Abstract: An eyeglasses frame is disclosed that includes a left rim and a right rim. Each of the left rim and the right rim has a medial side and a temporal side. The temporal side of one of the left rim and the right rim has a lens mounting edge and a blind recess that extends from the lens mounting edge. The eyeglasses frame also includes a camera enclosure that is disposed on a posterior segment of the temporal side of one of the left rim and the right rim. The camera enclosure extends from a first end adjacent to the lens mounting edge to a second end disposed posterior of the posterior segment of the one of the left rim and the right rim. The second end of the camera enclosure has an observation aperture, wherein an image viewing axis disposed through the observation aperture is angled medially and upwardly.

Abstract: An eyeglasses frame is disclosed that includes a left rim and a right rim. Each of the left rim and the right rim has a medial side and a temporal side. The temporal side of one of the left rim and the right rim has a lens mounting edge and a blind recess that extends from the lens mounting edge. The eyeglasses frame also includes a camera enclosure that is disposed on a posterior segment of the temporal side of one of the left rim and the right rim. The camera enclosure extends from a first end adjacent to the lens mounting edge to a second end disposed posterior of the posterior segment of the one of the left rim and the right rim. The second end of the camera enclosure has an observation aperture, wherein an image viewing axis disposed through the observation aperture is angled medially and upwardly.

Abstract: A spectacles-mounted ophthalmic monitoring system may include a spectacles frame comprising a left rim and a right rim, an image sensor coupled with the spectacles frame to capture images of a field of view of an eye, and a processor. The processor may be configured to activate the image sensor to capture an image of the field of view, and identify a height of a tear film meniscus within the field of view of one or more images within the series of images.

Abstract: Engineered effector cells, such as chimeric antigen receptors (CARs), are used for enhanced immunogenic response to specific antigen, such as CD46. Disclosed herein are compositions and methods of treatment a cancer overexpressing CD46, which comprises a pharmaceutical composition comprising an engineered effector cell.

Abstract: A spectacles-mounted ophthalmic monitoring system may include a spectacles frame comprising a left rim and a right rim, an image sensor coupled with the spectacles frame to capture images of a field of view of an eye, and a processor. The processor may be configured to activate the image sensor to capture an image of the field of view, and identify a height of a tear film meniscus within the field of view of one or more images within the series of images.

Abstract: Engineered effector cells, such as chimeric antigen receptors (CARs), are used for enhanced immunogenic response to specific antigen, such as CD46. Disclosed herein are compositions and methods of treatment a cancer overexpressing CD46, which comprises a pharmaceutical composition comprising an engineered effector cell.

Abstract: The present invention provides ionic liquid-tolerant cellulases and method of producing and using such cellulases. The cellulases of the invention are useful in saccharification reactions using ionic liquid treated biomass.

Abstract: The present invention provides ionic liquid-tolerant cellulases and method of producing and using such cellulases. The cellulases of the invention are useful in saccharification reactions using ionic liquid treated biomass.

Abstract: The present invention provides ionic liquid-tolerant cellulases and method of producing and using such cellulases. The cellulases of the invention are useful in saccharification reactions using ionic liquid treated biomass.

Abstract: The invention discloses several types of fastener, fastening systems, fastener assemblies and related areas. In particular, the invention relates to a releasable fastening system (50) which has a pin (152) with a locking cavity (163). The pin is intended for insertion in an aperture (154). A locking means (158, 160) engages the locking cavity (163) of the pin (152) when the pin (152) is received in the aperture (154). The system (150) also includes unlocking means (162) which includes material adapted to contract when activated. When a material contracts, engagement means (158) included in the locking means (158, 160), disengage the locking cavity (154).

Abstract: Described herein are materials and methods useful for the treatment of neurodegenerative disorders in a subject. Materials described herein include polysaccharide digestive products resulting from the enzymatic hydrolysis of low acyl gellan gum.

Abstract: The invention discloses several types of fastener, fastening systems, fastener assemblies and related areas. In particular, the invention relates to a releasable fastening system (150) which has a pin (152) with a locking cavity (163). The pin is intended for insertion in an aperture (154). A locking means (158, 160) engages the locking cavity (163) of the pin (152) when the pin (152) is received in the aperture (154), The system (150) also includes unlocking means (162) which includes material adapted to contract when activated. When a material contracts, engagement means (158) included in the locking means (158, 160), disengage the locking cavity (154).

Abstract: The present invention provides ionic liquid-tolerant cellulases and method of producing and using such cellulases. The cellulases of the invention are useful in saccharification reactions using ionic liquid treated biomass.

Abstract: The invention discloses several types of fastener, fastening systems, fastener assemblies and related areas. In particular, the invention relates to a releasable fastening system (150) which has a pin (152) with a locking cavity (163). The pin is intended for insertion in an aperture (154). A locking means (158, 160) engages the locking cavity (163) of the pin (152) when the pin (152) is received in the aperture (154), The system (150) also includes unlocking means (162) which includes material adapted to contract when activated. When a material contracts, engagement means (158) included in the locking means (158, 160), disengage the locking cavity (154).

Abstract: A flow path is provided for a drip emitter to reduce the supply pressure in a manner reducing the potential for the flow path to become obstructed and clogged. The path employs a central path with a predetermined size and a series of baffles with predetermined spacing. The flow path further includes a metering chamber and a diaphragm to compensate for changes in supply pressure and an outlet that facilitates self-flushing in conjunction with the operation of the diaphragm.

Abstract: The invention discloses several types of fastener, fastening systems, fastener assmeblies and related areas. In particular, the invention discloses a releasable fastening system (150) which has a pin (152) with a locking cavity (163). The pin is intended for insertion in an aperture (154). A locking means (158, 160) engages the locking cavity (163) of the pin (152) when the pin (152) is received in the aperture (154). The system (150) also includes unlocking means (162) which includes material adapted to contract when activated. When a material contracts, engagement means (158) included in the locking means (158, 160), disengage the locking cavity (154).

Abstract: A flow path is provided for a drip emitter to reduce the supply pressure in a manner reducing the potential for the flow path to become obstructed and clogged. The path employs a central path with a predetermined size and a series of baffles with predetermined spacing. The flow path further includes a metering chamber and a diaphragm to compensate for changes in supply pressure and an outlet that facilitates self-flushing in conjunction with the operation of the diaphragm.

Abstract: The present invention provides chimeric polypeptides comprising a first polypeptide that binds to a component of extracellular matrix and a second polypeptide that provides for a therapeutic effect. The present invention further provides compositions, including pharmaceutical compositions, comprising a subject chimeric polypeptide. A subject chimeric polypeptide is useful in a variety of treatment, diagnostic, and research applications, which are also provided.