Patents by Inventor Jovan Nikolic

Jovan Nikolic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutated Glycoprotein of Vesicular Stomatitis Virus
    Publication number: 20260078150
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Application
    Filed: September 5, 2025
    Publication date: March 19, 2026
    Inventors: Aurélie Albertini, Yves Gaudin, Hèlène Raux, Laura Belot, Jovan Nikolic
  • Mutated glycoprotein of vesicular stomatitis virus
    Patent number: 12410215
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Grant
    Filed: February 14, 2025
    Date of Patent: September 9, 2025
    Assignees: Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay
    Inventors: Aurélie Albertini, Yves Gaudin, Hélène Raux, Laura Belot, Jovan Nikolic
  • Mutated glycoprotein of vesicular stomatitis virus
    Patent number: 12410216
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Grant
    Filed: February 14, 2025
    Date of Patent: September 9, 2025
    Assignees: Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay
    Inventors: Aurélie Albertini, Yves Gaudin, Hélène Raux, Laura Belot, Jovan Nikolic
  • MYELOID CELLS MODIFIED BY CHIMERIC ANTIGEN RECEPTOR AND USES THEREOF FOR ANTI-CANCER THERAPY
    Publication number: 20250241949
    Abstract: A modified myeloid cell comprises a chimeric antigen receptor (CAR), or a modified induced pluripotent stem cell (iPS) or hematopoietic stem cell (HSC) comprising a CAR, wherein said CAR comprises an extracellular antigen-binding domain which binds to a tumor antigen or a tumor microenvironment (TME) antigen; a transmembrane domain; and a first intracellular signaling domain comprising the CD40 cytotail, which is fused to a second intracellular signaling domain comprising the CD3zeta intracellular domain. Therapeutic uses of the modified myeloid cell are disclosed.
    Type: Application
    Filed: April 7, 2023
    Publication date: July 31, 2025
    Inventors: Philippe BENAROCH, Jovan NIKOLIC
  • MYELOID CELLS MODIFIED BY CHIMERIC ANTIGEN RECEPTOR WITH CD40 AND USES THEREOF FOR ANTI-CANCER THERAPY
    Publication number: 20250222106
    Abstract: A modified myeloid cell comprises a chimeric antigen receptor (CAR), or a modified induced pluripotent stem cell (iPS) or hematopoietic stem cell (HSC) comprising a CAR, wherein said CAR comprises an extracellular antigen-binding domain which binds to a tumor antigen or a tumor microenvironment (TME) antigen; a transmembrane domain; and an intracellular signaling domain comprising the CD40 cytotail. Therapeutic uses of the modified myeloid cell are disclosed.
    Type: Application
    Filed: April 7, 2023
    Publication date: July 10, 2025
    Inventors: Philippe BENAROCH, Jovan NIKOLIC
  • Mutated Glycoprotein of Vesicular Stomatitis Virus
    Publication number: 20250171504
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Application
    Filed: February 14, 2025
    Publication date: May 29, 2025
    Inventors: Aurélie Albertini, Yves Gaudin, Hélène Raux, Laura Belot, Jovan Nikolic
  • Mutated Glycoprotein of Vesicular Stomatitis Virus
    Publication number: 20250171505
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Application
    Filed: February 14, 2025
    Publication date: May 29, 2025
    Inventors: Aurélie Albertini, Yves Gaudin, Héléne Raux, Laura Belot, Jovan Nikolic
  • Mutated glycoprotein of vesicular stomatitis virus
    Patent number: 12297237
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Grant
    Filed: April 8, 2024
    Date of Patent: May 13, 2025
    Assignees: Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay
    Inventors: Aurélie Albertini, Yves Gaudin, Hélène Raux, Laura Belot, Jovan Nikolic
  • Mutated glycoprotein of vesicular stomatitis virus
    Patent number: 12291551
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Grant
    Filed: April 8, 2024
    Date of Patent: May 6, 2025
    Assignees: Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay
    Inventors: Aurélie Albertini, Yves Gaudin, Hélène Raux, Laura Belot, Jovan Nikolic
  • Mutated glycoprotein of vesicular stomatitis virus
    Patent number: 12269848
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Grant
    Filed: April 8, 2024
    Date of Patent: April 8, 2025
    Assignees: Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay
    Inventors: Aurélie Albertini, Yves Gaudin, Hélène Raux, Laura Belot, Jovan Nikolic
  • Mutated glycoprotein of vesicular stomatitis virus
    Patent number: 12264180
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Grant
    Filed: April 8, 2024
    Date of Patent: April 1, 2025
    Assignees: Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay
    Inventors: Aurélie Albertini, Yves Gaudin, Hélène Raux, Laura Belot, Jovan Nikolic
  • Mutated Glycoprotein of Vesicular Stomatitis Virus
    Publication number: 20240327467
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Application
    Filed: April 8, 2024
    Publication date: October 3, 2024
    Inventors: Aurélie Albertini, Yves Gaudin, Hélène Raux, Laura Belot, Jovan Nikolic
  • Mutated Glycoprotein of Vesicular Stomatitis Virus
    Publication number: 20240327466
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Application
    Filed: April 8, 2024
    Publication date: October 3, 2024
    Inventors: Aurélie Albertini, Yves Gaudin, Héléne Raux, Laura Belot, Jovan Nikolic
  • Mutated Glycoprotein of Vesicular Stomatitis Virus
    Publication number: 20240317812
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Application
    Filed: April 8, 2024
    Publication date: September 26, 2024
    Inventors: Aurélie Albertini, Yves Gaudin, Hèlène Raux, Laura Belot, Jovan Nikolic
  • Mutated Glycoprotein of Vesicular Stomatitis Virus
    Publication number: 20240317811
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Application
    Filed: April 8, 2024
    Publication date: September 26, 2024
    Inventors: Aurélie Albertini, Yves Gaudin, Hélène Raux, Laura Belot, Jovan Nikolic
  • Mutated glycoprotein of vesicular stomatitis virus
    Patent number: 12091434
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: September 17, 2024
    Assignees: Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay
    Inventors: Aurélie Albertini, Yves Gaudin, Hélène Raux, Laura Belot, Jovan Nikolic
  • Mutated glycoprotein of vesicular stomatitis virus
    Patent number: 12030915
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Grant
    Filed: September 25, 2023
    Date of Patent: July 9, 2024
    Assignees: Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay
    Inventors: Aurélie Albertini, Yves Gaudin, Hélène Raux, Laura Belot, Jovan Nikolic
  • Mutated Glycoprotein of Vesicular Stomatitis Virus
    Publication number: 20240092839
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Application
    Filed: September 25, 2023
    Publication date: March 21, 2024
    Inventors: Aurélie Albertini, Yves Gaudin, Hélène Raux, Laura Belot, Jovan Nikolic
  • Mutated Glycoprotein of Vesicular Stomatitis Virus
    Publication number: 20200216502
    Abstract: The invention relates to an isolated non-naturally occurring protein comprising the amino acid sequence as set forth in SEQ ID NO: 1, and wherein the amino acid in position 8, 47, 209 and/or 354 is substituted by any amino acid different from the amino acid indicated at that position in said sequence SEQ ID NO: 1.
    Type: Application
    Filed: September 24, 2018
    Publication date: July 9, 2020
    Inventors: Aurélie Albertini, Yves Gaudin, Hélène Raux, Laura Belot, Jovan Nikolic