Patents by Inventor Joyce E. Bischoff

Joyce E. Bischoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD TO INHIBIT ENDOTHELIAL-TO-MESENCHYMAL TRANSITION
    Publication number: 20180311356
    Abstract: Embodiments herein provide for compositions and methods for inhibiting pathological endothelial-to-mesenchymal transition (EndMT), e.g., in endothelial cells and in a mammal. Specially, pathological EndMT can be inhibited by inhibiting CD45, either protein activity or protein expression or both, and optionally also inhibiting TGF-?. Compositions comprising a CD45 inhibitor, a CD45 inhibitor and a TGF-? inhibitor, or a CD45 inhibitor, a TGF-? inhibitor and an anti-fibrosis agent are disclosed.
    Type: Application
    Filed: October 19, 2016
    Publication date: November 1, 2018
    Applicants: THE CHILDREN'S MEDICAL CENTER CORPORATION, THE GENERAL HOSPITAL CORPORATION, THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Inventors: Joyce E. BISCHOFF, Robert A. LEVINE, Elena AIKAWA
  • ENGINEERED VASCULAR ADIPOSE TISSUE
    Publication number: 20130236429
    Abstract: Embodiments of the invention relate to methods, compositions and kits for the in vivo formation of vascularized new adipose tissue in a subject. Combination of endothelial progenitor cells (EPCs) and mesenchymal progenitor cells (MPCs) implanted in vivo in a subject work synergistically to promote the formation vascularized new adipose tissue.
    Type: Application
    Filed: September 22, 2011
    Publication date: September 12, 2013
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Juan M. Melero-Martin, Joyce E. Bischoff
  • METHODS FOR PROMOTING NEOVASCULARIZATION
    Publication number: 20100040584
    Abstract: The success of tissue engineering and therapeutic neovascularization depends on the development of a microvascular network. The present invention provides methods for promoting neovascularization in tissue engineering constructs, tissue repair, and wound healing comprising endothelial and mesenchymal progenitor cells.
    Type: Application
    Filed: December 19, 2007
    Publication date: February 18, 2010
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Juan M. Melero-Martin, Joyce E. Bischoff