Patents by Inventor Jua Choi

Jua Choi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Post-transplantation prophylaxis and treatments for antibody-mediated rejection of solid organ transplant
    Patent number: 11865175
    Abstract: Provided herein are methods for treating, inhibiting, reducing the likelihood of and/or reducing the severity of antibody-mediated rejection (ABMR) in a subject with organ transplantation, by selecting a subject that has undergone an organ transplant; and administering to the subject a therapeutically effective amount of intravenous immunoglobulin (IVIG) and an anti-CD20 agent to the subject after transplantation, or both before and after transplantation.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: January 9, 2024
    Assignee: Cedars-Sinai Medical Center
    Inventors: Stanley Jordan, Ashley Vo, Jua Choi
  • Methods for treating nephrotic syndrome
    Patent number: 11840576
    Abstract: Described herein are methods for treating nephrotic syndrome using an anti-CD20 antibody. In one embodiment, that anti-CD20 antibody is Obinutuzumab.
    Type: Grant
    Filed: October 11, 2021
    Date of Patent: December 12, 2023
    Assignee: Cedars-Sinai Medical Center
    Inventors: Stanley Jordan, Ashley Vo, Jua Choi
  • METHODS OF IMPROVING ORGAN FUNCTION
    Publication number: 20220265786
    Abstract: Described herein are methods for improving long-term allograft survival and long-term kidney function in subjects that have undergone kidney transplant. An effective amount of one or more complement component 1 esterase inhibitors is administered to the subject, resulting in long-term improvement on kidney allograft survival and function.
    Type: Application
    Filed: August 7, 2020
    Publication date: August 25, 2022
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Stanley Jordan, Jua Choi, Ashley A. Vo, Edmund Huang
  • METHODS FOR TREATING NEPHROTIC SYNDROME
    Publication number: 20220098317
    Abstract: Described herein are methods for treating nephrotic syndrome using an anti-CD20 antibody. In one embodiment, that anti-CD20 antibody is Obinutuzumab.
    Type: Application
    Filed: October 11, 2021
    Publication date: March 31, 2022
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Stanley Jordan, Ashley Vo, Jua Choi
  • USE OF CLAZAKIZUMAB TO DESENSITIZE AND IMPROVE RENAL TRANSPLANTATION IN HLA-SENSITIZED PATIENTS
    Publication number: 20210395358
    Abstract: Methods for desensitization of patients in need of organ transplant are provided Human leukocyte antigen-sensitized patients awaiting incompatible kidney transplant have been treated with clazakizumab to show reduced or eliminated levels of donor-specific antibodies and an improved transplant rate Clazakizumab and variants are provided for use in various embodiments of the methods. In some embodiments, clazakizumab, or its variants, is administered simultaneously or sequentially with intravenous immunoglobulin.
    Type: Application
    Filed: November 8, 2019
    Publication date: December 23, 2021
    Applicant: Cedars-Sinai Medical Center
    Inventors: Stanley C. JORDAN, Ashley VO, Noriko AMMERMAN, Jua CHOI
  • Methods for treating nephrotic syndrome
    Patent number: 11149091
    Abstract: Described herein are methods for treating nephrotic syndrome using an anti-CD20 antibody. In one embodiment, that anti-CD20 antibody is Obinutuzumab.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: October 19, 2021
    Assignee: CEDARS-SINAI MEDICAL CENTER
    Inventors: Stanley Jordan, Ashley Vo, Jua Choi
  • METHODS FOR IMPROVING ORGAN FUNCTION IN ORGAN TRANSPLANT PATIENTS
    Publication number: 20200276283
    Abstract: Described herein are methods for improving kidney function in subjects that have undergone kidney transplant. An effective amount of one or more complement component 1 esterase inhibitors is administered to the subject, resulting in long-term improvement on kidney allograft function.
    Type: Application
    Filed: September 14, 2018
    Publication date: September 3, 2020
    Applicant: Cedars-Sinai Medical Center
    Inventors: Stanley Jordan, Jua Choi, Ashley Vo
  • METHODS FOR TREATING NEPHROTIC SYNDROME
    Publication number: 20200207864
    Abstract: Described herein are methods for treating nephrotic syndrome using an anti-CD20 antibody. In one embodiment, that anti-CD20 antibody is Obinutuzumab.
    Type: Application
    Filed: December 9, 2016
    Publication date: July 2, 2020
    Applicant: Cedars-Sinai Medical Center
    Inventors: Stanley Jordan, Ashley Vo, Jua Choi
  • METHOD FOR TREATING ANTIBODY-MEDIATED REJECTION POST-TRANSPLANTATION
    Publication number: 20170174760
    Abstract: Described herein are methods for treating antibody mediated rejection of transplanted organs using inhibitors of IL-6. In one embodiment, the IL-6 inhibitor is Tocilizumab and is administered simultaneously or sequentially with intravenous immunoglobulin (IVIG).
    Type: Application
    Filed: March 2, 2017
    Publication date: June 22, 2017
    Applicant: Cedars-Sinai Medical Center
    Inventors: Stanley C. Jordan, Ashley Vo, Jua Choi
  • METHOD FOR TREATING ANTIBODY-MEDIATED REJECTION POST-TRANSPLANTATION
    Publication number: 20170022280
    Abstract: Described herein are methods for treating antibody mediated rejection of transplanted organs using inhibitors of IL-6. In one embodiment, the IL-6 inhibitor is Tocilizumab and is administered simultaneously or sequentially with intravenous immunoglobulin (IVIG).
    Type: Application
    Filed: July 25, 2016
    Publication date: January 26, 2017
    Applicant: Cedars-Sinai Medical Center
    Inventors: Stanley C. Jordan, Ashley Vo, Jua Choi