Abstract: The invention relates to devices and methods for affecting an internal body tube, such as the esophagus, particularly to affecting the internal body tube by inserting a device into the internal body tube and more particularly to affecting the internal body tube by at least partially sealing off a section and moving the walls of the internal body tube, and/or applying cooling to the internal body tube. This invention further relates to methods of using such devices to move portions of an internal body tube away from an area undergoing a treatment or therapy, such as to minimize damage to the internal body tube, and/or providing cooling/temperature monitoring.