Abstract: A web-based server/cloud computing system for a next generation sequencer (NGS) to integrate data generation, data analysis and data management. When a user intends to sequence a biological sample, the user is asked to login to the NGSinForm, select and submits sets of software analysis bioinformatics programs, which schedules the sequencing, quality control, data analysis and management of that data, all done simultaneously and sequentially. When the sequencing is completed, the raw sequence data is uploaded to a server or cloud, raw data is analyzed, following the analysis preferences. Finally, all data generated will be saved and managed systematically. Hence, a user is able to access the information on the sample as well as the analyzed data anytime and anywhere with a one-time submission of the single web form—NGSinForm—even before starting the sequencing.