Patents by Inventor Joyce DeLeo

Joyce DeLeo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preventing or treating neuropathic pain
    Patent number: 7943588
    Abstract: The present invention is a method for preventing or treating neuropathic pain. Using an agent to decrease the expression or activity of Toll-like receptor 4 (TLR4), behavioral hypersensitivity is attenuated thereby preventing or treating neuropathic pain in a subject in need of such treatment.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: May 17, 2011
    Assignee: Trustees of Dartmouth College
    Inventors: Joyce A. DeLeo, Flobert Y. Tanga
  • Animal model and compounds identified via this model for treatment of chronic pain
    Patent number: 7906514
    Abstract: An animal model for chronic pain, and in particular lower back pain, is provided. Methods of identifying agents and reducing chronic pain with identified agents such as methotrexate are also provided.
    Type: Grant
    Filed: October 28, 1999
    Date of Patent: March 15, 2011
    Assignee: Trustees of Dartmouth College
    Inventors: Joyce A. Deleo, James N. Weinstein
  • Compositions and method for enhancing the therapeutic activity of opiods in treatment of pain
    Patent number: 7763626
    Abstract: Compositions and methods for inhibiting opioid tolerance and opioid withdrawal-induced hyperalgesia are provided.
    Type: Grant
    Filed: May 16, 2005
    Date of Patent: July 27, 2010
    Assignee: Trustees of Dartmouth College
    Inventor: Joyce A. DeLeo
  • Methods for Preventing or Treating Acute and Chronic Pain
    Publication number: 20090227606
    Abstract: The present invention is a method for preventing or treating acute and chronic pain. Using an agent to increase the expression or activity of GLT-1, behavioral hypersensitivity is attenuated thereby preventing or treating acute and chronic pain in a subject in need of such treatment. Methods for identifying agents that prevent or treat acute and chronic pain through modulation of the expression or activity of GLT-1 or the GLT-1 pathway are also provided.
    Type: Application
    Filed: May 21, 2007
    Publication date: September 10, 2009
    Inventor: Joyce A. DeLeo
  • Method of reducing neuropathic pain
    Patent number: 7285270
    Abstract: The present invention relates to methods of treating pain. Monocyte chemoattractant protein-1 (MCP-1) antibodies or binding fragments thereof are used to prevent or reduce behavioral hypersensitivity associated with pain.
    Type: Grant
    Filed: July 31, 2003
    Date of Patent: October 23, 2007
    Assignee: Trustees of Dartmouth College
    Inventor: Joyce A. DeLeo
  • Method for preventing or treating neuropathic pain
    Publication number: 20070244066
    Abstract: The present invention is a method for preventing or treating neuropathic pain. Using an agent to decrease the expression or activity of Toll-like receptor 4 (TLR4), behavioral hypersensitivity is attenuated thereby preventing or treating neuropathic pain in a subject in need of such treatment.
    Type: Application
    Filed: March 27, 2007
    Publication date: October 18, 2007
    Inventors: Joyce DeLeo, Flobert Tanga
  • Compositions and method for enhancing the therapeutic activity of opioids in treatment of pain
    Publication number: 20050282832
    Abstract: Compositions and methods for inhibiting opioid tolerance and opioid withdrawal-induced hyperalgesia are provided.
    Type: Application
    Filed: May 16, 2005
    Publication date: December 22, 2005
    Inventor: Joyce DeLeo
  • Method of preventing or treating pain
    Publication number: 20050158318
    Abstract: The present invention relates to methods of treating pain. Monocyte chemoattractant protein-1 (MCP-1) antibodies or binding fragments thereof are used to prevent or reduce behavioral hypersensitivity associated with pain.
    Type: Application
    Filed: July 31, 2003
    Publication date: July 21, 2005
    Inventor: Joyce DeLeo
  • Compositions and method for decreasing neuropathic pain
    Patent number: 6413976
    Abstract: Compositions containing propentofylline, and methods for treating neuropathic pain with such compositions, are disclosed.
    Type: Grant
    Filed: February 4, 2002
    Date of Patent: July 2, 2002
    Assignee: Trustees of Dartmouth College
    Inventors: Joyce A. DeLeo, Peter Schubert