Abstract: Systems and methods are described that operate to manipulate networked applications and resources. A server is configured to extract a command from an Email message directed by a user to a predetermined address. A parser extracts parameters from the Email message, where the parameters configure and direct command execution. Parameters may be found in one or more fields of the Email message. The server responds to the command by manipulating an operational aspect of an application associated with the user and executed on a second, networked server. The command may be one of a set of commands maintained by the server. The server may maintain a customized set of commands for each registered user and default commands for unregistered users. Customized sets of commands may include commands created by the registered user.