Patents by Inventor Juan Espinoza

Juan Espinoza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10765694
    Abstract: The present invention features compositions and methods that make use of complexes comprising one or more inhibitory nucleic acids and a targeting polypeptide, wherein the targeting polypeptide consists of a cell surface receptor ligand. The compositions can be used in methods of silencing gene expression in a cell, delivering agents to a target cell, and in treating or preventing a disease or disorder in a subject.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: September 8, 2020
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Bira Arya, Purevdorj Olkhanud, Juan Espinoza
  • Publication number: 20160310609
    Abstract: The present invention features compositions and methods that make use of complexes comprising one or more inhibitory nucleic acids and a targeting polypeptide, wherein the targeting polypeptide consists of a cell surface receptor ligand. The compositions can be used in methods of silencing gene expression in a cell, delivering agents to a target cell, and in treating or preventing a disease or disorder in a subject.
    Type: Application
    Filed: July 7, 2016
    Publication date: October 27, 2016
    Inventors: Bira Arya, Purevdorj Olkhanud, Juan Espinoza
  • Patent number: 9415116
    Abstract: The present invention features compositions and methods that make use of complexes comprising one or more inhibitory nucleic acids and a targeting polypeptide, wherein the targeting polypeptide consists of a cell surface receptor ligand. The compositions can be used in methods of silencing gene expression in a cell, in delivering agents to a target cell, and in treating or preventing a disease or disorder in a subject.
    Type: Grant
    Filed: March 20, 2014
    Date of Patent: August 16, 2016
    Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Bira Arya, Purevdorj Olkhanud, Juan Espinoza
  • Publication number: 20140377179
    Abstract: The present invention features compositions and methods that make use of complexes comprising one or more inhibitory nucleic acids and a targeting polypeptide, wherein the targeting polypeptide consists of a cell surface receptor ligand. The compositions can be used in methods of silencing gene expression in a cell, in delivering agents to a target cell, and in treating or preventing a disease or disorder in a subject.
    Type: Application
    Filed: March 20, 2014
    Publication date: December 25, 2014
    Applicant: The United States of America,as represented by the Secretary, Department of Health & Human Services
    Inventors: Bira Arya, Purevdorj Olkhanud, Juan Espinoza
  • Patent number: 8703921
    Abstract: The present invention features compositions and methods that make use of complexes comprising one or more inhibitory nucleic acids and a targeting polypeptide, wherein the targeting polypeptide consists of a cell surface receptor ligand. The compositions can be used in methods of silencing gene expression in a cell, in delivering agents to a target cell, and in treating or preventing a disease or disorder in a subject.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: April 22, 2014
    Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Bira Arya, Purevdorj Olkhanud, Juan Espinoza
  • Publication number: 20110150768
    Abstract: The present invention features compositions and methods that make use of complexes comprising one or more inhibitory nucleic acids and a targeting polypeptide, wherein the targeting polypeptide consists of a cell surface receptor ligand. The compositions can be used in methods of silencing gene expression in a cell, in delivering agents to a target cell, and in treating or preventing a disease or disorder in a subject.
    Type: Application
    Filed: April 15, 2009
    Publication date: June 23, 2011
    Applicant: The United States of America, as represented by th e Secretary, Dept. of Health and Human Services
    Inventors: Bira Arya, Purevdorj Olkhanud, Juan Espinoza