Patents by Inventor Jost Enninga

Jost Enninga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Single cell based reporter assay to monitor gene expression patterns with high spatio-temporal resolution
    Patent number: 9663833
    Abstract: The invention relates to a double-stranded polynucleotide comprising on its positive strand considered from its 5? end to its 3? end, (i) a promoter of a gene of interest or several promoters of various genes of interest selected among genes which are endogenous to a determined cell, and, (ii) one or several barcode(s) wherein each barcode contains at least one barcode unit formed of at least one, especially of multiple, recognition binding sites each binding site being composed of a nucleotide sequence, and wherein each of said barcode(s) is under the control of at least one of said promoter(s) for transcription. It further concerns use of said polynucleotide to monitor gene expression patterns in living cells, especially in single cells, with a rapid and high spatio-temporal resolution.
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: May 30, 2017
    Assignee: INSTITUT PASTEUR
    Inventors: Musa Mhlanga, Jost Enninga, Philippe Sansonetti, Ulf Nehrbass
  • SINGLE CELL BASED REPORTER ASSAY TO MONITOR GENE EXPRESSION PATTERNS WITH HIGH SPATIO-TEMPORAL RESOLUTION
    Publication number: 20110021369
    Abstract: The invention relates to a double-stranded polynucleotide comprising on its positive strand considered from its 5? end to its 3? end, (i) a promoter of a gene of interest or several promoters of various genes of interest selected among genes which are endogenous to a determined cell, and, (ii) one or several barcode(s) wherein each barcode contains at least one barcode unit formed of at least one, especially of multiple, recognition binding sites each binding site being composed of a nucleotide sequence, and wherein each of said barcode(s) is under the control of at least one of said promoter(s) for transcription. It further concerns use of said polynucleotide to monitor gene expression patterns in living cells, especially in single cells, with a rapid and high spatio-temporal resolution.
    Type: Application
    Filed: September 12, 2008
    Publication date: January 27, 2011
    Applicant: INSTITUT PASTEUR
    Inventors: Musa Mhlanga, Jost Enninga, Philippe Sansonetti, Ulf Nehrbass