Patents by Inventor Jostein Holtlund
Jostein Holtlund has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11428686Abstract: Provided herein is technology relating to methods for assaying a cell-containing body sample and particularly, but not exclusively, to treating a sample under conditions to cause cell lysis, preferably by means of a detergent; and subjecting the lysed sample to conditions causing the cleavage of nucleic acid molecules. The technology additionally relates to using nucleic acid cleavage conditions to enhance a membrane assay, a device for carrying out such an assay, and a kit for use in the assay.Type: GrantFiled: January 10, 2018Date of Patent: August 30, 2022Assignee: ABBOTT RAPID DIAGNOSTICS INTERNATIONAL UNLIMITED COMPANYInventors: Jostein Holtlund, Andrew Campbell, Stig Morten Borch
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Publication number: 20180143183Abstract: The present invention provides an assay method for a cell-containing body sample, said method comprising treating said sample under conditions whereby to cause cell lysis, preferably by means of a detergent; and subjecting the thus-generated lysed sample to conditions causing the cleavage of nucleic acid molecules. The invention additionally provides the use of nucleic acid cleavage conditions in enhancing a membrane assay, a device for carrying out such an assay, and a kit for use in the assay.Type: ApplicationFiled: January 10, 2018Publication date: May 24, 2018Inventors: Jostein HOLTLUND, Andrew CAMPBELL, Morten BORCH
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Patent number: 9897594Abstract: The present invention provides an assay method for a cell-containing body sample, the method comprising treating the sample under conditions whereby to cause cell lysis, preferably by means of a detergent; and subjecting the thus-generated lysed sample to conditions causing the cleavage of nucleic acid molecules. The invention additionally provides the use of nucleic acid cleavage conditions in enhancing a membrane assay, a device for carrying out such an assay, and a kit for use in the assay.Type: GrantFiled: October 31, 2006Date of Patent: February 20, 2018Assignee: AXIS-SHIELD ASAInventors: Jostein Holtlund, Andrew Campbell, Morten Borch
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Patent number: 9140694Abstract: An assay apparatus comprising: i) an assay cartridge (52, 53) comprising at least one well (57-62) and a pipette (50) positionable in at least one said well; ii) a holder arranged to received said cartridge; iii) drive means operable to position said pipette in selected wells of said cartridge; iv) a gas pressure applicator couplable to said pipette whereby to cause liquid flow through said membrane; and v) a radiation detector operable to detect radiation from a well of said cartridge of said cartridge or from said pipette.Type: GrantFiled: August 29, 2013Date of Patent: September 22, 2015Assignee: AXIS-SHIELD ASAInventors: Jostein Holtlund, Stig Morten Borch, Thorstein Seim, Tore Janson, Hege Ton, Jan Roger Karlson, Inger Lise Lauvstad
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Publication number: 20140065646Abstract: An assay apparatus comprising: i) an assay cartridge (52, 53) comprising at least one well (57-62) and a pipette (50) positionable in at least one said well; ii) a holder arranged to received said cartridge; iii) drive means operable to position said pipette in selected wells of said cartridge; iv) a gas pressure applicator couplable to said pipette whereby to cause liquid flow through said membrane; and v) a radiation detector operable to detect radiation from a well of said cartridge of said cartridge or from said pipette.Type: ApplicationFiled: August 29, 2013Publication date: March 6, 2014Applicant: Axis-Shield ASInventors: Jostein HOLTLUND, Stig Morten BORCH, Thorstein SEIM, Tore JANSON, Hege TON, Jan Roger KARLSON, Inger Lise LAUVSTAD
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Patent number: 8545756Abstract: An assay apparatus comprising: i) an assay cartridge (52, 53) comprising at least one well (57-62) and a pipette (50) positionable in at least one said well; ii) a holder arranged to received said cartridge; iii) drive means operable to position said pipette in selected wells of said cartridge; iv) a gas pressure applicator couplable to said pipette whereby to cause liquid flow through said membrane; and v) a radiation detector operable to detect radiation from a well of said cartridge of said cartridge or from said pipette.Type: GrantFiled: September 14, 2012Date of Patent: October 1, 2013Assignee: Axis-Shield ASAInventors: Jostein Holtlund, Stig Morten Borch, Thorstein Seim, Tore Janson, Hege Tøn, Jan Roger Karlson, Inger Lise Lauvstad
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Publication number: 20130065256Abstract: An assay apparatus comprising: i) an assay cartridge (52, 53) comprising at least one well (57-62) and a pipette (50) positionable in at least one said well; ii) a holder arranged to received said cartridge; iii) drive means operable to position said pipette in selected wells of said cartridge; iv) a gas pressure applicator couplable to said pipette whereby to cause liquid flow through said membrane; and v) a radiation detector operable to detect radiation from a well of said cartridge of said cartridge or from said pipette.Type: ApplicationFiled: September 14, 2012Publication date: March 14, 2013Applicant: AXIS-SHIELD ASInventors: Jostein HOLTLUND, Stig Morten Borch, Thorstein Seim, Tore Janson, Hege Tøn, Jan Roger Karlson, Inger Lise Lauvstad
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Patent number: 8293175Abstract: An assay apparatus comprising: i) an assay cartridge (52, 53) comprising at least one well (57-62) and a pipette (50) positionable in at least one said well; ii) a holder arranged to receive said cartridge; iii) drive means operable to position said pipette in selected wells of said cartridge; iv) a gas pressure applicator couplable to said pipette whereby to cause liquid flow through said membrane; and v) a radiation detector operable to detect radiation from a well of said cartridge or from said pipette.Type: GrantFiled: November 13, 2009Date of Patent: October 23, 2012Assignee: Axis-Shield ASAInventors: Jostein Holtlund, Stig Morten Borch, Thorstein Seim, Tore Janson, Hege Tøn, Jan Roger Karlson, Inger Lise Lauvstad
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Publication number: 20100159487Abstract: An assay apparatus comprising: i) an assay cartridge (52, 53) comprising at least one well (57-62) and a pipette (50) positionable in at least one said well; ii) a holder arranged to receive said cartridge; iii) drive means operable to position said pipette in selected wells of said cartridge; iv) a gas pressure applicator couplable to said pipette whereby to cause liquid flow through said membrane; and v) a radiation detector operable to detect radiation from a well of said cartridge or from said pipette.Type: ApplicationFiled: November 13, 2009Publication date: June 24, 2010Applicant: AXIS-SHIELD ASAInventors: Jostein Holtlund, Stig Morten Borch, Thorstein Seim, Tore Janson, Hege Tøn, Jan Roger Karlson, Inger Lise Lauvstad
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Patent number: 7632462Abstract: An assay apparatus comprising: i) an assay cartridge (52,53) comprising at least one well (57-62) and a pipette (50) positionable in at least one said well; ii) a holder arranged to receive said cartridge; iii) drive means operable to position said pipette in selected wells of said cartridge; iv) a gas pressure applicator couplable to said pipette whereby to cause liquid flow through said membrane; and v) a radiation detector operable to detect radiation from a well of said cartridge or from said pipette.Type: GrantFiled: May 9, 2002Date of Patent: December 15, 2009Assignee: Axis-Shield ASAInventors: Jostein Holtlund, Stig Morten Borch, Thorstein Seim, Tore Janson, Hege Tøn, Jan Roger Karlson, Inger Lise Lauvstad
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Publication number: 20090220957Abstract: The present invention provides an assay method for a cell-containing body sample, said method comprising treating said sample under conditions whereby to cause cell lysis, preferably by means of a detergent; and subjecting the thus-generated lysed sample to conditions causing the cleavage of nucleic acid molecules. The invention additionally provides the use of nucleic acid cleavage conditions in enhancing a membrane assay, a device for carrying out such an assay, and a kit for use in the assay.Type: ApplicationFiled: October 31, 2006Publication date: September 3, 2009Applicant: AXIS-SHIELD ASAInventors: Jostein Holtlund, Andrew Campbell, Morten Borch
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Patent number: 7374943Abstract: The invention provides a kit for a glycated haemoglobin assay, said kit comprising: a porous membrane capable of retaining precipitated haemoglobin; a first reagent comprising zinc ions in aqueous basic solution or comprising a water soluble zinc compound; a second reagent comprising a chromophore-boronic acid conjugate; and optionally, an aqueous washing reagent; wherein at least one of the first and second reagents further comprises a surfactant capable of lysing erythrocytes, and wherein said second reagent if liquid is acidic.Type: GrantFiled: April 10, 2002Date of Patent: May 20, 2008Assignee: Axis-Shield USAInventors: Jostein Holtlund, Kerstin Bernström, Ellen Dworsky, Lise Corneliussen
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Publication number: 20040161368Abstract: An assay apparatus comprising: i) an assay cartridge (52, 53) comprising at least one well (57-62) and a pipette (50) positionable in at least one said well; ii) a holder arranged to receive said cartridge; iii) drive means operable to position said pipette in selected wells of said cartridge; iv) a gas pressure applicator couplable to said pipette whereby to cause liquid flow through said membrane; and v) a radiation detector operable to detect radiation from a well of said cartridge or from said pipette.Type: ApplicationFiled: April 9, 2004Publication date: August 19, 2004Inventors: Jostein Holtlund, Stig Morten Borch, Thorstein Seim, Tore Janson, Hege Ton, Jan Roger Karlson, Inger Lise Lauvstad
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Publication number: 20040137641Abstract: The invention provides a kit for a glycated haemoglobin assay, said kit comprising: a porous membrane capable of retaining precipitated haemoglobin; a first reagent comprising zinc ions in aqueous basic solution or comprising a water soluble zinc compound; a second reagent comprising a chromophore-boronic acid conjugate; and optionally, an aqueous washing reagent; wherein at least one of the first and second reagents further comprises a surfactant capable of lysing erythrocytes, and wherein said second reagent if liquid is acidic.Type: ApplicationFiled: February 26, 2004Publication date: July 15, 2004Inventors: Jostein Holtlund, Kerstin Bernstrom, Ellen Dworsky, Lise Corneliussen
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Patent number: 5691207Abstract: Methods of assaying samples for the presence of an analyte involving immobilization of a gold sol, and optionally an enzyme capable of generating a reaction product, on a solid phase. The gold sol has a mean particle size of less than 20 nm for at least 75% by weight of the particles and is formed into a novel superaggregated complex with at least one protein.Type: GrantFiled: April 29, 1993Date of Patent: November 25, 1997Assignee: Nycomed Pharma ASInventors: Jostein Holtlund, Geir Olav Gogstad
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Patent number: 5650333Abstract: Methods of assaying samples for the presence or quantity of an analyte involving immobilization of a gold sol, and optionally an enzyme capable of generating a reaction product, on a solid phase. The gold sol has a mean particle size of less than 20 nm for at least 75% by weight of the particles and is formed into a novel superaggregated complex with at least one protein.Type: GrantFiled: June 7, 1995Date of Patent: July 22, 1997Assignee: Nycomed Pharma ASInventors: Jostein Holtlund, Geir Olav Gogstad