Abstract: An onboard oxygen system for aircraft includes an oxygen source, a regulator connected to the oxygen source, and an oxygen mask connected to the regulator. The oxygen source is stored in a cavity in a passenger seat armrest. The oxygen mask is stored in a mask storage compartment attached to the armrest. The oxygen mask is deployed for use through an opening in the mask storage compartment.

Abstract: A mounting system (10) for attaching a box (14) in a compartment (12) of an aircraft galley comprises a first guide device set up for engaging with a complementary second guide device designed on the box (14) when the box (14) is inserted into the compartment (12) of the aircraft galley, and further set up for securing the box (14) against movement in the compartment (12) of the aircraft galley in a direction (P) perpendicular to a longitudinal axis (L) of the compartment (12) of the aircraft galley when the device is engaged with the complementary second guide device designed on the box (14). The mounting system (10) further comprises a locking mechanism set up for securing the box (14) against movement in the compartment (12) of the aircraft galley in a direction parallel to the longitudinal axis (L) of the compartment (12) of the aircraft galley.

Abstract: The invention relates to a method for treating disease such as viral infections, tumors, and cancers, comprising administering a TLR7 agonist or TLR7 agonist prodrug according to a cyclical dosing schedule having a dosing period and a resting period. For example, the method encompasses treating disease with: 5-amino-3-(2?-O-acetyl-3?-deoxy-?-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one Tosylate according to a dosing schedule of every-other-day or a dosing schedule of three consecutive days of dosing followed by four consecutive days of not dosing.

Abstract: The invention relates to a method for treating disease such as viral infections, tumors, and cancers, comprising administering a TLR7 agonist or TLR7 agonist prodrug according to a cyclical dosing schedule having a dosing period and a resting period. For example, the method encompasses treating disease with: 5-amino-3-(2?-O-acetyl-3?-deoxy-?-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one Tosylate according to a dosing schedule of every-other-day or a dosing schedule of three consecutive days of dosing followed by four consecutive days of not dosing.

Abstract: A microneedle mold and a method of manufacturing a microneedle mold are provided for use in fabricating microneedles. The method includes providing a microneedle mold base with recesses therein, the recesses corresponding to the microneedles to be fabricated and extending from a first surface of the microneedle mold base; and forming side-port forming holes in the microneedle mold base, the side-port forming holes extend in side surfaces of the recesses within the microneedle mold base at side-port forming positions of the recesses.

Abstract: A sliding door system includes at least one sliding door having an upper and lower sliding-door mount, as well as an upper and lower guide rail for displaceably receiving the upper and lower sliding-door mount, respectively. The guide rails extend parallel to each other and each have a clear inner width that is at least twice as large as the thickness of the sliding door. The upper and lower sliding-door mounts are each at most half as wide as the clear inner width of each guide rail, allowing moving the sliding door into recessed and lifted-out positions, each constituting a stable state. By overcoming a resistance force, the sliding door can be moved between stable states. The sliding door system is lightweight and robust, and enables sliding doors to be displaced freely without a particular sliding door being assigned in a fixed manner to a particular opening to be covered.

Abstract: The invention relates to a transport cart (10) for loading an aircraft galley, comprising a base element (12) and a plurality of wheels (14) attached to the base element (12). Two frame elements (20, 24) are connected to the base element (12) and disposed at a distance from each other. A first guide device (28, 28?, 28?) is set up for engaging a complementary second guide device formed on a box that is receivable in the aircraft galley to be loaded and for transporting on the transport cart (10). The first guide device (28, 28?, 28?) is further set up for securing the box against displacement on the transport cart (10) in a direction perpendicular to a longitudinal axis (L) of the transport cart (10) when engaged with the complementary second guide device formed on the box. The transport cart (10) finally comprises a locking mechanism (40, 40?) which is set up for securing the box against displacement on the transport cart in a direction parallel to the longitudinal axis (L) of the transport cart (10).

Abstract: Disclosed herein is a folding transport cart which in a parking configuration has a minimum extension and in an operative configuration has a maximum extension in a transverse direction. A folding transport cart can comprise: two side parts which extend substantially perpendicular to the transverse direction of the transport cart, and a folding base part which comprises two flat base segments which are each connected on one base side axis for articulated movement to one side part and are connected on a common base central axis for articulated movement to one another. In order to ensure reliable folding and unfolding the transport cart can comprise a base locking mechanism for locking the folding base part in the operative configuration and a cover part which is connected for articulated movement to one of the side parts.

Abstract: A galley including a galley body on a cabin floor for accommodating storage boxes, appliances and at least one service cart; storage boxes for storing goods, and a service cart. The galley body has a plurality of vertical levels that are substantially equidistant from each other, each of the vertical levels divided into a plurality of laterally adjacent compartments whose horizontal and vertical dimensions are equal to an integer multiple of the respective dimensions of a single one of the storage boxes. A transfer table is provided in front of the galley body for access to the compartments. A method includes catering for passengers on an aircraft.

Abstract: A sliding door system includes at least one sliding door having an upper and lower sliding-door mount, as well as an upper and lower guide rail for displaceably receiving the upper and lower sliding-door mount, respectively. The guide rails extend parallel to each other and each have a clear inner width that is at least twice as large as the thickness of the sliding door. The upper and lower sliding-door mounts are each at most half as wide as the clear inner width of each guide rail, allowing moving the sliding door into recessed and lifted-out positions, each constituting a stable state. By overcoming a resistance force, the sliding door can be moved between stable states. The sliding door system is lightweight and robust, and enables sliding doors to be displaced freely without a particular sliding door being assigned in a fixed manner to a particular opening to be covered.

Abstract: A fastening arrangement for fastening a storage container in a compartment of an aircraft galley comprises a latching mechanism including a latch and a first biasing mechanism, the first biasing mechanism being adapted to bias the latch into a latched position in a first operational state of the latching mechanism, such that the latch is adapted to interact with the storage container upon insertion of the storage container into the compartment of the aircraft galley so as to be moved from its latched position into an unlatched position against the biasing force applied to the latch by the first biasing mechanism, and such that the latch is adapted to be moved back into its latched position by the biasing force applied to the latch by the first biasing mechanism when the storage container has reached a predefined position in the compartment of the aircraft galley.

Abstract: A mounting system (10) for attaching a box (14) in a compartment (12) of an aircraft galley comprises a first guide device set up for engaging with a complementary second guide device designed on the box (14) when the box (14) is inserted into the compartment (12) of the aircraft galley, and further set up for securing the box (14) against movement in the compartment (12) of the aircraft galley in a direction (P) perpendicular to a longitudinal axis (L) of the compartment (12) of the aircraft galley when the device is engaged with the complementary second guide device designed on the box (14). The mounting system (10) further comprises a locking mechanism set up for securing the box (14) against movement in the compartment (12) of the aircraft galley in a direction parallel to the longitudinal axis (L) of the compartment (12) of the aircraft galley.

Abstract: The invention relates to a transport cart (10) for loading an aircraft galley, comprising a base element (12) and a plurality of wheels (14) attached to the base element (12). Two frame elements (20, 24) are connected to the base element (12) and disposed at a distance from each other. A first guide device (28, 28?, 28?) is set up for engaging a complementary second guide device formed on a box that is receivable in the aircraft galley to be loaded and for transporting on the transport cart (10). The first guide device (28, 28?, 28?) is further set up for securing the box against displacement on the transport cart (10) in a direction perpendicular to a longitudinal axis (L) of the transport cart (10) when engaged with the complementary second guide device formed on the box. The transport cart (10) finally comprises a locking mechanism (40, 40?) which is set up for securing the box against displacement on the transport cart in a direction parallel to the longitudinal axis (L) of the transport cart (10).

Abstract: The invention relates to a method for treating disease such as viral infections, tumors, and cancers, comprising administering a TLR7 agonist or TLR7 agonist prodrug according to a cyclical dosing schedule having a dosing period and a resting period. For example, the method encompasses treating disease with: Formula (I) 5-amino-3-(2?-Q-acetyl-3?-deoxy-?-D-ri-bofuranosyl)-3H-thia-zolo[4,5-d]pyrimidin-2-one Tosylate according to a dosing schedule of every-other-day or a dosing schedule of three consecutive days of dosing followed by four consecutive days of not dosing.

Abstract: The invention relates to a folding transport cart which in a parking configuration has a minimum extension and in a operative configuration has a maximum extension in a transverse direction which comprises: two side parts which extend substantially perpendicular to the transverse direction of the transport cart, and a folding base part which comprises two flat base segments which are each connected on one base side axis for articulated movement to one side part and are connected on a common base central axis for articulated movement to one another so that they can be folded inwards into the transport cart.

Abstract: Side-ported microneedles are produced from a suitably shaped microneedle mould (40). A microneedle mould base (32) is made with a number of microneedle mould recesses (30) in it. One surface of the microneedle mould base (32) is coated with a seed layer (34). The microneedle mould base (32) contains two microneedle mould sheets (24, 26), which are separated to gain access to an internal surface of one of the microneedle mould sheets (24, 26). Side-port forming channels (38) are formed on one of the internal surfaces, intersecting with the recesses (30) within the relevant microneedle mould sheet (24). The two microneedle mould sheets (24, 26) are placed back together and joined together as a unitary microneedle mould (40). The microneedles are formed in the recesses (30) by depositing a microneedle layer (44) therein and on the surface with the seed layer (34).

Abstract: A galley including a galley body on a cabin floor for accommodating storage boxes, appliances and at least one service cart; storage boxes for storing goods, and a service cart. The galley body has a plurality of vertical levels that are substantially equidistant from each other, each of the vertical levels divided into a plurality of laterally adjacent compartments whose horizontal and vertical dimensions are equal to an integer multiple of the respective dimensions of a single one of the storage boxes. A transfer table is provided in front of the galley body for access to the compartments. A method includes catering for passengers on an aircraft.