Abstract: New Formula (I) compounds are disclosed having NR2B selective NMDA receptor antagonist activity 1

Abstract: Controlled release pharmaceutical preparations are prepared by homogenizing an organic or inorganic pharmaceutical active substance such as an opium alkaloid or its salts, an opium antagonist or its salts, an aliphatic or aromatic amine derivative or its salts, a phenolate type medicament, or Zn, Fe, Mg, K, Na salts, a fatty acid or its salt necessary to achieve a continuous phase transfer and an ethylene vinyl acetate copolymer and formulating the resulting homogeneous mixture bya) direct compressing orb) admixing with a solvent orc) using a second, auxiliary polymer.The preparations are suitable for oral or rectal administration or for tissue implantation.

Abstract: The invention relates to a process for the preparation and use of antidote-carrying maize plant parts which are useful for lowering the cultivated plant-damaging effect of thiolcarbamates and chloroacetanilides, which comprises treating native or artificially genmanipulated macroorganisms living in the soil or on the soil surface by the thiolcarbamate and chloroacetanilides compounds and using the living organisms thus made antidote-carrying for the treatment of field soils in a fresh state or after preservation by lyophilization or by application onto a carrier in their original state or after working up them by crushing, pulverisation, extraction or drying, before or simultaneously with or after the treatment with the herbicides, in any time until the germination of the cultivated plant, whereby the selectivity of thiolcarbamates of the formula (I) and chloroacetanilides against cultivated plants, preferably against the maize is increased.

Abstract: The invention relates to novel 9.alpha.-hydroxy-3-oxo-4,24(25)-stigmastadien-26-oic acid derivatives of the formula (I), ##STR1## wherein M stands for hydrogen, C.sub.1-4 alkyl or a pharmaceutically accteptable cation to a process for repairing these compounds and to compositions containing said compounds which exert an anti-hypercholesteremic effect.

Abstract: The invention relates to a multilayer pharmaceutical formulation containing layers with various active ingredient content, a water-impermeable layer applied thereon and an adhesive layer ensuring the fixation to the body surface of the pharmaceutical formulation, which comprises: a silicone rubber layer directly contacting with the skin surface and ensuring the zero order kinetics of the dissolution of the active ingredient; as well as a multilaminated silicone rubber matrix comprising one or more layers(s) with various active ingredient content.

Abstract: The invention relates to synergistic fungicidal and acaricidal compositions containing two or three active ingredients in a ratio of 10:1-1:10 and 20:1:1-1:10:10, selected from the group of N-alkyl(ene)-N-(0,0-disubstituted-thiophosphoryl)-N', N'-substituted glycine amide derivatives, Triforine, Carbendazim, copper-oxyquinolate, cycloheximide, Mancozeb, benzimidazole derivatives, phenyl amide derivatives F-849, Folpet, Captofol, Iprodione or S-39475.

Abstract: The present invention relates to novel compounds of the formula (I) ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and stand for alkyl having 1 to 4 carbon atoms optionally substituted by one or more halogen atoms, alkenyl having 2 to 6 carbon atoms, cycloalkyl having 3 to 6 carbon atoms, phenyl or lower alkoxy-alkyl group,R.sub.3 stands for alkyl having 1 to 6 carbon atoms or alkenyl having 2 to 6 carbont atoms,R.sub.4 and R.sub.5 are the same or different and represent hydrogen, alkyl having 1 to 6 carbon atoms, alkenyl having 2 to 6 carbon atoms, cycloalkyl having 3 to 6 carbon atoms, phenyl, benzyl, phenyl substituted by one or more alkyl having 1 to 3 carbon atoms and/or by one or more halogen atoms, lower alkoxy-alkyl, a group of the formula --(CH.sub.2).sub.n --R.sub.6, wherein n is an integer between 0 to 3 and R.sub.

Abstract: The present invention relates to novel compounds of the formula (I) ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and stand for alkyl having 1 to 4 carbon atoms optionally substituted by one or more halogen atoms, alkenyl having 2 to 6 carbon atoms, cycloalkyl having 3 to 6 carbon atoms, phenyl or lower alkoxy-alkyl group,R.sub.3 stands for alkyl having 1 to 6 carbon atoms or alkenyl having 2 to 6 carbon atoms,R.sub.4 and R.sub.5 are the same or different and represent hydrogen, alkyl having 1 to 6 carbon atoms, alkenyl having 2 to 6 carbon atoms, cycloalkyl having 3 to 6 carbon atoms, phenyl, benzyl, phenyl substituted by one or more alkyl having 1 to 3 carbon atoms and/or by one or more halogen atoms, lower alkoxy-alkyl, a group of the formula --(CH.sub.2).sub.n --R.sub.6, wherein n is an integer between 0 to 3 and R.sub.

Abstract: The invention relates to compositions useful for prolonging the action and increasing the selectivity of herbicide compositions containing .alpha.-chloroacetamide derivatives as active ingredient as well as to highly selective herbicide compositions containing .alpha.-chloroacetamide derivatives as active ingredients and optionally an antidote wherein an animal derivative of the general formula (III) is used for achieving the prolonged action and increased selectivity. In the formula (III) ##STR1## R.sub.5, R.sub.6, R.sub.7 and R.sub.8 stand independently for hydrogen, a C.sub.1-6 alkyl, C.sub.3-7 cycloalkyl or C.sub.2-5 alkenyl group optionally substituted by a C.sub.1-4 alkyl group; andR.sub.9 stands for hydrogen or a C.sub.1-4 alkyl group optionally substituted by halogen, or a phenyl group.

Abstract: The invention relates to a herbicide composition comprising as herbicidally active ingredient an urea derivative and/or a thiolcargamate derivative and/or a chloroacetanilide derivative together with a nitrile derivative of the general formula (I), ##STR1## wherein R.sub.1 and R.sub.2 which are the same or different, stand for hydroger, halogen or a methyl, ethyl, allyl, vinyl, phenyl or benzyl group; orR.sub.1 and R.sub.2 together may stand for a benzylidene group; andR.sub.3 means chlorine or a methyl, phenyl, chlorophenyl, alkoxyphenyl, chlorophenylamino, anilino, anilinomethylene, N-alkylanilinomethylene, N,N-dialkylanilinomethylene, alkoxyanilinomethylene, benzylaminomethylene, cyclohexylaminomethylene, N-alkyl-cyclohexylaminomethylene, hexamethyleniminomethylene, phthalimidomethylene, nitrophthalimidomethylene, morpholinomethylene, piperidinomethylene, C.sub.1-3 alkylaminomethylene, allylaminomethylene or di(C.sub.

Abstract: The invention relates to a synergistic fungicidal composition containing more active ingredients comprising 2,3-dihydroxy-6-methyl-5-phenylcarbamoyl-1,4-oxathiine or 2.3-dihydro-6-methyl-5-phenylcarbamoyl-1,4-oxathiine-4,4-dioxide and the zinc and manganese complexes of (8-oxyquinolinate)-(dimethyl dithiocarbamate) as active ingredients, optionally solid and/or liquid carriers and other excipients. The compositions is of value especially in the treatment of infections caused by ustilaginales and yellow rust on cereals.

Abstract: The invention relates to a capacitive measuring element intended for continuous measurements of conductance in streaming solutions. The essence of the measuring element is that in the measuring space the surfaces limiting it are covered by an electrically insulating material. A method for obtaining the dimensions of the measuring element has also been proposed. According to the measuring element of the invention the measurements of concentration from very low values with high accuracy and low noise level are possible. The life duration and the reliability of the measuring element are high, and it shows a high resistivity against corrosive media to be measured.

Abstract: The present invention relates to novel N- and optionally N'-substituted (N-dichloroacetyl)glycine amides of the formula I with antidote action, to antidote compositions containing such compounds, to selective herbicide compositions containing these antidotes together with herbicidally active compounds and to a method for treating cultivated plants with said compositions.

Abstract: The invention relates to new compositions which contain 0.5 to 90% by weight of a phthalazine derivative having the general formula (I), ##STR1## wherein R.sub.1 stands for hydrogen, halogen, a straight-chained or branched C.sub.1-4 alkyl group having optionally a chlorine or hydroxy substituent, a C.sub.2-4 alkenyl group, or an optionally alkyl-substituted amino, sulfhydryl or hydroxy group, andB.sub.1 and B.sub.2, which may be identical or different, have no meaning or stand for guanidine and/or hydrazine base,and/or an imidazole derivative of the general formula (II), ##STR2## wherein n is equal to zero or 4,R.sub.2 stands for hydrogen, a straight-chained or branched C.sub.1-5 alkyl group having optionally a chlorine or hydroxy substituent, or a C.sub.2-5 alkenyl group,X stands for an organic or inorganic anion, andin the compounds of the general formula (II) wherein n is equal to 4 R.sub.

Abstract: The invention relates to a synergistic fungicidal composition containing more active ingredients comprising benzimidazole-2-ylmethylcarbamate and the zinc and manganese complexes of (8-oxyquinolinate)-(dimethyl dithiocarbamate) as active ingredients, optionally solid and/or liquid carrier(s) and other excipient(s).The composition is of value especially in the treatment of infections caused by ustilaginales, powdery mildew and fusarium species on cereals.

Abstract: The invention relates to a herbicide composition as well as to the preparation of carboxylic-acid-amido-thiol-carbamate derivatives forming the active agent of the composition. The carboxylic acid-amido-thiolcarbamate derivatives are illustrated by general formula (I) ##STR1## wherein R.sub.1 and R.sub.2 can be identical or different and can stand for hydrogen, a C.sub.1-10 straight or branched alkyl group, a C.sub.2-10 straight or branched alkenyl group, a C.sub.5-6 cycloalkyl or phenyl group, a phenyl radical substituted by a C.sub.1-3 alkyl group, a C.sub.1-3 dialkyl group or halogen, but R.sub.1 and R.sub.2 can form together a hexamethylene group, too;R.sub.2 can stand for a C.sub.1-5 straight or branched alkyl radical;R.sub.4 can represent a C.sub.1-10 straight or branched alkyl group, a C.sub.2-10 straight or branched alkenyl group, furthermore a phenyl or benzyl radical.

Abstract: A silicon rubber embolization agent used in general as well as cerebral vascular surgery having a component A which is composed of: a linear, low viscosity polysiloxane selected from the group consisting of dialkyl, alkylaryl, alkenylalkyl, and diarylpolysiloxanes having reactive functional groups selected from the group consisting of hydroxyl, acyloxyl, alkoxyl and amino; a low viscosity cyclic dialkylpolysiloxane having the formula [R.sub.2 SiO].sub.4, wherein R is alkyl; a pharmaceutically acceptable iodo-containing organosilicium; or a non-metallic, organic X-ray contrast material, and a component B which is a therapeutically acceptable cross-linking catalyst.

Abstract: The invention relates to a plant growth regulating composition which contains as active agent a compound of general formula (I) ##STR1## wherein R.sub.1 and R.sub.2 can be identical or different and can stand for hydrogen, a C.sub.1-4 straight or branched alkyl group, cyclohexyl, phenyl, chlorophenyl, alkylphenyl, benzyl or alkylbenzyl group, or R.sub.1 and R.sub.2 can together with the N atoms form a heterocyclic ring.The growing of plants can be stimulated and the green weight can be increased to a significant degree by the treatment carried out with the composition of the invention.

Abstract: The invention relates to new compositions for increasing the cold resistance of cultivated plants. These compositions contain as active ingredient at least one compound of the general formula (I), ##STR1## wherein n is an integer of 2 to 5 and R.sub.1, R.sub.2 and R.sub.3 each stand for hydrogen or C.sub.1-5 alkyl, or an acid addition salt thereof in an amount of 0.01 to 70% by weight, together with a conventional diluent and/or additive.The plants treated with the compositions according to the invention are more resistant to cold and frost.

Abstract: A therapeutic set or kit containing a silicon rubber mixture for surgical embolization composed of(a) a linear, low viscosity polysiloxane selected from the group consisting of dialkyl, alkylaryl, alkenylalkyl, and diaryl polysiloxanes having reactive functional groups selected from the group consisting of hydroxy, acyloxy, alkoxy and amino;(b) a cyclic dialkyl polysiloxane having the formula [R.sub.2 SiO].sub.4, wherein R is alkyl; anda pharmaceutically acceptable iodo-containing organosilicium X-ray contrast material or non-metallic organic X-ray contrast material. The mixture can be used in cerebrovascular surgery and general surgery for surgical embolization with the aid of a catheter.