Abstract: An implantable medical device includes an expandable frame that is expandable between a collapsed configuration for delivery and an expanded configuration for deployment, the expandable frame including a periphery defined by the expandable frame. A covering spans at least part of the expandable frame. An expandable element is secured relative to the periphery, the expandable element is adapted to seal against an irregular body opening such as an irregular-shaped ostium of a patient's LAA (left atrial appendage).

Abstract: Provided is an apparatus that includes a first reservoir system including a first fluid reservoir configured to be in fluid communication with a nozzle supply system during operation of the nozzle supply system, a second reservoir system including a second fluid reservoir configured to be, at least part of the time during operation of the nozzle supply system, in fluid communication with the first reservoir system, a priming system configured to produce a fluid target material from a solid matter, and a fluid control system fluidly connected to the priming system, the first reservoir system, the second reservoir system, and the nozzle supply system. The fluid control system is configured to, during operation of the nozzle supply system: isolate at least one fluid reservoir and the nozzle supply system from the priming system, and maintain a fluid flow path between at least one fluid reservoir and the nozzle supply system.

Abstract: An implantable medical device such as but not limited to a left atrial appendage closure (LAAC) device includes an expandable frame that is movable between a collapsed configuration for delivery and an expanded configuration for deployment. The expandable frame may include a plurality of articulating members that are biased into the expanded configuration. The expandable frame may include a biasing member. The LAAC device includes a membrane or covering that spans across an end of the expandable frame.

Abstract: A medical device system may include an occlusive implant including a central hub and a plurality of elongate members configured to shift between extended and radially expanded configurations. The central hub includes a plurality of conduits extending from a proximal end to a radially outward facing surface. The plurality of elongate members is configured to extend through the conduits in the radially expanded configuration. An implant remodeling tool may include an elongate sheath having at least one lumen, a plunger guide, and a plurality of plunger shafts extending from the at least one lumen through the plunger guide. The plunger guide is configured to direct the plunger shafts radially outward as the plunger shafts are advanced distally. The plunger shafts are configured to engage a medical implant and urge at least a portion of the implant radially outward.

Abstract: An implant for occluding a left atrial appendage may include an expandable framework configured to shift between a collapsed configuration and an expanded configuration, wherein the expandable framework includes an attachment point configured to secure the expandable framework to a delivery device, and an occlusive element disposed on a proximal portion of the expandable framework, wherein the occlusive element covers the attachment point.

Abstract: Systems and methods for tracking the position of one or more objects, such as components of a head-mounted display (HMD) system. One or more objects may carry a plurality of angle sensitive optical detectors. Each of the optical detectors may include an optical subsystem that is configured to vary at least one of phase or intensity of light imparted on the optical detector. The optical subsystem may include one or more of diffractive optical elements, lens arrays, intensity masks, phase masks, or the like. The optical detectors may include a photodetector that includes a plurality of optically active areas, such as a quadrant cell photodetector, an image sensor with an array of photodiodes, etc. Control circuitry may cause light sources to emit light, and may receive sensor data from the plurality of optical detectors. Control circuitry may process the sensor data to track a position of one or more objects.

Abstract: Described herein are active noise reduction (ANR) techniques for reducing noise produced by a fan(s) of a head-mounted display (HMD). An example process may include receiving data indicative of a noise that is being produced by the fan(s), determining, based at least in part on the data and using a model(s), one or more audio parameter values, and outputting, via one or more off-ear speakers of the HMD, a sound(s) having one or more audio characteristics based at least in part on the one or more audio parameter values to reduce the noise produced by the fan(s) at a location(s) of an ear(s) of the user of the HMD.

Abstract: Systems and methods for tracking the position of one or more head-mounted display (HMD) system components of an HMD system. The HMD components may carry a plurality of angle sensitive detectors or other types of detectors. The HMD system may be operative to detect corrupted position tracking samples, allowing such samples to be ignored, thereby improving the position tracking process. Control circuitry causes light sources to emit light according a specified pattern, and receives sensor data from the plurality of detectors. Control circuitry may process the sensor data, for example using machine learning or other techniques, to track a position of one or more HMD components.

Abstract: A medical implant for occluding a left atrial appendage may include an expandable framework configured to shift between a collapsed configuration and an expanded configuration. The expandable framework may include a plurality of interconnected struts and a plurality of anchor members extending radially outward from the plurality of interconnected struts in the expanded configuration. Each anchor member of the plurality of anchor members may include a base portion fixedly attached to the plurality of interconnected struts and an anchor tip portion. The anchor tip portion may include a central penetrating element and at least one tissue support element extending outward from the central penetrating element. The at least one tissue support element may be configured to be non-penetrating.

Abstract: An implantable medical device such as but not limited to a left atrial appendage closure (LAAC) device includes an expandable frame that is movable between a collapsed configuration for delivery and an expanded configuration for deployment. The expandable frame may include a plurality of frame members that are biased into the expanded configuration. The expandable frame may include a biasing member. The LAAC device includes a membrane or covering that spans across an end of the expandable frame.

Abstract: A medical implant for occluding a left atrial appendage may include an expandable framework configured to shift radially between a first configuration and a second configuration, and an occlusive element secured to the expandable framework. The framework includes a plurality of strut groups, each strut group comprising first and second joints, and first, second, and third struts. The first and second struts move laterally from a first position in the first configuration to a second position in the second configuration. The third strut is configured to shift radially from a first position in the first configuration to a second position in the second configuration. The first and second struts and a majority of the third struts of each strut group may be oriented parallel to each other in the first configuration and nonparallel to each other in the second configuration.

Abstract: A delivery system for deploying a medical implant includes a delivery catheter with a lumen, an elongate shaft axially slidably within the lumen, a housing attached to the elongate shaft, and an actuation element disposed within the housing and configured to axially advance and retract the elongate shaft. The actuation element is in direct contact with the elongate shaft and rotation of the actuation element causes axial movement of the elongate shaft.

Abstract: An example occlusive implant is disclosed. The example occlusive implant includes an expandable framework configured to shift between a collapsed configuration and an expanded configuration, wherein the expandable framework includes a plurality of strut members circumferentially spaced around a longitudinal axis of the expandable framework, wherein one or more of the plurality of strut members includes a first twisted portion and a face portion. The occlusive implant also includes a plurality of fixation members disposed along the face portion of one or more of the plurality of strut members.

Abstract: An example medical device for occluding the left atrial appendage is disclosed. The example medical device for occluding the left atrial appendage includes an expandable member having a first end region, a second end region and an inflation cavity. The example medical device includes at least one fixation member having a first end and a second end coupled to the expandable member. The at least one fixation member is configured to move from a delivery configuration to a deployed configuration in response to an expansion of the expandable member. Additionally, the example medical device includes a valve member extending at least partially into the inflation cavity and the expandable member is configured to expand and seal the opening of the left atrial appendage.

Abstract: An implantable medical device such as but not limited to a left atrial appendage closure (LAAC) device includes an expandable frame that is movable between a collapsed configuration for delivery and an expanded configuration for deployment, the expandable frame including a proximal portion, a distal portion and an intervening intermediate portion. The expandable frame includes a plurality of anchors extending about a periphery of the expandable frame. A primary covering extends over the proximal portion of the expandable frame and may interact with the plurality of anchors. A secondary covering extends over part of the expandable frame.

Abstract: A medical implant for occluding a left atrial appendage may include an expandable framework configured to shift between a collapsed configuration and an expanded configuration, and an occlusive element secured to the expandable framework. The expandable framework includes a proximal hub and a plurality of interconnected struts extending from the proximal hub, the plurality of interconnected struts defining a main body in the expanded configuration. The expandable framework includes a plurality of elongate anchoring appendages extending from the main body, the plurality of elongate anchoring appendages each including a plurality of anchoring barbs extending therefrom.

Abstract: A medical implant for occluding a left atrial appendage includes an expandable framework configured to shift between a first configuration and a second configuration, and an occlusive element secured to the expandable framework. The expandable framework includes a plurality of interconnected struts extending from a proximal hub. The plurality of interconnected struts includes a first plurality of struts and a second plurality of struts. In the second configuration, the first plurality of struts each extend radially along a first strut path from the proximal hub to one of a first plurality of strut intersections, and the second plurality of struts each extend radially along a second strut path from the proximal hub to one of a second plurality of strut intersections. In the second configuration, the first plurality of struts forms a depression in the expandable framework and the second plurality of struts extends into the depression.

Abstract: Systems and methods for tracking the position of a head-mounted display (HMD) system component. The HMD component may carry a plurality of angle sensitive detectors that are able to detect the angle of light emitted from a light source. The HMD component may include one or more scatter detectors that detect whether light has been scattered or reflected, so such light can be ignored. Control circuitry causes light sources to emit light according a specified pattern, and receives sensor data from the plurality of angle sensitive detectors. The processor may process the sensor data and scatter detector data, for example using machine learning or other techniques, to track a position of the HMD component. An angle sensitive detector may include a spatially-varying polarizer having a position-varying polarizing pattern and one or more polarizer layers that together are operative to detect the angle of impinging light.

Abstract: A head-mounted display device includes a display panel (such as a liquid crystal display), an optics system for focusing a portion of the display onto an eye of a user, and a backlight assembly including a light guide, a plurality of extraction features positioned on a surface of the light guide, and at least one laser diode for directing light into the light guide. The light guide is sized and dimensioned to illuminate only a portion of the display that is focused by the optics system; with the plurality of light extraction features configured to diffuse light toward the display panel for back illuminating the display panel.

Abstract: A method of manufacturing a medical implant for occluding a left atrial appendage may include cutting an expandable scaffold in a first configuration, wherein the expandable scaffold includes a plurality of struts having ends joined together at intersection points and a plurality of anchor members extending from the plurality of struts such that each anchor member extends from a medial portion of a strut of the plurality of struts, forming the expandable scaffold into a second configuration, wherein forming the expandable scaffold into the second configuration includes bending each anchor member along its bending axis, the bending axis being oriented parallel to a longitudinal axis of its respective strut of the plurality of struts, and heat setting the expandable scaffold in the second configuration. The method may include securing an occlusive element to the expandable scaffold.