Patents by Inventor Joyce H. Keyak

Joyce H. Keyak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11478568
    Abstract: A target tissue can be treated with a radioisotope. Some methods for treating a target tissue with a radioisotope include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material comprises bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: October 25, 2022
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Joyce H. Keyak, Tadashi Kaneko, Harry B. Skinner, Varun Sehgal
  • Publication number: 20190209731
    Abstract: A target tissue can be treated with a radioisotope. Some methods for treating a target tissue with a radioisotope include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material comprises bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.
    Type: Application
    Filed: March 19, 2019
    Publication date: July 11, 2019
    Inventors: Joyce H. Keyak, Tadashi Kaneko, Harry B. Skinner, Varun Sehgal
  • Patent number: 10272173
    Abstract: A target tissue can be treated with a radioisotope. Some methods for treating a target tissue with a radioisotope include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material comprises bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.
    Type: Grant
    Filed: March 20, 2017
    Date of Patent: April 30, 2019
    Assignee: The Regents of the University of California
    Inventors: Joyce H. Keyak, Tadashi Kaneko, Harry B. Skinner, Varun Sehgal
  • Publication number: 20170189576
    Abstract: A target tissue can be treated with a radioisotope. Some methods for treating a target tissue with a radioisotope include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material comprises bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.
    Type: Application
    Filed: March 20, 2017
    Publication date: July 6, 2017
    Inventors: Joyce H. Keyak, Tadashi Kaneko, Harry B. Skinner, Varun Sehgal
  • Patent number: 9597427
    Abstract: A target tissue can be treated with a radioisotope. Some methods for treating a target tissue with a radioisotope include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material comprises bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.
    Type: Grant
    Filed: November 11, 2015
    Date of Patent: March 21, 2017
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Joyce H. Keyak, Tadashi Kaneko, Harry B. Skinner, Varun Sehgal
  • Publication number: 20160058905
    Abstract: A target tissue can be treated with a radioisotope. Some methods for treating a target tissue with a radioisotope include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material comprises bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.
    Type: Application
    Filed: November 11, 2015
    Publication date: March 3, 2016
    Inventors: Joyce H. Keyak, Tadashi Kaneko, Harry B. Skinner, Varun Sehgal
  • Patent number: 9245069
    Abstract: Methods are provided for modeling structural behavior of a bone. For example, the methods can model the structural behavior of a femur, and in particular, a proximal femur, under conditions representing a fall onto the greater trochanter of the proximal femur. In such an embodiment, the method can comprise determining a strength of the femur, by a processor and based on (a) the elastic modulus, (b) the cortical bone yield strength, (c) the stress level ?min, and (d) the post-yield stress-strain slope of the proximal femur.
    Type: Grant
    Filed: February 4, 2013
    Date of Patent: January 26, 2016
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventor: Joyce H. Keyak
  • Patent number: 9198989
    Abstract: Methods are described for treating a target tissue with a radioisotope. Some methods include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material is a bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.
    Type: Grant
    Filed: February 23, 2012
    Date of Patent: December 1, 2015
    Assignee: The Regents of the University of California
    Inventors: Joyce H. Keyak, Tadashi Kaneko, Harry B. Skinner, Varun Sehgal
  • Patent number: 9028499
    Abstract: Methods are described for treating a target tissue with a radioisotope. Some methods include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material is a bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.
    Type: Grant
    Filed: February 23, 2012
    Date of Patent: May 12, 2015
    Assignee: The Regents of the University of California
    Inventors: Joyce H. Keyak, Tadashi Kaneko, Mario Marquez-Miranda
  • Publication number: 20120232325
    Abstract: Methods are described for treating a target tissue with a radioisotope. Some methods include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material is a bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.
    Type: Application
    Filed: February 23, 2012
    Publication date: September 13, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Joyce H. Keyak, Tadashi Kaneko, Harry B. Skinner, Varun Sehgal
  • Publication number: 20120232555
    Abstract: Methods are described for treating a target tissue with a radioisotope. Some methods include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material is a bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.
    Type: Application
    Filed: February 23, 2012
    Publication date: September 13, 2012
    Applicant: The Regents of the University of California
    Inventors: Joyce H. Keyak, Tadashi Kaneko, Mario Marquez-Miranda