Patents by Inventor Jovita R. Tauro

Jovita R. Tauro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7943569
    Abstract: The present invention is a composition for providing localized delivery of a therapeutic agent to a subject. The instant composition is a hydrophilic matrix-based prodrug system, wherein a protease substrate peptide acts as extracellular protease degradable spacer binding the therapeutic agent to a hydrophilic matrix. Release of the therapeutic agent is achieved by localized activity of extracellular proteases thereby providing minimal toxicity of the therapeutic agent and maximum release with protease activity. Methods for producing the instant composition and providing localized delivery of a therapeutic agent to a subject are also provided.
    Type: Grant
    Filed: November 16, 2007
    Date of Patent: May 17, 2011
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Richard A. Gemeinhart, Jovita R. Tauro
  • Publication number: 20080131510
    Abstract: The present invention is a composition for providing localized delivery of a therapeutic agent to a subject. The instant composition is a hydrophilic matrix-based prodrug system, wherein a protease substrate peptide acts as extracellular protease degradable spacer binding the therapeutic agent to a hydrophilic matrix. Release of the therapeutic agent is achieved by localized activity of extracellular proteases thereby providing minimal toxicity of the therapeutic agent and maximum release with protease activity. Methods for producing the instant composition and providing localized delivery of a therapeutic agent to a subject are also provided.
    Type: Application
    Filed: November 16, 2007
    Publication date: June 5, 2008
    Inventors: Richard A. Gemeinhart, Jovita R. Tauro