Abstract: A crimping tool is provided. The crimping tool includes a stationary jaw and a movable jaw. The movable jaw is arranged adjacent the stationary jaw, the movable jaw being movable from an open position to a closed position. A linkage is operably coupled to the movable jaw on one end, the linkage rotatable about an axle. A first input member is operably coupled to the linkage to rotate the linkage about the axle, the first input member rotating about a first axis. A second input member is operably coupled to the linkage to rotate the linkage about the axle, the second input member rotating about a second axis, the second axis being substantially perpendicular to the first axis.

Abstract: A crimping tool is provided which includes a movable jaw. The jaw being movable from an open and crimped positions. In an embodiment a linkage is coupled to the jaw and is rotatable about an axle. A member is provided having at least a first and second gear portion, the member pivoting about the linkage and moving relative to the main axle as the jaw moves from the open to the crimped position. A ring gear is coupled to the second gear portion and cooperate therewith to rotate the member about the axle. A drive gear rotates about the axle and cooperates with the first gear portion cooperating to rotate the member relative to the linkage. A handle is pivotally coupled to the axle. A drive pawl is coupled to the handle and rotates the drive gear in response to the handle moving from a first to a second position.

Abstract: A crimping tool is provided. The crimping tool includes a stationary jaw and a movable jaw. The movable jaw is arranged adjacent the stationary jaw, the movable jaw being movable from an open position to a closed position A linkage is operably coupled to the movable jaw on one end, the linkage rotatable about an axle. A first input member is operably coupled to the linkage to rotate the linkage about the axle, the first input member rotating about a first axis. A second input member is operably coupled to the linkage to rotate the linkage about the axle, the second input member rotating about a second axis, the second axis being substantially perpendicular to the first axis.

Abstract: A crimping tool is provided. The crimping tool includes a movable jaw. The jaw being movable from an open and crimped positions. In an embodiment a linkage is coupled to the jaw and is rotatable about an axle. A member is provided having at least a first and second gear portion, the member pivoting about the linkage and moving relative to the main axle as the jaw moves from the open to the crimped position. A ring gear is coupled to the second gear portion and cooperate therewith to rotate the member about the axle. A drive gear rotates about the axle and cooperates with the first gear portion cooperating to rotate the member relative to the linkage. A handle is pivotally coupled to the axle. A drive pawl is coupled to the handle and rotates the drive gear in response to the handle moving from a first to a second position.

Abstract: A immunoassay based on the detection of leukocyte-elastase produced fibrinogen cleavage peptides which allows the evaluation of the potency of compounds that inhibit formation of cleavage peptides in a variety of in vitro cell biological situations is provided. The assay may be employed to detect an endogenous leukocyte-elastase produced fibrinogen cleavage peptide signal in normal human plasma and at elevated levels in cystic fibrosis plasma and in rheumatoid arthritis synovial fluid samples. The assay procedure can be a single step assay which allows for the rapid and reproducible detection of specific cleavage peptides.