Patents by Inventor Joyce Lustbader

Joyce Lustbader has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Long-acting follicle stimulating hormone analogues and uses thereof
    Patent number: 7807620
    Abstract: This invention provides FSH analogues having increased serum half-life relative to FSH. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject.
    Type: Grant
    Filed: July 21, 2006
    Date of Patent: October 5, 2010
    Assignee: The Trustees of Columbia University in the City of New York
    Inventor: Joyce Lustbader
  • Long-acting hormone and growth factor compositions and uses thereof
    Publication number: 20090093411
    Abstract: This invention provides VEGF-FSH compounds having increased serum half-lives relative to either native VEGF or FSH, in which both VEGF and FSH are biologically active. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject, as well as methods for increasing vascularization in a tissue, particularly in ovarian tissue.
    Type: Application
    Filed: September 26, 2008
    Publication date: April 9, 2009
    Inventors: Joyce Lustbader, Leslie Lobel
  • Long-acting hormone and growth factor compositions and uses thereof
    Patent number: 7442684
    Abstract: This invention provides VEGF-FSH compounds having increased serum half-lives relative to either native VEGF or FSH, in which both VEGF and FSH are biologically active. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject, as well as methods for increasing vascularization in a tissue, particularly in ovarian tissue.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: October 28, 2008
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Joyce Lustbader, Leslie Lobel
  • Long-acting follicle stimulating hormone analogues and uses thereof
    Publication number: 20080234186
    Abstract: This invention provides FSH analogues having increased serum half-life relative to FSH. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject.
    Type: Application
    Filed: July 21, 2006
    Publication date: September 25, 2008
    Inventor: Joyce Lustbader
  • Human chorionic gonadotropin antagonists and methods to prevent ovarian hyperstimulation
    Publication number: 20080039372
    Abstract: The present invention is directed to a human chorionic gonadotropin (hCG) antagonist comprising deglycosylated hCG. Methods of recombinantly producing the hCG antagonist in a glycosylation-deficient host cell are also provided. Methods of treating hCG related conditions including ovarian hyperstimulation syndrome, gestational trophoblastic disease, and hCG related tumors by administering an effective amount of the hCG antagonist are also provided herein.
    Type: Application
    Filed: July 20, 2006
    Publication date: February 14, 2008
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventor: Joyce Lustbader
  • Long-acting follicle stimulating hormone analogues and uses thereof
    Patent number: 7202215
    Abstract: This invention provides FSH analogues having increased serum half-life relative to FSH. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: April 10, 2007
    Assignee: The Trustees of Columbia University in the City of New York
    Inventor: Joyce Lustbader
  • Long-acting hormone and growth factor compositions and uses thereof
    Patent number: 7173113
    Abstract: This invention provides VEGF-FSH compounds having increased serum half-lives relative to either native VEGF or FSH, in which both VEGF and FSH are biologically active. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject, as well as methods for increasing vascularization in a tissue, particularly in ovarian tissue.
    Type: Grant
    Filed: April 9, 2002
    Date of Patent: February 6, 2007
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Joyce Lustbader, Leslie Lobel
  • Long-acting follicle stimulating hormone analogues and uses thereof
    Patent number: 7081446
    Abstract: This invention provides FSH analogues having increased serum half-life relative to FSH. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: July 25, 2006
    Assignee: The Trustees of Columbia University in the City of New York
    Inventor: Joyce Lustbader
  • Long-acting hormone and growth factor compositions and uses thereof
    Publication number: 20030216313
    Abstract: This invention provides VEGF-FSH compounds having increased serum half-lives relative to either native VEGF or FSH, in which both VEGF and FSH are biologically active. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject, as well as methods for increasing vascularization in a tissue, particularly in ovarian tissue.
    Type: Application
    Filed: January 31, 2003
    Publication date: November 20, 2003
    Inventors: Joyce Lustbader, Leslie Lobel
  • Long-acting follicle stimulating hormone analogues and uses thereof
    Publication number: 20030211580
    Abstract: This invention provides FSH analogues having increased serum half-life relative to FSH. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject.
    Type: Application
    Filed: January 31, 2003
    Publication date: November 13, 2003
    Inventor: Joyce Lustbader
  • Long-acting hormone and growth factor compositions and uses thereof
    Publication number: 20030144189
    Abstract: This invention provides VEGF-FSH compounds having increased serum half-lives relative to either native VEGF or FSH, in which both VEGF and FSH are biologically active. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject, as well as methods for increasing vascularization in a tissue, particularly in ovarian tissue.
    Type: Application
    Filed: April 9, 2002
    Publication date: July 31, 2003
    Inventors: Joyce Lustbader, Leslie Lobel
  • Long-acting follicle stimulating hormone analogues and uses thereof
    Publication number: 20030143694
    Abstract: This invention provides FSH analogues having increased serum half-life relative to FSH. This invention also provides related compositions and methods for increasing fertility, egg production and spermatogenesis in a subject.
    Type: Application
    Filed: March 27, 2002
    Publication date: July 31, 2003
    Inventor: Joyce Lustbader
  • Expression of properly folded and soluble extracellular domain of a gonadotropin receptor
    Publication number: 20020128190
    Abstract: This invention provides a nucleic acid which encodes a soluble polypeptide which comprises the extracellular domain of a gonadotropin receptor and thioredoxin, wherein the soluble polypeptide is capable of binding to the gonadotropin. This invention also provides the polypeptides encoded by these nucleic acids and methods to produce the polypeptides. This invention also provides methods of preventing or terminating pregnancy, preventing or treating cancer, and decreasing androgen and estrogen production.
    Type: Application
    Filed: March 9, 2001
    Publication date: September 12, 2002
    Inventors: Leslie Lobel, Joyce Lustbader