Patents by Inventor Juan Antonio MARCHAL CORRALES

Juan Antonio MARCHAL CORRALES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HYDROGELS FOR USE IN SKIN TISSUE ENGINEERING
    Publication number: 20230372575
    Abstract: The present invention relates to hydrogels that include native skin components, as well as to bio-inks, compositions and dressings based on the same. Furthermore, the invention relates to their uses in regenerative medicine, in particular, in the regeneration, repair and replacement of skin tissue, and a method for obtaining the hydrogels of the invention.
    Type: Application
    Filed: May 22, 2023
    Publication date: November 23, 2023
    Inventors: Juan Antonio MARCHAL CORRALES, Elena LÓPEZ RUIZ, Patricia GÁLVEZ MARTÍN, Carlos CHOCARRO WRONA
  • A MEDICAL APPARATUS FOR THE NON-INVASIVE TRANSMISSION OF FOCUSSED SHEAR WAVES TO IMPACT CELLULAR BEHAVIOUR
    Publication number: 20230347181
    Abstract: The present invention refers to a medical apparatus that allows to generate, non-invasively and at a requested depth shear waves of controlled frequency and amplitude. The purpose is to impact via mechanotransduction on cellular behavior, i.e. cell proliferation and cell migration. The aim is to aide classical tumor therapy for instance by rendering cells more receptive to drugs, or by gaining time during chemotherapy by reducing cell migration and hence slowing down the metastatic process.
    Type: Application
    Filed: August 16, 2021
    Publication date: November 2, 2023
    Inventors: Guillermo Rus Carlborg, Juan Antonio Marchal Corrales, Juan Soler Vizcaino, Juan Manuel Melchor Rodriguez, Antonio Manuel Callejas Zafra, Miguel Riveiro Taboada, Gema Jimenez Gonzalez, Ralph Sinkus
  • MULTIFUNCTIONAL NANOPARTICLES FOR THERAGNOSIS
    Publication number: 20230248847
    Abstract: The present invention relates to the field of medicine, particularly to functionalised nanoparticles (NP) for use in cancer therapy (treatment or diagnosis), to pharmaceutical compositions or nano devices comprising same, and also to a method for obtaining said functionalised nanoparticles. The nanoparticles described in the present invention can be used specifically to treat cancer efficiently, as same can selectively detect tumour cells.
    Type: Application
    Filed: October 6, 2022
    Publication date: August 10, 2023
    Inventors: Rosario María SÁNCHEZ MARTÍN, Juan Antonio MARCHAL CORRALES, Juan José DÍAZ MOCHÓN, Victoria CANO CORTÉS, Saúl Abenhamar NAVARRO MARCHAL, Maria Paz RUIZ BLAS
  • CANCER TREATMENT
    Publication number: 20230089740
    Abstract: The present invention relates to compositions, methods, uses and kits for treating cancer. The present invention relates to methods for minimising the progression of cancer in a subject, the method comprising administering to the subject therapeutically effective amounts of chymotrypsinogen and trypsinogen, thereby minimising the progression of cancer in the subject. In particular, the methods provide a means for treating cancer by reducing the number of cancer stem cells in the subject.
    Type: Application
    Filed: June 3, 2022
    Publication date: March 23, 2023
    Applicant: Propanc Pty Ltd
    Inventors: Macarena Perán Quesada, Julian Kenyon, Juan Antonio Marchal Corrales, Maria Angel Garcia Chaves
  • GENE THERAPY WITH THE GENES HOKD AND LDRB FOR CANCER TREATMENTS
    Publication number: 20220211872
    Abstract: The invention relates to the isolated RNA or DNA polynucleotides hokD and ldrB for use in medicine, particularly in gene therapy for cancer treatment. Also described are compositions comprising such polynucleotides or related genetic structures, and a method for treating proliferative disorders, preferably cancer.
    Type: Application
    Filed: May 15, 2020
    Publication date: July 7, 2022
    Inventors: Houria BOULAIZ TASSI, Juan Antonio MARCHAL CORRALES, Carmen GRIÑÁN LISÓN, Gema JIMÉNEZ GONZÁLEZ, Yaiza JIMÉNEZ MARTÍNEZ
  • Cancer treatment
    Patent number: 11376313
    Abstract: The present invention relates to compositions, methods, uses and kits for treating cancer. The present invention relates to methods for minimising the progression of cancer in a subject, the method comprising administering to the subject therapeutically effective amounts of chymotrypsinogen and trypsinogen, thereby minimising the progression of cancer in the subject. In particular, the methods provide a means for treating cancer by reducing the number of cancer stem cells in the subject.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: July 5, 2022
    Assignee: PROPANC PTY LTD
    Inventors: Macarena Perán Quesada, Julian Kenyon, Juan Antonio Marchal Corrales, Maria Angel Garcia Chaves
  • MULTIFUNCTIONAL NANOPARTICLES FOR THERAGNOSIS
    Publication number: 20210162077
    Abstract: The present invention relates to the field of medicine, particularly to functionalised nanoparticles (NP) for use in cancer therapy (treatment or diagnosis), to pharmaceutical compositions or nano devices comprising same, and also to a method for obtaining said functionalised nanoparticles. The nanoparticles described in the present invention can be used specifically to treat cancer efficiently, as same can selectively detect tumour cells.
    Type: Application
    Filed: April 12, 2019
    Publication date: June 3, 2021
    Inventors: Rosario María SÁNCHEZ MARTÍN, Juan Antonio MARCHAL CORRALES, Juan José DÍAZ MOCHÓN, Victoria CANO CORTÉS, Saúl Abenhamar NAVARRO MARCHAL, Maria Paz RUIZ BLAS
  • Phenol derivatives to treat cancer
    Patent number: 10414745
    Abstract: The present invention relates to compounds of general formula (I) wherein R1-R8 take various meanings, pharmaceutical compositions containing them and their use in medicine, particularly for the treatment and/or prophylaxis of cancer.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: September 17, 2019
    Assignee: FUNDACIÓN MEDINA. CENTRO DE EXCELENCIA EN INVESTIGACIÓN DE MEDICAMENTOS INNOVADORES EN ANDALUCÍA
    Inventors: Nuria De Pedro Montejo, Victor Gonzalez Menendez, Gloria Crespo Sueiro, Ignacio Perez-Victoria Moreno De Barreda, Bastien Cautain, Maria Francisca Vicente Perez, Jose Fernando Reyes Benitez, Olga Genilloud Rodriguez, Carmen Grinan Lison, Juan Antonio Marchal Corrales
  • CANCER TREATMENT
    Publication number: 20190038725
    Abstract: The present invention relates to compositions, methods, uses and kits for treating cancer. The present invention relates to methods for minimising the progression of cancer in a subject, the method comprising administering to the subject therapeutically effective amounts of chymotrypsinogen and trypsinogen, thereby minimising the progression of cancer in the subject. In particular, the methods provide a means for treating cancer by reducing the number of cancer stem cells in the subject.
    Type: Application
    Filed: January 27, 2017
    Publication date: February 7, 2019
    Inventors: Macarena Peran, Julian Kenyon, Juan Antonio Marchal Corrales, Maria Angel Garcia Chaves
  • PHENOL DERIVATIVES TO TREAT CANCER
    Publication number: 20180148427
    Abstract: The present invention relates to compounds of general formula (I) wherein R1-R8 take various meanings, pharmaceutical compositions containing them and their use in medicine, particularly for the treatment and/or prophylaxis of cancer.
    Type: Application
    Filed: April 29, 2016
    Publication date: May 31, 2018
    Applicant: FUNDACION MEDINA CENTRO DE EXCELENCIA DE MEDICAMENTOS INNOVA
    Inventors: Nuria DE PEDRO MONTEJO, Victor GONZALEZ MENENDEZ, Gloria CRESPO SUEIRO, Ignacio PEREZ-VICTORIA MORENO DE BARREDA, Bastien CAUTAIN, Maria Francisca VICENTE PEREZ, Jose Fernando REYES BENITEZ, Olga GENILLOUD RODRIGUEZ, Carmen GRINAN LISON, Juan Antonio MARCHAL CORRALES
  • CULTURE MEDIUM AND METHOD FOR ENRICHING AND MAINTAINING CANCER STEM CELLS (CSCS) USING SAID MEDIUM
    Publication number: 20170226472
    Abstract: The present invention relates to a serum-free conditioned medium that solves the drawbacks mentioned in the prior art, as it does not require prior handling of the cells, and it furthermore allows starting from a large population with no additional cost. This medium favors in vitro proliferation and conservation of the pluripotency potential that allows maintaining a state that is undifferentiated with respect to the subpopulation of cancer stem cells (CSCs) and in turn does not allow survival of the differentiated cells.
    Type: Application
    Filed: August 4, 2015
    Publication date: August 10, 2017
    Applicants: Universidad de Granada, Universidad de Jaén, Servicio Andaluz de Salud
    Inventors: Juan Antonio Marchal Corrales, Gema Jiménez González, Cynthia Morata Tarifa, María Ángel García Chaves, Macarena Perán Quesada
  • EPITHELIAL-MESENCHYMAL TRANSITION IN CIRCULATING TUMOR CELLS (CTCS) NEGATIVES FOR CYTOKERATIN (CK) EXPRESSION IN PATIENTS WITH NON-METASTATIC BREAST CANCER
    Publication number: 20160273047
    Abstract: The inventors of the present invention have surprisingly discovered that EGFR expression in nonmetastatic breast cancer patients with CK-negative CTCs could induce EMT process. A simultaneous detection of both EGFR and EMT markers (VIM and Slug) in CTCs might improve prognostic or predictive information in patients with operable breast cancer.
    Type: Application
    Filed: October 30, 2014
    Publication date: September 22, 2016
    Inventors: José Luis GARCÍA PUCHE, María José SERRANO FERNÁNDEZ, José Antonio LORENTE ACOSTA, Juan Antonio MARCHAL CORRALES, Francisco Gabriel ORTEGA SÁNCHEZ