Abstract: An exhaust hood for an axial steam turbine that includes a radial channel, downstream from the normal flow pattern. The radial channel guides the exhaust steam flow in upper half of the hood in the flow momentum direction. Due to this pattern of flow direction, vortex generation in upper exhaust hood is reduced and increased flow diffusion results. The geometric arrangement can eliminate the outer casing of the exhaust hood over the axial length of the turbine inner casing, allowing the turbine inner casing to be supported directly by a foundation for the steam turbine.

Abstract: A cover of an airfoil having opposing pressure and suction sides of a rotatable turbine stage to prevent fluid from crossover-flowing from a pressure side of a leading airfoil to a suction side of a trailing airfoil is provided. The cover includes pressure and suction side edge portions, one of which having a shape that is discontinuous relative to that of a complementary one of suction and pressure side edge portions of an aft cover of a corresponding one of a trailing and a leading airfoil, respectively.

Abstract: A turbomachine includes a housing having an inner surface, a compressor, a turbine and a rotary member including a plurality of blade members configured as part of one of the compressor and the turbine. Each of the plurality of blade members includes a base portion and a tip portion. The turbomachine also includes a honeycomb seal member mounted to the inner surface of the housing adjacent the rotary member. The honeycomb seal member includes a contoured surface having formed therein a deformation zone. The deformation zone includes an inlet zone and an outlet zone. The inlet zone is spaced a first distance from the tip portion of each of the plurality of blade members and the outlet zone is spaced a second distance from the tip portion of each of the plurality of blade members. The second distance being substantially equal to or less than the first distance.

Abstract: An apparatus is provided and includes a first member with a flow diverting member extending from a surface thereof and a second member disposed proximate to the first member with a clearance gap area defined between a surface of the second member and a distal end of the flow diverting member such that a fluid path, along which fluid flows from an upstream section and through the clearance gap area, is formed between the surfaces of the first and second members. The second member is formed to define dual vortex chambers at the upstream section in which the fluid is directed to flow in vortex patterns prior to being permitted to flow through the clearance gap area.

Abstract: The invention provides compositions and methods for treatment of sleep disorders. Such methods entail administering to the patient a therapeutically effective dosage regime of an agonist of a hypocretin 1 (Hcrt-1) receptor to a peripheral tissue of the patient, and monitoring the condition of the patient responsive to the treatment, wherein the monitoring indicates a reduction in excessive daytime sleepiness (EDS) and an improvement in nighttime sleep consolidation and architecture. The methods are particularly useful for prophylactic and therapeutic treatment of one or more sleep disorders in a patient.

Abstract: The invention provides compositions and methods for treatment of sleep disorders. Such methods entail administering to the patient a therapeutically effective dosage regime of an agonist of a hypocretin 1 (Hcrt-1) receptor to a peripheral tissue of the patient, and monitoring the condition of the patient responsive to the treatment, wherein the monitoring indicates a reduction in excessive daytime sleepiness (EDS) and an improvement in nighttime sleep consolidation and architecture. The methods are particularly useful for prophylactic and therapeutic treatment of one or more sleep disorders in a patient.

Abstract: The invention provides compositions and methods for treatment of sleep disorders. Such methods entail administering to the patient a therapeutically effective dosage regime of an agonist of a hypocretin 1 (Hcrt-1) receptor to a peripheral tissue of the patient, and monitoring the condition of the patient responsive to the treatment, wherein the monitoring indicates a reduction in excessive daytime sleepiness (EDS) and an improvement in nighttime sleep consolidation and architecture. The methods are particularly useful for prophylactic and therapeutic treatment of one or more sleep disorders in a patient.