Patents by Inventor Joshua USHER

Joshua USHER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF CELL-FREE CIRCULATING RNA (cfRNA) EXPRESSION OF PD-L1 AND ERCC1 IN PLASMA TO MONITOR RESPONSE TO THERAPY IN NSCLC
    Publication number: 20200377955
    Abstract: Quantitative levels of ERCC1 cfRNA are used to monitor/predict a clinical response with respect to a disease state of a cancer in a patient subject to treatment with a platinum-based drug. Most typically, the cancer is a NSCLC and the patient is treated with a platinum-based drug. Where treatment also includes immune checkpoint inhibitors, PD-L1 cfRNA may be quantified to further predict treatment outcome.
    Type: Application
    Filed: June 19, 2018
    Publication date: December 3, 2020
    Inventors: Kathleen DANENBERG, Joshua USHER, Shahrooz RABIZADEH
  • LIQUID BIOPSY FOR cfRNA
    Publication number: 20200102618
    Abstract: cfRNA is used to identify and quantitate expression levels of disease related genes and further allows for non-invasive monitoring of changes in such genes. Moreover, quantitative analysis of disease related genes will enable prediction of treatment response where the treatment is dependent on the presence of the disease related gene.
    Type: Application
    Filed: March 15, 2018
    Publication date: April 2, 2020
    Inventors: Kathleen DANENBERG, Shahrooz RABIZADEH, Joshua USHER, Yolanda JAIMES