Abstract: A transcranial direct current stimulation (tDCS) apparatus includes a stimulation unit, a control unit, and an input/output (I/O) unit. The stimulation unit includes a power-supply unit to supply power for electrical stimulation corresponding to a control signal received from the control unit, and a plurality of stimulation electrodes, each of which has a hydrogel patch, to provide electrical stimulation to a living body upon receiving the power from the power-supply unit. The control unit is configured to control an on/off function of the power-supply unit such that the power-supply unit is turned on or off according to the amount of power applied to the stimulation electrodes and a time period during which the power is supplied or not supplied.

Abstract: Provided is an endless rolling apparatus and method, which have improved cooling conditions for producing advanced high strength steel. The endless rolling apparatus includes: a continuous casting machine for casting a slab; and a cooling bed having at least one piece of water-cooling equipment and at least one rolling mill continuously connected to the continuous casting machine, wherein, in the cooling bed, an initial position (S) at which the water-cooling equipment is provided so as to manufacture advanced high strength steel through at least one water-cooling is defined by mathematical formula 1. Here, H is the thickness (mm) of a slab, V is the casting speed (m/sec) of the slab, h is the product thickness (mm), and t is the target arrival time (sec) until entry into the cooling bed.

Abstract: The present invention relates to a commodity's market sustainability measurement system and method for measuring a sustainability of a commodity in a market, and more particularly, to a commodity's market sustainability measurement system and method for establishing a sustainable strategy more efficiently and accurately in the fashion market and measuring a market sustainability of the commodity more precisely than measuring the market sustainability of the commodity in the three sectors of economy, environment, and society in the past by measuring market sustainability of commodity in four sectors of economy, environment, society and culture.

Abstract: The present invention relates to a method for preparing a recombinant microorganism simultaneously comprising genes encoding enzymes used in the biosynthesis pathway of 6-aminocaproic acid, which is a precursor of caprolactam, biosynthesizing 6-aminocaproic acid from the microorganism, and producing the same so as to synthesize caprolactam.

Abstract: Provided is a dry electrode for detecting a bio-signal, comprising a body part; a protrusion part formed on one surface of the body part; and a coating part formed on an end surface of the protrusion part, wherein the body part and the protrusion part comprise a conductive silicone, and the coating part comprises Ag, AgCl, and, optionally, 3-aminopropyltriethoxysilane.

Abstract: A linker-drug represented by formula (I) or a pharmaceutically acceptable salt or solvate thereof is provided. In formula (I), C is a conjugator, L is a linker unit, D is a toxin unit, and n is an integer ranging from 1 to 4. The structure of the conjugator is represented by formula (II). In formula (II), X is a leaving group, each of R1 and R2 is independently a single bond or —NH—, and Z is substituted aryl, heteroaryl, linear alkyl, cycloalkyl, heterocycloalkyl, or a combination thereof. The antibody is conjugated to the linker unit through a cysteine residue of the antibody. An antibody-drug conjugate (ADC) employing the above linker-drug is also provided.

Abstract: Provided is a continuous casting and rolling method, which includes: a continuous casting operation of producing a slab; and a rolling operation of pressing the slab after a front end portion of the slab passes a first rolling stand into which the front end portion of the slab, which is provided as a continuous body to the slab produced in the continuous casting operation, initially enters.

Abstract: An electrical stimulation and bio-potential measurement device is provided. The electrical stimulation and bio-potential measurement device comprises at least one electrode module which comes into contact with the scalp of a user, a current supply unit, connected to the at least one electrode module, for supplying a current to the at least one electrode module so that the at least one electrode module can apply electrical stimulation to the user, and a signal processing unit, connected to the at least one electrode module, for processing bio-potential signals detected by the at least one electrode module, wherein the current supply unit comprises at least one switch which is arranged between the at least one electrode module and a voltage source for supplying the current.

Abstract: Provided are an ancillary device for an electrical stimulation device and an electrical stimulation device. The ancillary device is usable for an electrical stimulation device including at least one electrode that contacts the head of a user to apply a current to the head of a user, and includes a reverse current supplier that contacts the at least one electrode of the electrical stimulation device, and a controller that controls the reverse current supplier such that a reverse current is supplied to the at least one electrode to neutralize the at least one electrode.

Abstract: Provided is an electrical stimulation device. The electrical stimulation device includes a first electrode that contacts a first portion of the head of a user to apply a current to the head of the user, a second electrode that contacts a second portion that is different from the first portion of the head of the user to apply a current to the head of the user, a controller that performs a control such that polarities of the first electrode and the second electrode can be changed based on a reference comprising at least one of a reference time, a reference pH index, and a reference number of uses.

Abstract: Disclosed is an electrical stimulation device. The electrical stimulation device includes at least one electrode unit that contacts the head of a user to apply a current to the head of the user, and a current providing module that provides a current to the at least one electrode unit, wherein the current providing module includes a plurality of pads disposed on a path for providing the current to the at least one electrode unit to be spaced apart from each other, and wherein the current providing module provides the current to the at least one electrode unit if the plurality of pads are connected to each other by a conductive material.

Abstract: Provided are an ancillary device for an electrical stimulation device and an electrical stimulation device. The ancillary device is usable for an electrical stimulation device including at least one electrode that contacts the head of a user to apply a current to the head of a user, and includes a reverse current supplier that contacts the at least one electrode of the electrical stimulation device, and a controller that controls the reverse current supplier such that a reverse current is supplied to the at least one electrode to neutralize the at least one electrode.

Abstract: The present invention relates to a target-aiming drug delivery system for diagnosis and treatment of cancer containing liposome labeled with peptides which specifically targets interleukin-4 receptors, and a manufacturing method thereof. The liposome which contains anticancer drugs labeled with IL4RPep peptides prepared in accordance with the present invention can deliver drugs to cancer cells in which IL-4 receptors are overexpressed by IL4RPep peptides which specifically bind to IL-4 receptors, and the drug delivery can recognize cancer cells specifically by a label. Thus, IL4RPep peptides can increase the effect of drugs only on cancer tissues and at the same time significantly reduce the side effects on normal tissues, which makes possible in vivo(molecular) imaging and early diagnosis of tumors.

Abstract: The present invention relates to a snow ice maker, comprising a coupling shaft (40) assembly wherein refrigerant injection capillary tubes (20) and a refrigerant gas outlet tube (30) are arranged in a main passage (41), and the passage (41) is closed at a welding part (43) as a result of the capillary tubes (20) and a refrigerant gas inlet tube being simultaneously provided. The refrigerant injection capillary tubes (20) comprise ends (22) arranged in proximity to an injecting position inside a cooling drum, and the refrigerant injection capillary tubes (20) are arranged by collecting the refrigerant injection capillary tubes (20) in the passage (41) of the coupling shaft (40); extending the refrigerant injection capillary tubes (20) to the outside of the cooling drum; combining the refrigerant injection capillary tubes (20) at a multiple connection part (21); and directly connecting the refrigerant injection capillary tubes (20) to a refrigerant supply tube (52) of a refrigerant compressor.

Abstract: The disclosure provides a recipe for in-situ gel, formed by dissolving at least one polymer and at least one gel prevention agent in a polar solvent to form a solution and placing the solution in a condition for in-situ forming gels. The disclosure also provides an implant and a drug delivery system formed by the recipe.

Abstract: Disclosed are a hybrid cord produced by plying and twisting high modulus yarns and polyamide monofilaments, and a tire including the same. More specifically, disclosed is a method of producing a hybrid cord having a clear core-covering structure including a core comprising a polyamide monofilament and a covering spirally twisted around the core and comprising a high modulus yarn. The hybrid cord can clearly control the modulus ratio in each area, improving production efficiency of the cord and processability of the tire and reducing deviations of uniformity and driving performance. In addition, the tire using the hybrid cord reduces tire deformation during driving, thus satisfying both driving performance and comfort.

Abstract: An antibody-drug conjugate (ADC) of formula (I) or a pharmaceutically acceptable salt or solvate thereof is provided. In formula (I), p is an integer ranging from 1 to 26, A is an antibody, and -(L-D) is a linker-drug unit. L is a linker unit having a glycopeptide, and D is a drug unit. The antibody is conjugated to the linker unit through a cysteine residue of the antibody. A method for forming an antibody-drug conjugate (ADC) is also provided.

Abstract: A continuous casting and rolling apparatus according to one embodiment of the present invention comprises: a continuous casting apparatus for producing a steel sheet; a roller, linked to the continuous casting apparatus, for receiving the steel sheet; and a push heat unit, connected to the continuous casting apparatus and/or the roller, for selectively carrying outing heating work or removal work with respect to a portion of the steel sheet. Also, a continuous casting and rolling method according to another embodiment of the present invention may comprise: a continuous casting step for producing a steel sheet; and a selective performance step for selectively carrying out heating work or removal work with respect to a portion of the steel sheet.

Abstract: The present invention provides a method for preparing a water insoluble gel composition comprising: mixing a water soluble polysaccharide, an epoxy cross-linking agent, an alkaline compound and a solvent; and drying the thus obtained mixture at 1 to 30° C. under vacuum to remove the solvent, and a water insoluble gel composition.

Abstract: A continuous casting and rolling apparatus according to one embodiment of the present invention provides: a continuous caster for generating a steel sheet; a first rolling unit associated with the continuous caster; and a second rolling unit which is spaced apart in the outlet of the first rolling unit and comprises: a rolling mill for pressing down the steel sheet; and a cutter for cutting a portion of the steel sheet, wherein the cutter is spaced from the second rolling unit by a length corresponding to the length of the steel sheet discharged in an at least discontinuous rolling mode, and may comprise a cut withdrawal unit provided between the first rolling unit and the second rolling unit.