Abstract: The present invention is directed to a cytokine fusion protein comprising an immunocyte targeting domain and a cytokine function domain capable of specifically inducing the proliferation and/or activation of immunocytes. Specifically, the present invention is directed to a fusion protein that specifically delivers cytokines (e.g., IL-2 or IL-15) to exhausted immunocytes (e.g., exhausted T cells) in tumors to induce and increase the activation of the immunocytes. The fusion protein of the present invention can deliver a cytokine, which promotes the proliferation or activation of the immunocyte, selectively to the effector T cells, etc. in the tumor microenvironment, thereby inducing strong immune enhancement and anti-cancer response in tumors and significantly reducing systemic toxicity or side effects of cytokines through the unique structure of the cytokine function domain.

Abstract: A battery diagnosing apparatus, a battery pack, an electric vehicle and a battery diagnosing method are provided. The battery diagnosing apparatus is provided for a battery array including first to mth batteries (m is a natural number of 3 or more) connected in series. The battery diagnosing apparatus includes voltage sensors configured to detect voltage of each of the first to mth batteries, and a controller configured to generate first to mth voltage profiles representing a voltage change history of each of the first to mth batteries during charging or discharging of the battery array. The controller diagnoses the battery array by comparing each of first to (m?1)th comparison voltage profiles with a criterion voltage profile. The criterion voltage profile is one of the first to mth voltage profiles, and the first to (m?1)th comparison voltage profiles are remaining (m?1) voltage profiles other than the criterion voltage profile.

Abstract: A battery diagnosing apparatus includes a battery sensing unit configured to generate a voltage detection signal indicating voltage of a target battery and a current detection signal indicating current of the target battery. The battery diagnosing apparatus also includes a battery diagnosing unit configured to generate a measurement voltage profile representing the correspondence between an accumulated capacity and the voltage of the target battery in a period of interest by monitoring the voltage and current of the target battery while the target battery is being charged or discharged and diagnose abnormality of the target battery by comparing the measurement voltage profile with a criterion voltage profile.

Abstract: The resin composition according to an exemplary embodiment of the present application comprises: an epoxy-based resin; a curing agent comprising a cyanate ester-based resin and a phenolic resin; inorganic particles comprising silica particles; and a curing accelerator, the weight ratio of the cyanate ester-based resin:the phenolic resin is 95:5 to 40:60, and the curing accelerator comprises both an imidazole-based compound and a metal-based compound.

Abstract: The locking device includes a cam member rotatable about a second axis parallel to a first axis and a rotator for transmitting rotational force of an armrest to the cam member in a contact manner to control rotation of the cam member. When the armrest is rotated, the rotator is rotated about the first axis, and a locking tooth of the rotator is moved so as to pass through a locking position. The cam member is rotated in accordance with control operation of rotation of the rotator, and a locking recess in the cam member is moved so as to pass through the locking position. When the armrest is rotated to assume a locking posture, the locking tooth and the locking recess are moved to the locking position, and the locking tooth is inserted into the locking recess.

Abstract: The armrest assembly includes a locking device for restricting an armrest when the armrest assumes a locking posture, thereby limiting rotation of the armrest. The locking device includes a lock shaft fixed on the center of rotation of the armrest and a lock provided at the armrest SO as to be movable in a locking direction approaching the lock shaft and an unlocking direction away from the lock shaft in accordance with operation of the knob. A locking section including a recess into which a lock tooth is inserted when the armrest is in the locking posture and an unlocking section extending from the locking section are formed along the periphery of the lock shaft, and the unlocking section includes an unlocking surface that contacts a tooth end to maintain the lock in the state of being moved in the unlocking direction.

Abstract: An optical communication device includes a laser, a transmitter (Tx), a receiver (Rx) and a device controller. The laser is configured to generate an optical carrier. The transmitter is configured to generate an optical Tx signal using the optical carrier and to transmit the optical Tx signal to a peer optical communication device. The receiver is configured to receive an optical Rx signal from the peer optical communication device, and to down-convert the optical Rx signal using the optical carrier. The device controller is configured to adjust a frequency of the laser to reduce a Carrier Frequency Offset (CFO) between the received optical Rx signal and the optical carrier generated by the laser, including conditionally applying to a frequency of the laser a series of frequency hops in accordance with a defined dithering sequence.

Abstract: A storage device includes a nonvolatile memory device; and a controller configured to, sequentially receive first read commands and a first write command, the first write command being associated with first write data, slice the first write command to generate a plurality of sub-commands, slice the first write data to generate a plurality of sub-data elements, and alternately transmit, to the nonvolatile memory device, at least one read command of the first read commands, and one sub-command of the plurality of sub-commands and one sub-data element of the plurality of sub-data elements.

Abstract: The present invention relates to a battery cell including an electrolyte ion concentration measurement unit and a method for measuring an electrolyte concentration using same. The battery cell according to the present invention comprises a measurement unit in which a first electrode plate, an insulation film, and a second electrode plate are sequentially stacked on one another, wherein the measurement unit is inserted between a separator of the battery cell and an electrode thereof, and thus can directly measure an electrolyte concentration between the separator and the electrode. Therefore, the battery cell can be simply manufactured and has excellent stability.

Abstract: The present invention relates to a method and system for evaluating insulation and lithium ion conductivity characteristics of a separator for an electrochemical device, in which insulation and lithium ion conductivity characteristics are evaluated while a separator-containing measurement object to be tested and an electrochemical device are made to face each other, and thus, the insulation and lithium ion conductivity characteristics of the separator can be evaluated by reflecting temperature and pressure changes and the like according to the actual operation state of the electrochemical device.

Abstract: Disclosed are oxadiazole compounds and pharmaceutically acceptable salts thereof. The compounds and pharmaceutically acceptable salts thereof are specifically suitable for the treatment of neurological diseases such as epilepsy.

Abstract: A super-steep switching device is provided. The super-steep switching device may include a substrate, a semiconductor channel on the substrate, a source electrode and a drain electrode, which are disposed on the semiconductor channel and spaced apart from each other, a gate electrode overlapping a portion of the semiconductor channel and not overlapping a remaining portion of the semiconductor channel, and an insulating layer disposed between the gate electrode and the semiconductor channel and covering an entire surface of the semiconductor channel.

Abstract: Disclosed is a battery diagnosing technology capable of effectively diagnosing a state of a secondary battery using a charge and discharge signal extracted from the secondary battery.

Abstract: Disclosed are oxadiazole compounds and pharmaceutically acceptable salts thereof. The compounds and pharmaceutically acceptable salts thereof are specifically suitable for the treatment of neurological diseases such as epilepsy.

Abstract: A secondary battery diagnosing technology capable of effectively diagnosing a state of a secondary battery using a charge and discharge signal of the secondary battery, including a memory unit configured to store a positive electrode reference profile and a negative electrode reference profile for charge or discharge of a reference battery, a voltage measuring unit configured to measure a voltage of a target battery during a charge or discharge process, and a processor configured to generate a charge and discharge measurement profile based on the voltage, compare a simulation profile obtained from the positive electrode reference profile and the negative electrode reference profile with the generated charge and discharge measurement profile, and determine a positive electrode adjustment profile and a negative electrode adjustment profile so that an error between the simulation profile and the charge and discharge measurement profile is within a predetermined level.

Abstract: The present invention relates to a use for the purpose of preventing, alleviating, or treating status epilepticus by administering a medicament or pharmaceutical composition comprising a carbamate compound of chemical formula.

Abstract: The present invention relates to a method for manufacturing a secondary battery and a secondary battery. The method for manufacturing the secondary battery comprises an accommodation step of accommodating an electrode assembly in an accommodation part of a battery case, a vent membrane mounting step of mounting a vent membrane on a discharge hole, which passes between the inside and outside of the battery case, in the battery case, and a case sealing step of sealing the battery case, wherein the vent membrane allows only a gas to pass through the discharge hole of the battery case, but blocks a liquid.

Abstract: The present disclosure provides a compound of Chemical Formula (1) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same: wherein X, Z, R1 and R2 are as defined in the specification. The compound of Chemical Formula (1) or pharmaceutically acceptable salt thereof acts as a positive allosteric modulator of metabotropic glutamate receptor subtype 5 (mGluR5), thereby being useful in the prevention or treatment of disorder mediated by glutamate dysfunction and mGluR5.

Abstract: A battery diagnosing technology capable of effectively diagnosing a state of a secondary battery using a charge and discharge signal extracted from the secondary battery, including memory to store a positive electrode reference profile and a negative electrode reference profile for charge or discharge of a reference battery, a voltage sensor to measure a voltage of a target battery during a charge or discharge process, and a processor to generate a plurality of charge and discharge measurement profiles based on voltages measured at a plurality of different time points, compare each of the generated charge and discharge measurement profiles with a simulation profile obtained from the positive and negative electrode reference profiles, and determine positive and negative electrode adjustment profiles for each of the generated charge and discharge measurement profiles so that an error between each charge and discharge measurement profile and the simulation profile is within a predetermined level.