Abstract: Devices and methods for blood flow enhancement and hemodynamic power monitoring are provided. A blood flow enhancement device includes a pump system configured to be coupled to a central vasculature of a subject during cardiopulmonary resuscitation (CPR). The pump system includes a pumping mechanism configured to increase forward blood flow generated during the CPR while substantially limiting backward blood flow generated during the CPR. The pumping mechanism being operated concurrently with the CPR. The hemodynamic power monitor is configured to control a chest compression device and an active valve.

Abstract: A system for assisting with a chest compression treatment being administered to a patient. In one aspect, the system for assisting with chest compression treatment includes at least one sensor configured to measure blood flow data, one or more processors, in communication with the at least one sensor, and an output device configured to provide the output indication to the rescuer. The one or more processors are configured to perform operations including receiving the blood flow data from the at least one sensor, based on the blood flow data, generating arterial blood flow data and venous blood flow data, providing an estimation of chest compression effectiveness based on the arterial blood flow data and the venous blood flow data, the estimation being based on at least one peak comparison of arterial blood flow and venous blood flow, and generating an output indication of the estimation of chest compression effectiveness.

Abstract: A frozen particulate slurry comprises a first component and a second component which are capable of forming a eutectic mixture. The slurry is formed by cooling a composition comprising the first and second components to a temperature below the freezing point of the first component to form particles of the first component, and then cooling to freeze a eutectic mixture of the first component and the second component. A method of thawing the frozen particulate slurry comprises heating the slurry, and an apparatus for thawing the frozen particulate slurry comprises a container for holding the particulate slurry, a heat source, and an agitator. A method of inducing therapeutic hypothermia in a patient comprises heating the frozen particulate slurry and administering the particulate slurry to the patient in an amount sufficient to locally or systemically induce therapeutic hypothermia.

Abstract: Devices and methods for blood flow enhancement and hemodynamic power monitoring are provided. A blood flow enhancement device includes a pump system configured to be coupled to a central vasculature of a subject during cardiopulmonary resuscitation (CPR). The pump system includes a pumping mechanism configured to increase forward blood flow generated during the CPR while substantially limiting backward blood flow generated during the CPR. The pumping mechanism being operated concurrently with the CPR. The hemodynamic power monitor is configured to control a chest compression device and an active valve.

Abstract: The present invention is related to a blood vessel locator and a method for locating blood vessels. In one or more embodiments, the locator comprises at least one filiform element, a sensor device and a display. The filiform elements are connected to the sensor device, which is arranged to detect a parameter indicative of the presence of a blood vessel and connected to a display, and the display is arranged to give an indication of vessel location.

Abstract: The present invention is a vessel detector comprising a sensor, a display and an access device for positioning the sensor in a detection area. According to the invention the sensor device is an impedance sensor. The invention comprises also a method for locating vessels comprising impedance measuring.