decisions.

Abstract: Systems and methods for rules-based decisioning of events are disclosed. In one embodiment, a method may include: creating an in-memory cache by parsing stored checkpoints, signals, and rules definitions; receiving a checkpoint request; prioritizing the checkpoint request; preparing a basic context, comprising a limited set of objects, for the checkpoint request; using the in-memory cached definitions, generating at least one of a raw signal, an engineered signal, and a secondary signal for the checkpoint request based on the basic context; using the in-memory cached definitions, executing rules on at least one of the basic context, the raw signal, the engineered signal, and the secondary signal to generate a list of potential decisions; reducing the list of potential decisions to a list of final decisions; publishing the final decisions and supporting data rules and signals execution details; and executing the final decisions.

Abstract: The invention is directed to a microarray assay procedure that can be used for profiling the antibodies present in serum, plasma or blood. The assay may be used to identify antibodies and antigens that are characteristic of particular diseases or conditions. In addition, the invention includes specific antigens that are associated with prostate cancer, progressive benign prostate hyperplasia (BPH) and ovarian cancer.

Abstract: The invention is directed to tumor associated markers (TAMs) that can be used diagnostically, especially in the diagnosis of prostate cancer and other markers (BPHMs) that can be used in the diagnosis of benign prostate hyperplasia. It also includes glass or plastic plates or slides on which the TAMs or BPHMs have been immobilized.