Patents by Inventor Joshua Silverman

Joshua Silverman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250051405
    Abstract: The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.
    Type: Application
    Filed: July 12, 2024
    Publication date: February 13, 2025
    Inventors: Volker Schellenberger, Joshua Silverman, Chia-Wei Wang, Benjamin Spink, Willem P. Stemmer, Nathan Geething, Wayne To, Jeffrey L. Cleland
  • Patent number: 12071456
    Abstract: The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.
    Type: Grant
    Filed: January 15, 2021
    Date of Patent: August 27, 2024
    Assignee: AMUNIX PHARMACEUTICALS, INC.
    Inventors: Volker Schellenberger, Joshua Silverman, Chia-wei Wang, Benjamin Spink, Willem P. Stemmer, Nathan Geething, Wayne To, Jeffrey L. Cleland
  • Publication number: 20240137291
    Abstract: Described herein are systems and methods for work from home solutions according to various embodiments of the invention. These solutions accurately diagnose connectivity issue locations and severity from any, some, or all points in a network framework. Embodiments of these solutions may also use artificial intelligence and machine learning to process customer quality-of-experience (QoE) feedback and other relevant indicators. The solutions may improve network connectivity based on these measurements and processes.
    Type: Application
    Filed: December 29, 2023
    Publication date: April 25, 2024
    Applicant: ASSIA SPE, LLC
    Inventors: John M. CIOFFI, Chan-Soo HWANG, Peter Joshua SILVERMAN, Tuncay CIL, Philip BEDNARZ, Peter CHOW, Carlos GARCIA HERNANDEZ
  • Publication number: 20240067695
    Abstract: The present invention relates to compositions comprising GLP-2 protein or variants thereof linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in the treatment of GLP-2 related conditions.
    Type: Application
    Filed: June 6, 2023
    Publication date: February 29, 2024
    Inventors: Volker SCHELLENBERGER, Joshua SILVERMAN, Willem P. STEMMER, Chia-wei WANG, Nathan GEETHING, Benjamin SPINK
  • Patent number: 11863403
    Abstract: Described herein are systems and methods for work from home solutions according to various embodiments of the invention. These solutions accurately diagnose connectivity issue locations and severity from any, some, or all points in a network framework. Embodiments of these solutions may also use artificial intelligence and machine learning to process customer quality-of-experience (QoE) feedback and other relevant indicators. The solutions may improve network connectivity based on these measurements and processes.
    Type: Grant
    Filed: August 3, 2022
    Date of Patent: January 2, 2024
    Assignee: ASSIA SPE, LLC
    Inventors: John M. Cioffi, Chan-Soo Hwang, Peter Joshua Silverman, Tuncay Cil, Philip Bednarz, Peter Chow, Carlos Garcia Hernandez
  • Publication number: 20230322900
    Abstract: The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.
    Type: Application
    Filed: December 12, 2022
    Publication date: October 12, 2023
    Inventors: Volker Schellenberger, Pei-Yun Chang, Fatbardha Varfaj, Sheng Ding, Joshua Silverman, Chia-wei Wang, Benjamin Spink, Willem P. Stemmer, Nathan Geething, John Kulman, Tongyao Liu, Garabet G. Toby, Haiyan Jiang, Robert Peters, Deping Wang, Baisong Mei
  • Publication number: 20230061715
    Abstract: The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions.
    Type: Application
    Filed: February 24, 2022
    Publication date: March 2, 2023
    Inventors: Volker SCHELLENBERGER, Joshua SILVERMAN, Chia-wei WANG, Benjamin SPINK, Willem P.C STEMMER, Nathan C. GEETHING
  • Publication number: 20230019286
    Abstract: The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.
    Type: Application
    Filed: April 26, 2021
    Publication date: January 19, 2023
    Inventors: Volker SCHELLENBERGER, Pei-Yun CHANG, Fatbardha VARFAJ, John KULMAN, Tongyao LIU, Garabet G. TOBY, Haiyan JIANG, Robert PETERS, Deping WANG, Baisong MEI, Joshua SILVERMAN, Chia-Wei WANG, Benjamin SPINK, Nathan GEETHING
  • Publication number: 20220400065
    Abstract: Described herein are systems and methods for work from home solutions according to various embodiments of the invention. These solutions accurately diagnose connectivity issue locations and severity from any, some, or all points in a network framework. Embodiments of these solutions may also use artificial intelligence and machine learning to process customer quality-of-experience (QoE) feedback and other relevant indicators. The solutions may improve network connectivity based on these measurements and processes.
    Type: Application
    Filed: August 3, 2022
    Publication date: December 15, 2022
    Applicant: ASSIA SPE, LLC
    Inventors: John M. CIOFFI, Chan-Soo HWANG, Peter Joshua SILVERMAN, Tuncay CIL, Philip BEDNARZ, Peter CHOW, Carlos GARCIA HERNANDEZ
  • Patent number: 11477081
    Abstract: Methods, techniques, computer program products, apparatus, devices, etc., used in connection with DSL Management Interfaces, significantly improve the management capabilities of a DSL network and/or improve testing relating to DSL equipment and services by permitting better control and operation of a DSL system, including implementation of timestamping for more accurate measurement, monitoring and control of a system. Timestamping further allows customized data collection techniques, where a DSL line can be measured or monitored at intervals whose frequency depends on the line's stability. Moreover, data parameter read and control parameter write operations are presented in conjunction with the use of timestamping. Also, control and operation of a DSL system is enhanced by implementing bit-loading that minimizes, eliminates or otherwise mitigates the amount by which the SNR margin per tone exceeds a maximum SNR margin quantity, where such bit-loading can be selected through an appropriate interface.
    Type: Grant
    Filed: January 15, 2020
    Date of Patent: October 18, 2022
    Assignee: ASSIA SPE, LLC
    Inventors: John Cioffi, Wonjong Rhee, Sumanth Jagannathan, Peter Joshua Silverman, Mehdi Mohseni, Georgios Ginis
  • Patent number: 11411840
    Abstract: Described herein are systems and methods for work from home solutions according to various embodiments of the invention. These solutions accurately diagnose connectivity issue locations and severity from any, some, or all points in a network framework. Embodiments of these solutions may also use artificial intelligence and machine learning to process customer quality-of-experience (QoE) feedback and other relevant indicators. The solutions may improve network connectivity based on these measurements and processes.
    Type: Grant
    Filed: April 6, 2021
    Date of Patent: August 9, 2022
    Assignee: ASSIA SPE, LLC
    Inventors: John M. Cioffi, Chan-Soo Hwang, Peter Joshua Silverman, Tuncay Cil, Philip Bednarz, Peter Chow, Carlos Garcia Hernandez
  • Publication number: 20220110886
    Abstract: This application relates to methods for determining the concentration of an odorant composition for use with an age-restricted product. The methods generally include creating an odor or flavor profile that may be used to either optimize flavors and odors to appeal to certain age groups, or to discourage use by certain age groups. In some instances, odorant compositions may be screened to determine whether they are differentially perceived by age groups.
    Type: Application
    Filed: December 20, 2021
    Publication date: April 14, 2022
    Inventors: Joshua SILVERMAN, Morgan Z. MONCADA, William E.C. HARRIES
  • Publication number: 20210314238
    Abstract: Described herein are systems and methods for work from home solutions according to various embodiments of the invention. These solutions accurately diagnose connectivity issue locations and severity from any, some, or all points in a network framework. Embodiments of these solutions may also use artificial intelligence and machine learning to process customer quality-of-experience (QoE) feedback and other relevant indicators. The solutions may improve network connectivity based on these measurements and processes.
    Type: Application
    Filed: April 6, 2021
    Publication date: October 7, 2021
    Applicant: ASSIA SPE, LLC
    Inventors: John M. CIOFFI, Chan-Soo HWANG, Peter Joshua SILVERMAN, Tuncay CIL, Philip BEDNARZ, Peter CHOW, Carlos GARCIA HERNANDEZ
  • Publication number: 20210299382
    Abstract: A system and method for relief of negative lung pressure during acute laryngospasm or upper airway obstruction, providing a non-toxic gas cartridge capable of supplying between 0.5-5 liters of gas during a procedure, a valve adapted to commence and stop gas release, and a trans-cricothyroid cartilage inflation needle for acutely relieving the negative pressure in the chest. The needle may also be used to insert a guidewire to assist in endotracheal tube insertion.
    Type: Application
    Filed: June 14, 2021
    Publication date: September 30, 2021
    Inventors: Mark Stewart, Richard Kollmar, Krishnamurthi Sundaram, Joshua Silverman, Ko Nakase, Hamid Arjomandi
  • Publication number: 20210277074
    Abstract: The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.
    Type: Application
    Filed: January 15, 2021
    Publication date: September 9, 2021
    Inventors: Volker Schellenberger, Joshua Silverman, Chia-wei Wang, Benjamin Spink, Willem P. Stemmer, Nathan Geething, Wayne To, Jerrfey L. Cleland
  • Publication number: 20210277378
    Abstract: The present invention relates to compositions comprising factor IX coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of coagulation factor-related diseases, disorders, and conditions.
    Type: Application
    Filed: January 19, 2021
    Publication date: September 9, 2021
    Inventors: Volker SCHELLENBERGER, Willem P. STEMMER, Nathan C. GEETHING, Wayne TO, Joshua SILVERMAN, Chia-wei WANG, Benjamin SPINK
  • Patent number: 11041159
    Abstract: The present disclosure provides nucleic acids and vectors for use with methanotrophic bacteria. Related host cells and methods for using such nucleic acids and vectors for expressing polypeptides or other genetic manipulation of methanotrophic bacteria are also provided.
    Type: Grant
    Filed: August 28, 2019
    Date of Patent: June 22, 2021
    Assignee: Calysta, Inc.
    Inventors: Renee M. Saville, Joshua Silverman, Jeremy Minshull, Jon Edward Ness, Effendi Leonard, Jana Stumpe, Mark Welch
  • Patent number: 11033702
    Abstract: A system and method for relief of negative lung pressure during acute laryngospasm or upper airway obstruction, providing a non-toxic gas cartridge capable of supplying between 0.5-5 liters of gas during a procedure, a valve adapted to commence and stop gas release, and a trans-cricothyroid cartilage inflation needle for acutely relieving the negative pressure in the chest. The needle may also be used to insert a guidewire to assist in endotracheal tube insertion.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: June 15, 2021
    Assignee: The Research Foundation for the State University of New York
    Inventors: Mark Stewart, Richard Kollmar, Krishnamurthi Sundaram, Joshua Silverman, Ko Nakase, Hamid Arjomandi
  • Publication number: 20210164011
    Abstract: The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions.
    Type: Application
    Filed: September 29, 2020
    Publication date: June 3, 2021
    Inventors: Volker Schellenberger, Joshua Silverman, Chia-wei Wang, Benjamin Spink, Willem P.C. Stemmer, Nathan C. Geething
  • Patent number: 10961287
    Abstract: The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: March 30, 2021
    Assignee: Amunix Pharmaceuticals, Inc
    Inventors: Volker Schellenberger, Joshua Silverman, Chia-wei Wang, Benjamin Spink, Willem P. Stemmer, Nathan Geething, Wayne To, Jeffrey L. Cleland