Patents by Inventor Juan Alejandro Vidal

Juan Alejandro Vidal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Host cells expressing recombinant human erythropoietin
    Patent number: 6777205
    Abstract: The gene coding for human erythropoietin (EPO) was obtained from human genomic DNA. Thc gene used does not include sequences from regions at i 5′ of the first translated ATG and ii 3′ of the stop codon of the EPO gene. The gene was cloned into an expression plasmid for eukaryotic cells that have as sole expression control elements the early promoter of the SV40 virus and its polyadenylation signal. Recombinant cells resulting from transfection with genetic constructs used provide an unexpectedly high level of protein expression of 50 mg of recombinant EPO per liter of culture medium per day.
    Type: Grant
    Filed: November 6, 2001
    Date of Patent: August 17, 2004
    Assignee: Sterrenbeld Biotechnologie North America, Inc.
    Inventors: Carlos Miguel Carcagno, Marcelo Eduardo Criscuolo, Carlos Alberto Melo, Juan Alejandro Vidal