Abstract: Methods and systems for load balancing are described. A network node may replicate content. A lag time may be determined. A data structure may be generated that comprises the lag time.

Abstract: Methods and systems for load balancing are described. A network node may replicate content. A lag time may be determined. A data structure may be generated that comprises the lag time.

Abstract: Methods and systems for load balancing are described. A network node may replicate content. A lag time may be determined. A data structure may be generated that comprises the lag time.

Abstract: Methods and systems for load balancing are described. A network node may replicate content. A lag time may be determined. A data structure may be generated that comprises the lag time.

Abstract: Methods and systems for load balancing are described. A network node may replicate content. A lag time may be determined. A data structure may be generated that comprises the lag time.

Abstract: Aspects of the disclosure relate to routing queries to a network repository and load balancing in a network. For a network repository having a plurality of content storage sites, relative replication latency of data among a pair of content storages sites can be monitored. Data indicative of such replication latency can be distributed among the content storage sites and can be provided, for example, to a network node in a system layer. A traffic and control manager can determine routing pathways for queries based at least in part on the relative replication latency data and performance conditions of network nodes.

Abstract: Aspects of the disclosure relate to routing queries to a network repository and load balancing in a network. For a network repository having a plurality of content storage sites, relative replication latency of data among a pair of content storages sites can be monitored. Data indicative of such replication latency can be distributed among the content storage sites and can be provided, for example, to a network node in a system layer. A traffic and control manager can determine routing pathways for queries based at least in part on the relative replication latency data and performance conditions of network nodes.

Abstract: Aspects of the disclosure relate to routing queries to a network repository and load balancing in a network. For a network repository having a plurality of content storage sites, relative replication latency of data among a pair of content storages sites can be monitored. Data indicative of such replication latency can be distributed among the content storage sites and can be provided, for example, to a network node in a system layer. A traffic and control manager can determine routing pathways for queries based at least in part on the relative replication latency data and performance conditions of network nodes.

Abstract: Aspects of the disclosure relate to routing queries to a network repository and load balancing in a network. For a network repository having a plurality of content storage sites, relative replication latency of data among a pair of content storages sites can be monitored. Data indicative of such replication latency can be distributed among the content storage sites and can be provided, for example, to a network node in a system layer. A traffic and control manager can determine routing pathways for queries based at least in part on the relative replication latency data and performance conditions of network nodes.

Abstract: Aspects of the disclosure relate to routing queries to a network repository and load balancing in a network. For a network repository having a plurality of content storage sites, relative replication latency of data among a pair of content storages sites can be monitored. Data indicative of such replication latency can be distributed among the content storage sites and can be provided, for example, to a network node in a system layer. A traffic and control manager can determine routing pathways for queries based at least in part on the relative replication latency data and performance conditions of network nodes.

Abstract: Crystalline and amorphous polymorphic forms of Atorvastatin magnesium and processes for their preparation are claimed.

Abstract: A novel process of the preparation of amorphous atorvastatin calcium starting from a compound of Formula (II).

Abstract: Crystalline polymorphic form B4 of Atorvastatin magnesium of FIG. 1 and processes for its preparation.

Abstract: In one aspect, the invention provides a process for the production of 5-(4-Fluoro-phenyl)-2-isopropyl-4-phenyl-1-(3,5,7-trihydroxy-heptyl)-1H-pyrrole-3-carboxylic acid phenylamide hemicalcium salt, stereoisomers thereof or polymorphs thereof from a (6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoyl-pyrrolidin-1-yl]-ethyl}-2-phenyl-[1,3,2]dioxaborinan-4-yl)-acetic acid tert-butyl ester.

Abstract: A novel process for the preparation of substantially pure 4-Fluoro-?-[2-methyl-1-oxopropyl]?-oxo-N-?-diphenyl-benzene butane amide.

Abstract: In one aspect, the invention provides a process for the preparation of an amorphous HMG-CoA reductase inhibitor and hydrates thereof of desired particle size, which comprises: dissolving the HMG-CoA reductase inhibitor in a hydroxylic solvent, and removing the solvent by freeze-drying.

Abstract: In one aspect, the invention provides a process for the preparation of a compound of Formula I wherein G is alkyl or aryl, by employing a novel halo-substituted active methylene compound of Formula III wherein X is halogen, and process of preparation thereof.

Abstract: In one aspect, the invention provides a process for the production of 5-(4-Fluoro-phenyl)-2-isopropyl-4-phenyl-1-(3,5,7-trihydroxy-heptyl)-1H-pyrrole-3-carboxylic acid phenylamide hemicalcium salt, stereoisomers thereof or polymorphs thereof from a (6-{2-[2-(4-Fluoro-phenyl)-5-isopropyl-3-phenyl-4-phenylcarbamoyl-pyrrolidin-1-yl]-ethyl}-2-phenyl-[1,3,2]dioxaborinan-4-yl)-acetic acid tert-butyl ester.

Abstract: A novel process for the preparation of compounds of formula I by employing novel halo-substituted active methylene compounds of formula III and process of preparation thereof.

Abstract: The present invention discusses a novel process for the synthesis of [R-(R*,R*)]-2-(4-fluorophenyl)-B,D-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid hemi calcium, atorvastatin. The compound so prepared is useful as inhibitor of the HMG-CoA reductase and may thus be used as hypolipidemic and hypocholesterolemic agent.