Patents by Inventor Joshua Spector Tullis

Joshua Spector Tullis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isoxazolone compounds useful in treating diseases associated with unwanted cytokine activity
    Patent number: 6919346
    Abstract: Isoxazolone compounds having the generic structure: are used to treat disease associated with unwanted cytokine activity, including rheumatoid arthritis, osteoarthritis, diabetes, HIV/AIDS, inflammatory bowel disease, Crohn's disease, ulcerative colitis, congestive heart, hypertension, chronic obstructive pulmonary disease, septic shock syndrome, tuberculosis, adult respiratory distress, asthma, atherosclerosis, muscle degeneration, periodontal disease, cachexia, Reiter's syndrome, gout, acute synovitis, anorexia and bulimia nervosa fever, malaise, myalgia and headaches.
    Type: Grant
    Filed: December 2, 2003
    Date of Patent: July 19, 2005
    Assignee: The Procter & Gamble Company
    Inventors: Michael Philip Clark, Jane Far-Jine Djung, Steven Karl Laughlin, Joshua Spector Tullis, Michael George Natchus, Biswanath De
  • Isoxazolone compounds useful in treating diseases associated with unwanted cytokine activity
    Patent number: 6790846
    Abstract: Isoxazolone compounds having the generic structure: are used to treat disease associated with unwanted cytokine activity, including rheumatoid arthritis, osteoarthritis, diabetes, HIV/AIDS, inflammatory bowel disease, Crohn's disease, ulcerative colitis, congestive heart, hypertension, chronic obstructive pulmonary disease, septic shock syndrome, tuberculosis, adult respiratory distress, asthma, atherosclerosis, muscle degeneration, periodontal disease, cachexia, Reiter's syndrome, gout, acute synovitis, anorexia and bulimia nervosa fever, malaise, myalgia and headaches.
    Type: Grant
    Filed: May 7, 2002
    Date of Patent: September 14, 2004
    Assignee: The Procter & Gamble Company
    Inventors: Michael Philip Clark, Jane Far-Jine Djung, Steven Karl Laughlin, Joshua Spector Tullis, Michael George Natchus, Biswanath De
  • Triazole compounds useful in treating diseases associated with unwanted cytokine activity
    Patent number: 6787555
    Abstract: The present invention relates to 4-aryl triazoles having the formula: wherein R1 is independently selected from the group consisting of: lower alkyl, lower alkenyl, lower alkynyl, lower heteroalkyl, lower heteroalkenyl, lower heteroalkynyl, heterocycloalkyl, heteroaryl, halo, CN, OR4, SR4, S(O)R4, S(O)2R4, and NR4R5; and Q is has the general formula: said compounds are useful in treating diseases associated with unwanted cytokine activity, inter alia, interleukin-1 (IL-1) and tumor necrosis factor (TNF) from cells.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: September 7, 2004
    Assignee: The Procter & Gamble Company
    Inventors: Joshua Spector Tullis, John Charles Van Rens, Michael Philip Clark, Benjamin Eric Blass, Michael George Natchus, Biswanath De
  • Isoxazolone compounds useful in treating diseases associated with unwanted cytokine activity
    Publication number: 20040122025
    Abstract: Isoxazolone compounds having the generic structure: 1
    Type: Application
    Filed: December 2, 2003
    Publication date: June 24, 2004
    Applicant: The Procter & Gamble Company
    Inventors: Michael Philip Clark, Jane Far-Jine Djung, Steven Karl Laughlin, Joshua Spector Tullis, Michael George Natchus, Biswanath De
  • Triazole compounds useful in treating diseases associated with unwanted cytokine activity
    Patent number: 6727364
    Abstract: The present invention relates to 4-aryl triazoles having the formula: wherein R1 is independently selected from the group consisting of: lower alkyl, lower alkenyl, lower alkynyl, lower heteroalkyl, lower heteroalkenyl, lower heteroalkynyl, heterocycloalkyl, heteroaryl, halo, CN, OR4, SR4, S(O)R4, S(O)2R4, and NR4R5; and Q is has the general formula: said compounds are useful in treating diseases associated with unwanted cytokine activity, inter alia, interleukin-1 (IL-1) and tumor necrosis factor (TNF) from cells.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: April 27, 2004
    Assignee: The Procter & Gamble Company
    Inventors: Joshua Spector Tullis, John Charles Van Rens, Michael Philip Clark, Benjamin Eric Blass, Michael George Natchus, Biswanath De
  • Carbocyclic side chain containing metalloprotease inhibitors
    Publication number: 20030162778
    Abstract: The compounds have a structure according to the following Formula (I): 1
    Type: Application
    Filed: September 18, 2002
    Publication date: August 28, 2003
    Applicant: The Procter and Gamble Company
    Inventors: Michael George Natchus, Stanislaw Pikul, Neil Gregory Almstead, Matthew John Laufersweiler, Roger Gunnard Bookland, Joshua Spector Tullis, Biswanath De
  • Triazole compounds useful in treating diseases associated with unwanted cytokine activity
    Publication number: 20030100558
    Abstract: The present invention relates to 4-aryl triazoles having the formula: 1
    Type: Application
    Filed: April 24, 2002
    Publication date: May 29, 2003
    Inventors: Joshua Spector Tullis, John Charles Van Rens, Michael Philip Clark, Benjamin Eric Blass, Michael George Natchus, Biswanath De
  • Isoxazolone compounds useful in treating diseases associated with unwanted cytokine activity
    Publication number: 20030096814
    Abstract: Isoxazolone compounds having the generic structure: 1
    Type: Application
    Filed: May 7, 2002
    Publication date: May 22, 2003
    Inventors: Michael Philip Clark, Jane Far-Jine Djung, Steven Karl Laughlin, Joshua Spector Tullis, Michael George Natchus, Biswanath De
  • Triazole compounds useful in treating diseases associated with unwanted cytokine activity
    Publication number: 20030013712
    Abstract: The present invention relates to 4-aryl triazoles having the formula: 1
    Type: Application
    Filed: April 24, 2002
    Publication date: January 16, 2003
    Inventors: Joshua Spector Tullis, John Charles Van Rens, Michael Philip Clark, Benjamin Eric Blass, Michael George Natchus, Biswanath De