Abstract: Proposed is radish sprout-derived PDRN that strengthens a skin basement membrane and barrier, protects the skin from reactive oxygen species (ROS), and enhances skin defense by further activating the NRF-2 pathway under oxidative stress. Accordingly, the composition containing the radish sprout-derived PDRN can be usefully used to maintain a healthy and firm skin environment, and can be widely applied as a cosmetic for antioxidant and skin barrier protection purposes.

Abstract: The present invention relates to a method for preparing a mutant strain having high producibility of phytoene and a mutant strain prepared thereby. More particularly, a Deinococcus radiodurans mutant strain, prepared by the method of the present invention, having high producibility of phytoene, does not retain an artificial antibiotic-resistant gene, although constructed by introducing a metabolism engineering method, and has high producibility of phytoene. Thus, the mutant strain prepared according to the method can find useful applications in the mass production of phytoene.

Abstract: The present invention relates to a method for preparing a mutant strain having high producibility of phytoene and a mutant strain prepared thereby. More particularly, a Deinococcus radiodurans mutant strain, prepared by the method of the present invention, having high producibility of phytoene, does not retain an artificial antibiotic-resistant gene, although constructed by introducing a metabolism engineering method, and has high producibility of phytoene. Thus, the mutant strain prepared according to the method can find useful applications in the mass production of phytoene.