Patents by Inventor Joshua J. Levy

Joshua J. Levy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12293836
    Abstract: This invention provides a histologic system and method for rapidly and accurately assessing tumor margins for the presence or absence of tumor using machine learning algorithms. This affords a rapid and accurate histologic tumor readout and increase process efficiency and decreases the chance for human error. Advantageously and uniquely, the system and method allows for analyzing the tissue section as complete or incomplete as the first criteria to determine whether a tissue section is clear of tumor. A machine learning process receives whole slide images (WSI) of tissue and determines (a) if each image of the WSI contains complete/incomplete tissue samples and (b) if each image of the WSI contains tumorous tissue or an absence thereof. A reconstruction process generates a model of the tissue that maps types of tissue therein, and a display process provides results of the model or report for use and manipulation by a user.
    Type: Grant
    Filed: November 27, 2023
    Date of Patent: May 6, 2025
    Assignee: Dartmouth-Hitchcock Clinic
    Inventors: Matthew LeBoeuf, Louis J. Vaickus, Joshua J. Levy
  • Publication number: 20240420845
    Abstract: This invention provides a system for automation of a pathology process, which includes a processor having trained artificial intelligence (AI) modules operating in association therewith, adapted to receive image data from camera images of whole tissue acquired by a camera assembly and whole slide images (WSIs) of inked and segmented tissue samples. A mask produces image results for tissue with holes and free of holes, and a filter provides filtered image results to the AI modules, detecting tumors and macroarchitecture features. A quality assessment process produces quality score outputs for tumors and macroarchitecture features. A report generator provides reports with one or more parameters to a user via an interface. More particularly, the report generator automatically creates a pathology report, having a written description and pictorial diagram relative to the gross images of the tissue integrating the outputs of the AI modules used to analyze the whole slide digital images.
    Type: Application
    Filed: June 17, 2024
    Publication date: December 19, 2024
    Inventors: Matthew LeBoeuf, Joshua J. Levy, Louis J. Vaickus
  • Patent number: 12014830
    Abstract: This invention provides a system for automation of a pathology process, which includes a processor having trained artificial intelligence (AI) modules operating in association therewith, adapted to receive image data from camera images of whole tissue acquired by a camera assembly and whole slide images (WSIs) of inked and segmented tissue samples. A mask produces image results for tissue with holes and free of holes, and a filter provides filtered image results to the AI modules, detecting tumors and macroarchitecture features. A quality assessment process produces quality score outputs for tumors and macroarchitecture features. A report generator provides reports with one or more parameters to a user via an interface. More particularly, the report generator automatically creates a pathology report, having a written description and pictorial diagram relative to the gross images of the tissue integrating the outputs of the AI modules used to analyze the whole slide digital images.
    Type: Grant
    Filed: April 18, 2022
    Date of Patent: June 18, 2024
    Assignee: Mary Hitchcock Memorial Hospital, for itself and on behalf of Dartmouth-Hitchcock Clinic
    Inventors: Matthew LeBoeuf, Joshua J. Levy, Louis J. Vaickus
  • Publication number: 20240170152
    Abstract: This invention provides a histologic system and method for rapidly and accurately assessing tumor margins for the presence or absence of tumor using machine learning algorithms. This affords a rapid and accurate histologic tumor readout and increase process efficiency and decreases the chance for human error. Advantageously and uniquely, the system and method allows for analyzing the tissue section as complete or incomplete as the first criteria to determine whether a tissue section is clear of tumor. A machine learning process receives whole slide images (WSI) of tissue and determines (a) if each image of the WSI contains complete/incomplete tissue samples and (b) if each image of the WSI contains tumorous tissue or an absence thereof. A reconstruction process generates a model of the tissue that maps types of tissue therein, and a display process provides results of the model or report for use and manipulation by a user.
    Type: Application
    Filed: November 27, 2023
    Publication date: May 23, 2024
    Inventors: Matthew LeBoeuf, Louis J. Vaickus, Joshua J. Levy
  • Patent number: 11830621
    Abstract: This invention provides a histologic system and method for rapidly and accurately assessing tumor margins for the presence or absence of tumor using machine learning algorithms. This affords a rapid and accurate histologic tumor readout and increase process efficiency and decreases the chance for human error. Advantageously and uniquely, the system and method allows for analyzing the tissue section as complete or incomplete as the first criteria to determine whether a tissue section is clear of tumor. A machine learning process receives whole slide images (WSI) of tissue and determines (a) if each image of the WSI contains complete/incomplete tissue samples and (b) if each image of the WSI contains tumorous tissue or an absence thereof. A reconstruction process generates a model of the tissue that maps types of tissue therein, and a display process provides results of the model or report for use and manipulation by a user.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: November 28, 2023
    Assignee: Dartmouth-Hitchcock Clinic
    Inventors: Matthew LeBoeuf, Louis J. Vaickus, Joshua J. Levy
  • Publication number: 20220375604
    Abstract: This invention provides a system for automation of a pathology process, which includes a processor having trained artificial intelligence (AI) modules operating in association therewith, adapted to receive image data from camera images of whole tissue acquired by a camera assembly and whole slide images (WSIs) of inked and segmented tissue samples. A mask produces image results for tissue with holes and free of holes, and a filter provides filtered image results to the AI modules, detecting tumors and macroarchitecture features. A quality assessment process produces quality score outputs for tumors and macroarchitecture features. A report generator provides reports with one or more parameters to a user via an interface. More particularly, the report generator automatically creates a pathology report, having a written description and pictorial diagram relative to the gross images of the tissue integrating the outputs of the AI modules used to analyze the whole slide digital images.
    Type: Application
    Filed: April 18, 2022
    Publication date: November 24, 2022
    Inventors: Matthew LeBoeuf, Joshua J. Levy, Louis J. Vaickus