Abstract: The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions.

Abstract: The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.

Abstract: The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.

Abstract: Described herein are systems and methods for work from home solutions according to various embodiments of the invention. These solutions accurately diagnose connectivity issue locations and severity from any, some, or all points in a network framework. Embodiments of these solutions may also use artificial intelligence and machine learning to process customer quality-of-experience (QoE) feedback and other relevant indicators. The solutions may improve network connectivity based on these measurements and processes.

Abstract: The present invention relates to compositions comprising GLP-2 protein or variants thereof linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in the treatment of GLP-2 related conditions.

Abstract: Described herein are systems and methods for work from home solutions according to various embodiments of the invention. These solutions accurately diagnose connectivity issue locations and severity from any, some, or all points in a network framework. Embodiments of these solutions may also use artificial intelligence and machine learning to process customer quality-of-experience (QoE) feedback and other relevant indicators. The solutions may improve network connectivity based on these measurements and processes.

Abstract: The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.

Abstract: The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions.

Abstract: The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.

Abstract: Described herein are systems and methods for work from home solutions according to various embodiments of the invention. These solutions accurately diagnose connectivity issue locations and severity from any, some, or all points in a network framework. Embodiments of these solutions may also use artificial intelligence and machine learning to process customer quality-of-experience (QoE) feedback and other relevant indicators. The solutions may improve network connectivity based on these measurements and processes.

Abstract: Methods, techniques, computer program products, apparatus, devices, etc., used in connection with DSL Management Interfaces, significantly improve the management capabilities of a DSL network and/or improve testing relating to DSL equipment and services by permitting better control and operation of a DSL system, including implementation of timestamping for more accurate measurement, monitoring and control of a system. Timestamping further allows customized data collection techniques, where a DSL line can be measured or monitored at intervals whose frequency depends on the line's stability. Moreover, data parameter read and control parameter write operations are presented in conjunction with the use of timestamping. Also, control and operation of a DSL system is enhanced by implementing bit-loading that minimizes, eliminates or otherwise mitigates the amount by which the SNR margin per tone exceeds a maximum SNR margin quantity, where such bit-loading can be selected through an appropriate interface.

Abstract: Described herein are systems and methods for work from home solutions according to various embodiments of the invention. These solutions accurately diagnose connectivity issue locations and severity from any, some, or all points in a network framework. Embodiments of these solutions may also use artificial intelligence and machine learning to process customer quality-of-experience (QoE) feedback and other relevant indicators. The solutions may improve network connectivity based on these measurements and processes.

Abstract: This application relates to methods for determining the concentration of an odorant composition for use with an age-restricted product. The methods generally include creating an odor or flavor profile that may be used to either optimize flavors and odors to appeal to certain age groups, or to discourage use by certain age groups. In some instances, odorant compositions may be screened to determine whether they are differentially perceived by age groups.

Abstract: Described herein are systems and methods for work from home solutions according to various embodiments of the invention. These solutions accurately diagnose connectivity issue locations and severity from any, some, or all points in a network framework. Embodiments of these solutions may also use artificial intelligence and machine learning to process customer quality-of-experience (QoE) feedback and other relevant indicators. The solutions may improve network connectivity based on these measurements and processes.

Abstract: A system and method for relief of negative lung pressure during acute laryngospasm or upper airway obstruction, providing a non-toxic gas cartridge capable of supplying between 0.5-5 liters of gas during a procedure, a valve adapted to commence and stop gas release, and a trans-cricothyroid cartilage inflation needle for acutely relieving the negative pressure in the chest. The needle may also be used to insert a guidewire to assist in endotracheal tube insertion.

Abstract: The present invention relates to compositions comprising factor IX coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions.

Abstract: The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.

Abstract: The present disclosure provides nucleic acids and vectors for use with methanotrophic bacteria. Related host cells and methods for using such nucleic acids and vectors for expressing polypeptides or other genetic manipulation of methanotrophic bacteria are also provided.

Abstract: A system and method for relief of negative lung pressure during acute laryngospasm or upper airway obstruction, providing a non-toxic gas cartridge capable of supplying between 0.5-5 liters of gas during a procedure, a valve adapted to commence and stop gas release, and a trans-cricothyroid cartilage inflation needle for acutely relieving the negative pressure in the chest. The needle may also be used to insert a guidewire to assist in endotracheal tube insertion.

Abstract: The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions.