Patents by Inventor Joshua L. Dunaief

Joshua L. Dunaief has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLP-1R AGONIST REDUCES RETINAL INFLAMMATION AND NEURON DEATH SECONDARY TO OCULAR HYPERTENSION
    Publication number: 20220193201
    Abstract: Methods for reducing retinal inflammation and neuron death secondary to ocular hypertension, methods for reducing retinal inflammation and neuron death, reducing production of IL-1?, TNF-?, and C1q by CD11b+ CD11c+ and CD11b+ CD11c? cells during elevated intraocular pressure (IOP) and methods for decreasing transformation of astrocytes to an A1 neurotoxic phenotype (A1 astrocytes) and activation of the A1 astrocytes in a retina of a subject and decreasing production of complement component 3 (C3) by A1 astrocytes during elevated intraocular pressure in a subject in need thereof, comprising administering a glucagon-like peptide-1 receptor agonist.
    Type: Application
    Filed: October 18, 2021
    Publication date: June 23, 2022
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Qi N. Cui, Joshua L. Dunaief, Jacob Sterling
  • Use of salicylaldehyde isonicotinoyl hydrazone (SIH) for protection against retinal disease
    Patent number: 8501789
    Abstract: This invention relates to methods for treating age-related macular degeneration, blindness or glaucoma using an iron-chelator SIH.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: August 6, 2013
    Assignee: The Trustees of the University of Pennsylvania
    Inventor: Joshua L. Dunaief
  • Use of salicylaldehyde isonicotinoyl hydrazone (SIH) for protection against retinal disease
    Publication number: 20080279913
    Abstract: This invention relates to methods for treating age-related macular degeneration, blindness or glaucoma using an iron-chelator SIH.
    Type: Application
    Filed: January 18, 2008
    Publication date: November 13, 2008
    Inventor: Joshua L. Dunaief