Patents by Inventor JU-MING WANG

JU-MING WANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12152070
    Abstract: The present invention provides a PTX3 monoclonal antibody or antibody Fab fragment thereof and use thereof. The aforementioned monoclonal antibody or antibody Fab fragment thereof specifically inhibit or slow down the binding of PTX3 to the PTX3 receptor, and may be used for a kit and method for detecting PTX3, and a pharmaceutical composition which inhibits or slows down diseases or symptoms associated with PTX3 and PTX3 receptor binding, and a use thereof.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: November 26, 2024
    Assignee: Ohealth Biopharmaceutical (Suzhou) Co., Ltd.
    Inventors: Ju-Ming Wang, I-Chen Lee, Yu-Wei Hsiao, Jhih-Ying Chi, Jyun-yi Du, Hsin-Yin Liang, Chao-chun Cheng, Chiung-Yuan Ko, Feng-Wei Chen, Jhih-Yun Liu
  • Publication number: 20220119507
    Abstract: The present invention provides a PTX3 monoclonal antibody or antibody Fab fragment thereof and use thereof. The aforementioned monoclonal antibody or antibody Fab fragment thereof specifically inhibit or slow down the binding of PTX3 to the PTX3 receptor, and may be used for a kit and method for detecting PTX3, and a pharmaceutical composition which inhibits or slows down diseases or symptoms associated with PTX3 and PTX3 receptor binding, and a use thereof.
    Type: Application
    Filed: September 13, 2019
    Publication date: April 21, 2022
    Inventors: Ju-Ming Wang, I-Chen Lee, Yu-Wei Hsiao, Jhih-Ying Chi, Jyun-yi Du, Hsin-Yin Liang, Chao-chun Cheng, Chiung-Yuan Ko, Feng-Wei Chen, Jhih-Yun Liu
  • Patent number: 10421797
    Abstract: The present invention relates to a short peptide-based therapeutic agent and a medicinal composition including the same for inhibiting activities of cancer cells, which includes at least one short peptide listed as SEQ ID NOs: 1 and 2, either of which is unglycosylated and has no more than 40 amino acid residues, thereby specifically reducing or inhibiting activities of cancer cells such as the cancer cell proliferation, cancer stemness, cell migration, cancer cell invasion, metastasis or drug resistance.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: September 24, 2019
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Ju-Ming Wang, Yu-Wei Hsiao, Jhih-Ying Chi
  • Publication number: 20180002400
    Abstract: The present invention relates to a short peptide-based therapeutic agent and a medicinal composition including the same for inhibiting activities of cancer cells, which includes at least one short peptide listed as SEQ ID NOs: 1 and 2, either of which is unglycosylated and has no more than 40 amino acid residues, thereby specifically reducing or inhibiting activities of cancer cells such as the cancer cell proliferation, cancer stemness, cell migration, cancer cell invasion, metastasis or drug resistance.
    Type: Application
    Filed: September 6, 2017
    Publication date: January 4, 2018
    Inventors: Ju-Ming WANG, Yu-Wei HSIAO, Jhih-Ying CHI
  • Patent number: 9802998
    Abstract: The present invention relates to a short peptide-based therapeutic agent and a medicinal composition including the same for inhibiting activities of cancer cells, which includes at least one short peptide listed as SEQ ID NOs: 1 and 2, either of which is unglycosylated and has no more than 40 amino acid residues, thereby specifically reducing or inhibiting activities of cancer cells such as the cancer cell proliferation, cancer stemness, cell migration, cancer cell invasion, metastasis or drug resistance.
    Type: Grant
    Filed: September 1, 2015
    Date of Patent: October 31, 2017
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Ju-Ming Wang, Yu-Wei Hsiao, Jhih-Ying Chi
  • Patent number: 9610325
    Abstract: The invention relates to a method for inhibiting euPTX3 to treat nasopharyngeal carcinoma by an amino acid sequence, comprising administering an effective amount of the amino acid sequence to a subject in need. The amino acid sequence can be used to inhibit euPTX3 from promoting the migration and invasion of nasopharyngeal carcinoma cells, promoting angiogenesis and inhibiting macrophage phagocytosis to further treat nasopharyngeal carcinoma.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: April 4, 2017
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Ju-Ming Wang, Yu-Wei Hsiao, Jhih-Ying Chi, Shao-Ming Wang
  • Publication number: 20160347800
    Abstract: The present invention relates to a short peptide-based therapeutic agent and a medicinal composition including the same for inhibiting activities of cancer cells, which includes at least one short peptide listed as SEQ ID NOs: 1 and 2, either of which is unglycosylated and has no more than 40 amino acid residues, thereby specifically reducing or inhibiting activities of cancer cells such as the cancer cell proliferation, cancer stemness, cell migration, cancer cell invasion, metastasis or drug resistance.
    Type: Application
    Filed: September 1, 2015
    Publication date: December 1, 2016
    Inventors: Ju-Ming WANG, Yu-Wei HSIAO, Jhih-Ying CHI
  • Publication number: 20150025018
    Abstract: The invention relates to a method for inhibiting euPTX3 to treat nasopharyngeal carcinoma by an amino acid sequence, comprising administering an effective amount of the amino acid sequence to a subject in need. The amino acid sequence can be used to inhibit euPTX3 from promoting the migration and invasion of nasopharyngeal carcinoma cells, promoting angiogenesis and inhibiting macrophage phagocytosis to further treat nasopharyngeal carcinoma.
    Type: Application
    Filed: October 3, 2014
    Publication date: January 22, 2015
    Inventors: JU-MING WANG, YU-WEI HSIAO
  • Publication number: 20140364374
    Abstract: The invention relates to an amino acid sequence for inhibiting PTX3 to treat nasopharyngeal carcinoma. It can be used to inhibit PTX3 from promoting the migration and invasion of nasopharyngeal carcinoma cells, promoting angiogenesis and inhibiting macrophage phagocytosis to further treat nasopharyngeal carcinoma.
    Type: Application
    Filed: October 2, 2013
    Publication date: December 11, 2014
    Applicant: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: JU-MING WANG, YU-WEI HSIAO