Patents by Inventor Juan Carlos Ramírez Martínez

Juan Carlos Ramírez Martínez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable episomes based on non-integrative lentiviral vectors
    Patent number: 10294492
    Abstract: The invention relates to non-integrative lentiviral vectors and their use for the stable transgenesis of both dividing and no-dividing eukaryotic cells. The invention also provides methods for obtaining these vectors, the use of these vectors for the production of recombinant lentiviruses, and the use of these recombinant lentiviruses for obtaining a cell able to stably produce a product of interest.
    Type: Grant
    Filed: November 27, 2014
    Date of Patent: May 21, 2019
    Assignee: FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES CARIOVASCULARES CARLOS III (CNIC)
    Inventors: Juan Carlos Ramírez Martínez, Raúl Torres Ruiz, Aida García Torralba
  • STABLE EPISOMES BASED ON NON-INTEGRATIVE LENTIVIRAL VECTORS
    Publication number: 20170022519
    Abstract: The invention relates to non-integrative lentiviral vectors and their use for the stable transgenesis of both dividing and no-dividing eukaryotic cells. The invention also provides methods for obtaining these vectors, the use of these vectors for the production of recombinant lentiviruses, and the use of these recombinant lentiviruses for obtaining a cell able to stably produce a product of interest.
    Type: Application
    Filed: November 27, 2014
    Publication date: January 26, 2017
    Inventors: Juan Carlos Ramírez Martínez, Raúl Torres Ruiz, Aida García Torralba
  • BIOACTIVE SURFACE CAPABLE OF GENETICALLY MODIFYING BIOLOGICAL CELLS OR TISSUES AND USE THEREOF
    Publication number: 20140023711
    Abstract: The invention relates to a bioactive surface comprising a polymer matrix, a connecting complex comprising at least one compound covalently bound to the surface of the polymer matrix, and a gene transfer vector bound to the connecting complex, wherein the compound of the complex is covalently bound to the transfer vector using a group selected from among carboxyl, amino, isocyanate and hydroxyl. The invention also relates to the use of the bioactive surface for transferring a nucleic acid to a cell. The invention further relates to: an implantable device characterized in that at least part of the surface thereof is coated with said bioactive surface, and to the use of the implantable device for transferring a nucleic acid to a cell. In addition, the invention relates to a method for transferring a nucleic acid to a cell and to a kit for performing said method.
    Type: Application
    Filed: December 22, 2010
    Publication date: January 23, 2014
    Inventors: Manuel Angel Gonzalez De La Pena, Juan Carlos Ramirez Martinez, Anna Cifuentes, Antonio Bernad Miana, Salvador Borros Gomez, David Horna Tomas