Patents by Inventor Juan A. Mantelle

Juan A. Mantelle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition and method for transdermal lidocaine delivery
    Patent number: 10307380
    Abstract: Adhesive formulations are provides for manufacturing matrix-type lidocaine patches having improved performance, manufacturability and stability.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: June 4, 2019
    Assignee: ProSolus, Inc.
    Inventor: Juan A. Mantelle
  • Transdermal drug delivery device including an occlusive backing
    Patent number: 10231938
    Abstract: A transdermal drug delivery system for the topical application of one or more active agents contained in one or more polymeric and/or adhesive carrier layers, proximate to a non-drug containing polymeric backing layer which can control the delivery rate and profile of the transdermal drug delivery system by adjusting the moisture vapor transmission rate of the polymeric backing layer.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: March 19, 2019
    Assignee: NOVEN PHARMACEUTICALS, INC.
    Inventors: David Kanios, Juan A. Mantelle, Viet Nguyen
  • Transdermal estrogen device and delivery
    Patent number: 9833419
    Abstract: Described are transdermal drug delivery systems for the transdermal administration of estrogen, comprising a polymer matrix and estrogen. Methods of making and using such systems also are described.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: December 5, 2017
    Assignee: NOVEN PHARMACEUTICALS, INC.
    Inventor: Juan Mantelle
  • Transdermal estrogen device and delivery
    Patent number: 9730900
    Abstract: Described are transdermal drug delivery systems for the transdermal administration of estrogen, comprising a polymer matrix and estrogen. Methods of making and using such systems also are described.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: August 15, 2017
    Assignee: Noven Pharmaceuticals, Inc.
    Inventor: Juan Mantelle
  • Transdermal estrogen device and delivery
    Patent number: 9724310
    Abstract: Described are transdermal drug delivery systems for the transdermal administration of estrogen, comprising a polymer matrix and estrogen. Methods of making and using such systems also are described.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: August 8, 2017
    Assignee: Noven Pharmaceuticals, Inc.
    Inventor: Juan Mantelle
  • TRANSDERMAL TESTOSTERONE DEVICE AND DELIVERY
    Publication number: 20160331762
    Abstract: Described are transdermal drug delivery systems for the transdermal administration of testosterone, comprising a polymer matrix and testosterone. Methods of making and using such systems also are described.
    Type: Application
    Filed: March 17, 2016
    Publication date: November 17, 2016
    Applicant: Noven Pharmaceuticals, Inc.
    Inventor: Juan A. Mantelle
  • TRANSDERMAL DRUG DELIVERY DEVICE INCLUDING AN OCCLUSIVE BACKING
    Publication number: 20160128949
    Abstract: A transdermal drug delivery system for the topical application of one or more active agents contained in one or more polymeric and/or adhesive carrier layers, proximate to a non-drug containing polymeric backing layer which can control the delivery rate and profile of the transdermal drug delivery system by adjusting the moisture vapor transmission rate of the polymeric backing layer.
    Type: Application
    Filed: September 11, 2015
    Publication date: May 12, 2016
    Applicant: Noven Pharmaceuticals, Inc.
    Inventors: David Kanios, Juan A. Mantelle, Viet Nguyen
  • Transdermal testosterone device and delivery
    Patent number: 9320742
    Abstract: Described are transdermal drug delivery systems for the transdermal administration of testosterone, comprising a polymer matrix and testosterone. Methods of making and using such systems also are described.
    Type: Grant
    Filed: November 23, 2010
    Date of Patent: April 26, 2016
    Assignee: NOVEN PHARMACEUTICALS, INC.
    Inventor: Juan A. Mantelle
  • TRANSDERMAL ESTROGEN DEVICE AND DELIVERY
    Publication number: 20160015655
    Abstract: Described are transdermal drug delivery systems for the transdermal administration of estrogen, comprising a polymer matrix and estrogen. Methods of making and using such systems also are described.
    Type: Application
    Filed: September 30, 2015
    Publication date: January 21, 2016
    Applicant: NOVEN PHARMACEUTICALS, INC.
    Inventor: Juan Mantelle
  • Transdermal drug delivery device including an occlusive backing
    Patent number: 9155712
    Abstract: A transdermal drug delivery system for the topical application of one or more active agents contained in one or more polymeric and/or adhesive carrier layers, proximate to a non-drug containing polymeric backing layer which can control the delivery rate and profile of the transdermal drug delivery system by adjusting the moisture vapor transmission rate of the polymeric backing layer.
    Type: Grant
    Filed: July 21, 2014
    Date of Patent: October 13, 2015
    Assignee: NOVEN PHARMACEUTICALS, INC.
    Inventors: David Kanios, Juan A. Mantelle, Viet Nguyen
  • TRANSDERMAL ESTROGEN DEVICE AND DELIVERY
    Publication number: 20150272905
    Abstract: Described are transdermal drug delivery systems for the transdermal administration of estrogen, comprising a polymer matrix and estrogen. Methods of making and using such systems also are described.
    Type: Application
    Filed: June 12, 2015
    Publication date: October 1, 2015
    Applicant: NOVEN PHARMACEUTICALS, INC.
    Inventor: Juan Mantelle
  • TRANSDERMAL DRUG DELIVERY DEVICE INCLUDING AN OCCLUSIVE BACKING
    Publication number: 20150157578
    Abstract: A transdermal drug delivery system for the topical application of one or more active agents contained in one or more polymeric and/or adhesive carrier layers, proximate to a non-drug containing polymeric backing layer which can control the delivery rate and profile of the transdermal drug delivery system by adjusting the moisture vapor transmission rate of the polymeric backing layer.
    Type: Application
    Filed: July 21, 2014
    Publication date: June 11, 2015
    Applicant: Noven Pharmaceuticals, Inc.
    Inventors: David Kanios, Juan A. Mantelle, Viet Nguyen
  • COMPOSITIONS AND METHODS FOR CONTROLLING DRUG LOSS AND DELIVERY IN TRANSDERMAL DRUG DELIVERY SYSTEMS
    Publication number: 20140243764
    Abstract: A transdermal delivery system is provided for the topical application of one or more active agents contained in one or more polymeric and/or adhesive carrier layers, proximate to a non-drug containing polymeric and/or adhesive coating that is applied to either the transdermal system's backing or release liner. The transdermal delivery device is manufactured to optimize drug loading while providing desirable adhesion to skin or mucosa as well as providing modulation of the drug delivery and profile.
    Type: Application
    Filed: February 27, 2014
    Publication date: August 28, 2014
    Applicant: Noven Pharmaceuticals, Inc.
    Inventors: David Kanios, Rod Hartwig, Juan Mantelle, David W. Houze
  • Transdermal drug delivery device including an occlusive backing
    Patent number: 8815281
    Abstract: A transdermal drug delivery system for the topical application of one or more active agents contained in one or more polymeric and/or adhesive carrier layers, proximate to a non-drug containing polymeric backing layer which can control the delivery rate and profile of the transdermal drug delivery system by adjusting the moisture vapor transmission rate of the polymeric backing layer.
    Type: Grant
    Filed: December 29, 2010
    Date of Patent: August 26, 2014
    Assignee: Noven Pharmaceuticals, Inc.
    Inventors: David Kanios, Juan A. Mantelle, Viet Nguyen
  • TRANSDERMAL ESTROGEN DEVICE AND DELIVERY
    Publication number: 20140200530
    Abstract: Described are transdermal drug delivery systems for the transdermal administration of estrogen, comprising a polymer matrix and estrogen. Methods of making and using such systems also are described.
    Type: Application
    Filed: September 12, 2013
    Publication date: July 17, 2014
    Applicant: NOVEN PHARMACEUTICALS, INC.
    Inventor: Juan Mantelle
  • COMPOSITIONS AND METHOD FOR TREATMENT OF ATTENTION DEFICIT DISORDER AND ATTENTION DEFICIT/HYPERACTIVITY DISORDER WITH METHYLPHENIDATE
    Publication number: 20140179739
    Abstract: The invention relates to a method of treating Attention Deficit Disorder (ADD) and Attention Deficit/Hyperactivity Disorder (ADHD) and compositions for topical application of methylphenidate comprising methylphenidate in a flexible, finite system wherein the methylphenidate is present in an amount sufficient to achieve substantially zero order kinetics for delivery to the skin or mucosa of a patient in need thereof over a period of time at least 10 hours.
    Type: Application
    Filed: February 27, 2014
    Publication date: June 26, 2014
    Applicant: NOVEN PHARMACEUTICALS, INC.
    Inventors: Juan Mantelle, Terese A. Dixon, David Kanios
  • Compositions and methods for delivery of amino-functional drugs
    Patent number: 8715723
    Abstract: Described are flexible, finite systems for the transdermal administration of scopolamine, comprising: (a) a polymer matrix comprising a polymer blend comprising (i) a non-functional acrylic-based polymer constituting at least about 60% by weight of the dry weight of the polymer matrix, and (ii) an amine-resistant capped silicone polymer constituting not more than about 30% by weight of the dry weight of the polymer matrix; and (b) scopolamine solubilized in the polymer matrix, wherein the flexible, finite system is substantially free of vinyl acetate and polar components. In some embodiments, the polymer matrix also comprises a non-polar penetration enhancer. Methods of making and using such flexible, finite systems also are described.
    Type: Grant
    Filed: February 26, 2007
    Date of Patent: May 6, 2014
    Assignee: Noven Pharmaceuticals, Inc.
    Inventors: David P. Kanios, Juan A. Mantelle
  • Compositions and methods for controlling drug loss and delivery in transdermal drug delivery systems
    Patent number: 8703175
    Abstract: A transdermal delivery system is provided for the topical application of one or more active agents contained in one or more polymeric and/or adhesive carrier layers, proximate to a non-drug containing polymeric and/or adhesive coating that is applied to either the transdermal system's backing or release liner. The transdermal delivery device is manufactured to optimize drug loading while providing desirable adhesion to skin or mucosa as well as providing modulation of the drug delivery and profile.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: April 22, 2014
    Assignee: Noven Pharmaceuticals, Inc.
    Inventors: David P. Kanios, Rod Hartwig, Juan A. Mantelle, David W. Houze
  • COMPOSITIONS AND METHOD FOR TREATMENT OF ATTENTION DEFICIT DISORDER AND ATTENTION DEFICIT/HYPERACTIVITY DISORDER WITH METHYLPHENIDATE
    Publication number: 20130324575
    Abstract: The invention relates to a method of treating Attention Deficit Disorder (ADD) and Attention Deficit/Hyperactivity Disorder (ADHD) and compositions for topical application of methylphenidate comprising methylphenidate in a flexible, finite system wherein the methylphenidate is present in an amount sufficient to achieve substantially zero order kinetics for delivery to the skin or mucosa of a patient in need thereof over a period of time at least 10 hours.
    Type: Application
    Filed: August 8, 2013
    Publication date: December 5, 2013
    Applicant: NOVEN PHARMACEUTICALS, INC.
    Inventors: Juan Mantelle, Terese A. Dixon, David Kanios
  • Transdermal drug delivery device including an occlusive backing
    Patent number: 8591941
    Abstract: A transdermal drug delivery system for the topical application of one or more active agents contained in one or more polymeric and/or adhesive carrier layers, proximate to a non-drug containing polymeric backing layer which can control the delivery rate and profile of the transdermal drug delivery system by adjusting the moisture vapor transmission rate of the polymeric backing layer.
    Type: Grant
    Filed: August 4, 2011
    Date of Patent: November 26, 2013
    Assignee: Noven Pharmaceuticals, Inc.
    Inventors: David Kanios, Juan A. Mantelle, Viet Nguyen