Abstract: A spool configured to support a roll of material. The spool comprises an arbor, a first flange, and a second flange. The first flange includes a first plurality of flange panels that are rotatably connected to respective arbor panels of the arbor at a first arbor edge of the arbor. The second flange is connected to a second arbor edge of the arbor. The first flange is configured to transition between a retention configuration and an open configuration. In the retention configuration, the roll of material is substantially prevented from removal from the arbor along an arbor axis by the first and second flanges. In the open configuration, the roll of material is removable from the arbor and receivable on the arbor in the arbor direction.

Abstract: A magnetic toy figure includes a torso extending along a torso axis. The torso includes a first torso side, a second torso side opposite the first torso side, a base torso side extending between the first and second torso sides, and a head torso side extending between the first and second torso sides and spaced from the base torso side. The magnetic toy figure also includes a first arm coupled to the first torso side, a second arm coupled to said second torso side, a leg coupled to and extending away from the base torso side, and a head coupled to and extending away from the head torso side along the torso axis. The magnetic toy figure further includes a first magnet coupled to the first arm, a second magnet coupled to the second arm, a leg magnet coupled to the leg, and a head magnet coupled to said head.

Abstract: The disclosure provides the enzyme and non-enzyme replacement therapies for treating Fabry disease in a human subject, determined based on measuring the presence or absence of an anti-?-Galactosidase A (GLA) neutralizing antibody in a biological sample of the subject, as measured by an anti-GLA neutralizing antibody assay.

Abstract: Facilitating device compatibility is provided herein. A system can comprise a processor and a memory that stores executable instructions that, when executed by the processor, facilitate performance of operations. The operations can comprise evaluating a parameter of a device to a defined parameter of a device pool based on receipt of a request to add the device to the device pool and based on a determination that a device type of the device does not match a defined device type of the device pool. Further, the operations can comprise either allowing the device to be included in the device pool based on the evaluating, or denying the device to be included in the device pool based on the evaluating. If the inclusion of the device is denied, the operations can comprise providing information indicative of a denial to add the device to the device pool.

Abstract: Facilitating device compatibility is provided herein. A system can comprise a processor and a memory that stores executable instructions that, when executed by the processor, facilitate performance of operations. The operations can comprise evaluating a parameter of a device to a defined parameter of a device pool based on receipt of a request to add the device to the device pool and based on a determination that a device type of the device does not match a defined device type of the device pool. Further, the operations can comprise either allowing the device to be included in the device pool based on the evaluating, or denying the device to be included in the device pool based on the evaluating. If the inclusion of the device is denied, the operations can comprise providing information indicative of a denial to add the device to the device pool.

Abstract: A combination drinking cup and snack container includes a first body having a first cavity sized to hold liquid, and a second body coupled to the first body, the second body having a second cavity sized to hold food items. The combination drinking cup and snack container also includes a lid coupled to the second body, the lid having at least one flexible member that inhibits food items from spilling out of the second body.

Abstract: A snack container for holding food items. The container includes a main body and a lid coupled to the main body. The lid includes a first section having an interior rim defining an opening. The lid further includes a second section coupled to both the main body and the first section. The second section is affixed to the main body along a first portion of the second section and not affixed to the main body along a second portion of the second section.

Abstract: Provided herein are methods for generating diverse polypeptide and nucleic acid molecule libraries and collections, and the collections and libraries; methods for selecting variant polypeptides and nucleic acid molecules from the libraries; and molecules selected from the libraries. Exemplary of the polypeptides and nucleic acid molecules are antibodies and nucleic acids encoding the antibodies (including antibody fragments and domain exchanged antibodies). Also provided herein are methods of displaying polypeptides such as antibodies, for example on the surface of genetic packages, such as phage; and libraries and collections of the displayed polypeptides and vectors for producing the displayed polypeptides, libraries and collections. Exemplary of the displayed antibodies are domain exchanged antibodies.

Abstract: Provided herein are methods for generating diverse polypeptide and nucleic acid molecule libraries and collections, and the collections and libraries; methods for selecting variant polypeptides and nucleic acid molecules from the libraries; and molecules selected from the libraries. Exemplary of the polypeptides and nucleic acid molecules are antibodies and nucleic acids encoding the antibodies (including antibody fragments and domain exchanged antibodies). Also provided herein are methods of displaying polypeptides such as antibodies, for example on the surface of genetic packages, such as phage; and libraries and collections of the displayed polypeptides and vectors for producing the displayed polypeptides, libraries and collections. Exemplary of the displayed antibodies are domain exchanged antibodies.

Abstract: An applicator device for applying a substance to an area of the body that is difficult to reach includes a collapsible handle and a head portion rotatably mounted on one end. The head portion includes an attachment means, which can comprise either a field of hooks or a field of loops. The attachment means receives a two-sided pad engagement member that preferably has fields of loops or hooks on one side to engage the respective hooks or loops of the attachment member, and a field of hooks on its opposite side. The hooks of the pad engagement member can securely retain a pad that carries the substance to be applied to the body.

Abstract: The disclosure generally relates to paint applicators, and more particularly to paint applicators comprising a container having an opening, and a housing assembly removably attachable to the container, the housing assembly comprising a paint application element in fluid communication with a contents of the container.

Abstract: The disclosure generally relates to paint applicators, and more particularly to paint applicators comprising a container having an opening, and a housing assembly removably attached to the container, the housing assembly comprising a paint application element and a push-pull valve, the paint application element being adjacent to the push-pull valve, and the push-pull valve being in fluid communication with a contents of the container.