Abstract: A spatial positioning method is provided. The method includes steps of: dividing an activity space into a plurality of activity regions; selecting a plurality of positions in the activity space or within a distance range of the activity space as a plurality of base station candidate positions; predicting connection states between the plurality of base stations that are disposed respectively at the plurality of station candidate positions and a mobile robot moving to each of the plurality of activity regions; selecting some of the base station candidate positions as a plurality of base station positions according to the connection states; disposing the plurality of base stations respectively at the plurality of base station positions; and wirelessly connecting the mobile robot respectively moving to the plurality of activity regions to some of the plurality of base stations to position the mobile robot.