Patents by Inventor Jozo Delic

Jozo Delic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of nanodiamonds for generating free radicals for therapeutic purposes under radiation
    Patent number: 10391172
    Abstract: The present invention relates to the use of nanodiamonds as drugs generating free radicals, in particular for treating tumors. The invention is based on generating free radicals on the surface of the nanodiamonds when they are exposed to radiation, for example ionizing radiation. In order to increase the effectiveness of the nanodiamonds, the nanodiamonds can be complexed with a radiosensitizing agent, such as a chemical molecule or an interfering RNA targeting a repairing gene.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: August 27, 2019
    Assignee: Commissariat a L'Energie Atomique et aux Energies Alternatives
    Inventors: Tristan Petit, Jean-Charles Arnault, Hugues Girard, Romain Grall, Sylvie Chevillard, Jozo Delic
  • METHOD FOR EVALUATING, VIA BIODOSIMETRY, THE IRRADIATION DOSE RECEIVED BY A PERSON SUBJECTED TO IONIZING RADIATION
    Publication number: 20160202234
    Abstract: The invention relates to a method for evaluating, via biodosimetry, the irradiation dose received by a person subjected to ionizing radiation. Said method comprises: a) sampling, in at least one area of the body of the person, the follicles or bulbs of head and/or body hair of the person; b) extracting proteins from cells of said sampled hair bulbs or follicles, wherein said proteins, including proteins from the ATM system, are subjected to phosphorylation and/or acetylation induced by ionizing radiation; and c) analyzing at least two types of extracted proteins and interpreting the analysis results in order to determine the irradiation dose in the or each sampling area.
    Type: Application
    Filed: May 15, 2014
    Publication date: July 14, 2016
    Applicant: ACUBENS
    Inventors: Ivana JUKIC, Amélie SCHELLENBERG, Jozo DELIC, Arnaud TUPINIER, Vincent PAGET, Yohann FEDOR, Luc MORAT, Nicolas UGOLIN, Caroline FLACK, Sylvie CHEVILLARD, Emilie LEFEVRE
  • USE OF NANODIAMONDS FOR GENERATING FREE RADICALS FOR THERAPEUTIC PURPOSES UNDER RADIATION
    Publication number: 20150182624
    Abstract: The present invention relates to the use of nanodiamonds as drugs generating free radicals, in particular for treating tumours. The invention is based on generating free radicals on the surface of the nanodiamonds when they are exposed to radiation, for example ionising radiation. In order to increase the effectiveness of the nanodiamonds, the nanodiamonds can be complexed with a radiosensitising agent, such as a chemical molecule or an interfering RNA targeting a repairing gene.
    Type: Application
    Filed: July 12, 2013
    Publication date: July 2, 2015
    Inventors: Tristan Petit, Jean-Charles Arnault, Hugues Girard, Romain Grall, Sylvie Chevillard, Jozo Delic