Abstract: Described herein are compound for the modulation of the G-CSF receptor. The compounds may act as agonists, antagonists, and/or mixed or partial agonists/antagonists of G-CSF. Further provided herein are methods of treating a condition, including, for example, a neurodegenerative disease, by administering a compound as detailed herein.

Abstract: A photovoltaic (PV) module cleaning system can include a robotic cleaning device and a support system. The support system can be configured to provide a metered fill to the robotic cleaning device.

Abstract: In accordance with an embodiment of the present invention, a method of controlling current through a transistor includes measuring a voltage across the transistor, measuring a current through the transistor, determining a safe operating current for the measured voltage across the transistor, and adjusting a voltage of a control node of the transistor using a feedback controller until the measured current through the transistor is not greater than the determined safe operating current.

Abstract: The compositions and methods of the disclosure particularly target the divalent metal transporter expressed on olfactory nerve terminals to transport divalent cation-coated or cation-containing nanoparticles to all regions of brain. It has been found that such divalent cation-containing nanoparticles, including those nanoparticles comprising manganese have affinity for the metal transport receptor proteins. Although this receptor has particular affinity for manganese, it is contemplated that other divalent ions, including magnesium, calcium, and the like may also be bound to such receptors leading to transport of the nanoparticles into the intracellular cytoplasm. Nanoparticles have been developed, therefore, as vehicles for parenteral delivery of genes, proteins and drugs.

Abstract: The present invention relates to the use of umbilical cord blood cells from a donor or patient to provide neural cells which may be used in transplantation. The isolated cells according to the present invention may be used to effect autologous and allogeneic transplantation and repair of neural tissue, in particular, tissue of the brain and spinal cord and to treat neurodegenerative diseases of the brain and spinal cord.

Abstract: The purpose of the claimed invention is to have a protective internal structure using multiple corrugated paperboard inserts that will fit into a RSC (regular slotted container) case. These inserts and the internal structure that it creates, enable a user to ship their product via common or contract carrier without damage to the user's product.

Abstract: The present invention relates to the use of umbilical cord blood cells from a donor or patient to provide neural cells which may be used in transplantation. The isolated cells according to the present invention may be used to effect autologous and allogeneic transplantation and repair of neural tissue, in particular, tissue of the brain and spinal cord and to treat neurodegenerative diseases of the brain and spinal cord.

Abstract: A photovoltaic (PV) module cleaning system can include a robotic cleaning device and a support system. The support system can be configured to provide a metered fill to the robotic cleaning device.

Abstract: The present invention discloses a method for modulating freezing of a liquid substance, said liquid substance being in the presence of a gas phase, the method comprising modulating the temperature of the liquid substance, of the gas phase or of both, and controlling the concentration of vapor of the substance present in the gas phase. The invention further comprises a method for preservation, for example, food or other biological material, and an apparatus for putting said method into practice.

Abstract: Systems and methods for a riser coupling are disclosed. A riser sensor unit for sensing engagement of a riser tool with a riser coupling includes a first sensor attached to a sub of the riser tool. The first sensor is configured to generate a first signal upon detecting contact with the riser coupling, and an intrinsic safety barrier is configured to transmit the first signal to a control system.

Abstract: The compositions and methods of the disclosure particularly target the divalent metal transporter expressed on olfactory nerve terminals to transport divalent cation-coated or cation-containing nanoparticles to all regions of brain. It has been found that such divalent cation-containing nanoparticles, including those nanoparticles comprising manganese have affinity for the metal transport receptor proteins. Although this receptor has particular affinity for manganese, it is contemplated that other divalent ions, including magnesium, calcium, and the like may also be bound to such receptors leading to transport of the nanoparticles into the intracellular cytoplasm. Nanoparticles have been developed, therefore, as vehicles for parenteral delivery of genes, proteins and drugs.

Abstract: The compositions and methods of the disclosure particularly target the divalent metal transporter expressed on olfactory nerve terminals to transport divalent cation-coated or cation-containing nanoparticles to all regions of brain. It has been found that such divalent cation-containing nanoparticles, including those nanoparticles comprising manganese have affinity for the metal transport receptor proteins. Although this receptor has particular affinity for manganese, it is contemplated that other divalent ions, including magnesium, calcium, and the like may also be bound to such receptors leading to transport of the nanoparticles into the intracellular cytoplasm. Nanoparticles have been developed, therefore, as vehicles for parenteral delivery of genes, proteins and drugs.

Abstract: A solar module cleaner can be configured for cleaning reflective surfaces of solar concentrator reflectors. The cleaner can include at least one cleaning module having a cleaning surface extending in a curved configuration corresponding to a curvature of the solar concentrator reflector. The cleaning surface can be configured to displace debris resting on the reflective surface. The cleaner can include fluid delivery devices for discharging a cleaning fluid onto the reflective surface. The cleaner can be configured to clean solar energy receivers associated with a solar concentrator reflector. Additionally, the cleaner can be configured to simultaneously clean a plurality of parallel solar concentrator reflectors. Optionally, the cleaner can be configured to simultaneously clean a plurality of solar energy receivers and a plurality of solar energy concentrators.

Abstract: A photovoltaic (PV) module cleaning system can include a robotic cleaning device and a support system. The support system can be configured to provide a metered fill to the robotic cleaning device. In some embodiments, the robotic cleaning device and include a curved cleaning head. Various techniques for deploying a robotic cleaning device on PV modules include out-and-back, leapfrog, among others.

Abstract: The present invention relates to a process for preparing a graphene nanoribbon, which comprises: (a) providing at least one aromatic monomer compound which is selected from at least one polycyclic aromatic monomer compound, at least one oligo phenylene aromatic monomer compound, or combinations thereof, on a solid substrate, (b) polymerization of the aromatic monomer compound so as to form at least one polymer on the surface of the solid substrate, (c) at least partially cyclodehydrogenating the one or more polymers of step (b), wherein at least step (b) is carried out at a total pressure p(total) of at least 1×10?9 mbar; and a partial oxygen pressure p(O2) and partial water pressure p(H2O) which satisfy the following relation: p(O2)×p(H20)<3×10?14 mbar2.

Abstract: This invention identifies the plant MINIYO (IYO) gene and the AtRTR1 gene for the initiation of cell differentiation in all plant meristems and in embryogenesis. This invention relates methods for generating transgenic plants in which expression of the IYO and/or AtRTR1 genes or their orthologous genes is modified to advancing or delaying the onset of differentiation in one or more meristems of the plant.

Abstract: The compositions and methods of the disclosure particularly target the divalent metal transporter expressed on olfactory nerve terminals to transport divalent cation-coated or cation-containing nanoparticles to all regions of brain. It has been found that such divalent cation-containing nanoparticles, including those nanoparticles comprising manganese have affinity for the metal transport receptor proteins. Although this receptor has particular affinity for manganese, it is contemplated that other divalent ions, including magnesium, calcium, and the like may also be bound to such receptors leading to transport of the nanoparticles into the intracellular cytoplasm. Nanoparticles have been developed, therefore, as vehicles for parenteral delivery of genes, proteins and drugs.