Patents by Inventor Juan F. Granada
Juan F. Granada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170325948Abstract: A prosthetic mitral valve includes an anchor assembly, an annular strut frame, and a plurality of replacement leaflets secured to the annular strut frame. The anchor assembly includes a ventricular anchor, an atrial anchor, and a central portion therebetween. The annular strut frame is disposed radially within the anchor assembly. An atrial end of the annular strut frame is attached to the anchor assembly such that a ventricular end of the annular strut frame is spaced away from the anchor assembly.Type: ApplicationFiled: August 4, 2017Publication date: November 16, 2017Inventors: Dan WALLACE, Spencer NOE, Peter GREGG, Juan F. GRANADA
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Publication number: 20170245991Abstract: A method of delivering a prosthetic mitral valve includes delivering a distal anchor from a delivery sheath such that the distal anchor self-expands inside a first heart chamber on a first side of the mitral valve annulus, pulling proximally on the distal anchor such that the distal anchor self-aligns within the mitral valve annulus and the distal anchor rests against tissue of the ventricular heart chamber, and delivering a proximal anchor from the delivery sheath to a second heart chamber on a second side of the mitral valve annulus such that the proximal anchor self-expands and moves towards the distal anchor to rest against tissue of the second heart chamber. The self-expansion of the proximal anchor captures tissue of the mitral valve annulus therebetween.Type: ApplicationFiled: February 3, 2017Publication date: August 31, 2017Inventors: Juan F. GRANADA, Gary ERZBERGER, Michael P. CORCORAN, Dan WALLACE, Matteo MONTORFANO, Alaide CHIEFFO, Robert LaDUCA
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Patent number: 9561103Abstract: A method of delivering a prosthetic mitral valve includes delivering a distal anchor from a delivery sheath such that the distal anchor self-expands inside a first heart chamber on a first side of the mitral valve annulus, pulling proximally on the distal anchor such that the distal anchor self-aligns within the mitral valve annulus and the distal anchor rests against tissue of the ventricular heart chamber, and delivering a proximal anchor from the delivery sheath to a second heart chamber on a second side of the mitral valve annulus such that the proximal anchor self-expands and moves towards the distal anchor to rest against tissue of the second heart chamber. The self-expansion of the proximal anchor captures tissue of the mitral valve annulus therebetween.Type: GrantFiled: January 31, 2014Date of Patent: February 7, 2017Assignee: Cephea Valve Technologies, Inc.Inventors: Juan F. Granada, Gary Erzberger, Michael P. Corcoran, Dan Wallace, Matteo Montorfano, Alaide Chieffo, Robert LaDuca
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Patent number: 9554899Abstract: A prosthetic mitral valve comprising an expandable anchor comprising a first anchor, a central portion and a second anchor; wherein the first anchor comprises a first outer frame and a second outer frame, the first outer frame comprising a plurality of first arcs joined together, and the second outer frame comprising a plurality of second arcs joined together, wherein the plurality of first arcs are out of phase relative to the plurality of second arcs when the first anchor is viewed in an end view from the first anchor to the second anchor; and a plurality of replacement leaflets secured to the expandable anchor.Type: GrantFiled: April 2, 2015Date of Patent: January 31, 2017Assignee: Cephea Valve Technologies, Inc.Inventors: Juan F. Granada, Gary Erzberger, Michael P. Corcoran, Dan Wallace, Matteo Montorfano, Alaide Chieffo, Thierry Thaure
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Publication number: 20160256270Abstract: An implant system may include a delivery sheath having an actuator mechanism, an anchoring assistance device including an expandable scaffold including a mid-body section, a cusp interface section, and a crown end arrangement, and a replacement heart valve implant. The cusp interface section includes a plurality of loop portions arranged at radial intervals about the expandable scaffold. Each loop portion is circumferentially spaced apart from another loop portion by a region having a deployment ring, the region being configured to span a commissure of the aortic valve and extending distally a shorter distance from the distal end than the loop portions. An elongate deployment member is configured to releasably engage with the deployment rings to actuate the expandable scaffold from a delivery configuration to a deployed configuration. The replacement heart valve implant is configured to be at least partially disposed within the expandable scaffold in the deployed configuration.Type: ApplicationFiled: March 3, 2016Publication date: September 8, 2016Inventors: Martyn G. Folan, Juan F. Granada
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Publication number: 20160158000Abstract: Prosthetic mitral valves and their methods of manufacture and use.Type: ApplicationFiled: April 2, 2015Publication date: June 9, 2016Inventors: Juan F. GRANADA, Gary ERZBERGER, Michael P. CORCORAN, Dan WALLACE, Matteo MONTORFANO, Alaide CHIEFFO, Thierry Thaure, Aaron GROGAN, Peter Gregg
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Publication number: 20150209139Abstract: A prosthetic mitral valve comprising an expandable anchor comprising a first anchor, a central portion and a second anchor; wherein the first anchor comprises a first outer frame and a second outer frame, the first outer frame comprising a plurality of first arcs joined together, and the second outer frame comprising a plurality of second arcs joined together, wherein the plurality of first arcs are out of phase relative to the plurality of second arcs when the first anchor is viewed in an end view from the first anchor to the second anchor; and a plurality of replacement leaflets secured to the expandable anchor.Type: ApplicationFiled: April 2, 2015Publication date: July 30, 2015Inventors: Juan F. GRANADA, Gary ERZBERGER, Michael P. CORCORAN, Dan WALLACE, Matteo MONTORFANO, Alaide CHIEFFO, Thierry Thaure
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Publication number: 20150025623Abstract: A method of delivering a prosthetic mitral valve includes delivering a distal anchor from a delivery sheath such that the distal anchor self-expands inside a first heart chamber on a first side of the mitral valve annulus, pulling proximally on the distal anchor such that the distal anchor self-aligns within the mitral valve annulus and the distal anchor rests against tissue of the ventricular heart chamber, and delivering a proximal anchor from the delivery sheath to a second heart chamber on a second side of the mitral valve annulus such that the proximal anchor self-expands and moves towards the distal anchor to rest against tissue of the second heart chamber. The self-expansion of the proximal anchor captures tissue of the mitral valve annulus therebetween.Type: ApplicationFiled: January 31, 2014Publication date: January 22, 2015Inventors: Juan F. GRANADA, Gary ERZBERGER, Michael P. CORCORAN, Dan WALLACE, Matteo MONTORFANO, Alaide CHIEFFO, Robert LaDUCA
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Patent number: 8870948Abstract: A prosthetic mitral valve includes a proximal anchor, a distal anchor, and a central portion therebetween. The proximal and distal anchors each include a first outer frame and a second outer frame. The first outer frame includes a plurality of first arcs joined together, and the second outer frame includes a plurality of second arcs joined together. The plurality of first arcs are out of phase relative to the plurality of second arcs.Type: GrantFiled: January 31, 2014Date of Patent: October 28, 2014Assignee: Cephea Valve Technologies, Inc.Inventors: Gary Erzberger, Michael P. Corcoran, Juan F. Granada, Dan Wallace, Matteo Montorfano, Alaide Chieffo, Thierry Thaure
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Publication number: 20140257476Abstract: The present invention comprises a novel and safer mechanism of deployment using a self-positioning, self-centering, and self-anchoring method. To embody the present invention, a disk-based valve apparatus allowing the repositioning and retrieval of the implantable valve while working on a dysfunctional valve structure is disclosed. The disk-based valve apparatus may comprise one or more disks, either proximal or distal, a valve-housing component and a valve component. The one or more disks may be either proximal or distal, may be either connected to each other or disconnected from each other and may either be symmetrical or have different shapes and dimensions. The disk-based valve apparatus may be self anchoring, such as anchored by pressure from the one or more disk, or may be anchored using any anchoring.Type: ApplicationFiled: May 19, 2014Publication date: September 11, 2014Inventors: Matteo MONTORFANO, Alaide CHIEFFO, Juan F. GRANADA
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Patent number: 8728155Abstract: The present invention comprises a novel and safer mechanism of deployment using a self-positioning, self-centering, and self-anchoring method. To embody the present invention, a disk-based valve apparatus allowing the repositioning and retrieval of the implantable valve while working on a dysfunctional valve structure is disclosed. The disk-based valve apparatus may comprise one or more disks, either proximal or distal, a valve-housing component and a valve component. The one or more disks may be either proximal or distal, may be either connected to each other or disconnected from each other and may either be symmetrical or have different shapes and dimensions. The disk-based valve apparatus may be self anchoring, such as anchored by pressure from the one or more disk, or may be anchored using any anchoring.Type: GrantFiled: September 20, 2013Date of Patent: May 20, 2014Assignee: Cephea Valve Technologies, Inc.Inventors: Matteo Montorfano, Alaide Chieffo, Juan F. Granada
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Publication number: 20140025164Abstract: The present invention comprises a novel and safer mechanism of deployment using a self-positioning, self-centering, and self-anchoring method. To embody the present invention, a disk-based valve apparatus allowing the repositioning and retrieval of the implantable valve while working on a dysfunctional valve structure is disclosed. The disk-based valve apparatus may comprise one or more disks, either proximal or distal, a valve-housing component and a valve component. The one or more disks may be either proximal or distal, may be either connected to each other or disconnected from each other and may either be symmetrical or have different shapes and dimensions. The disk-based valve apparatus may be self anchoring, such as anchored by pressure from the one or more disk, or may be anchored using any anchoring.Type: ApplicationFiled: September 20, 2013Publication date: January 23, 2014Inventors: Matteo Montorfano, Alaide Chieffo, Juan F. Granada
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Patent number: 8398662Abstract: The present invention provides a valvuloplasty catheter which has a scoring element at its distal part to score stenotic, calcified heart valves in radial direction and to make the single valve flaps/leaflets work again. In addition to this, the device could comprise an attached balloon to post-dilate the valve after the scoring procedure. To reduce a future recalcification, the scoring element and/or the balloon have a pharmacologic coating on their outer surface.Type: GrantFiled: June 4, 2009Date of Patent: March 19, 2013Assignee: Bavaria Medizin Technologie GmbHInventors: Juan F. Granada, Knut Sauerteig
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Patent number: 8317857Abstract: Disclosed herein is a biodegradable prosthesis that includes a first end, a second end, and an elongate tubular body with a lumen therethrough. The prosthesis can have a first layer comprising a set of flexible interbraided bioabsorbable filaments, and optionally a set of flexible interbraided metallic filaments. Also, the prosthesis can have a second layer comprising a porous thermoplastic material that can be either an outer layer or an inner layer relative to the first layer. The prosthesis can include other features including branch apertures, folded portions, and attachment mechanisms for the first and second layers.Type: GrantFiled: July 15, 2009Date of Patent: November 27, 2012Assignee: Telesis Research, LLCInventors: Mehrdad Mike Shokoohi, Juan F. Granada
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Publication number: 20100016940Abstract: Disclosed herein is a biodegradable prosthesis that includes a first end, a second end, and an elongate tubular body with a lumen therethrough. The prosthesis can have a first layer comprising a set of flexible interbraided bioabsorbable filaments, and optionally a set of flexible interbraided metallic filaments. Also, the prosthesis can have a second layer comprising a porous thermoplastic material that can be either an outer layer or an inner layer relative to the first layer. The prosthesis can include other features including branch apertures, folded portions, and attachment mechanisms for the first and second layers.Type: ApplicationFiled: July 15, 2009Publication date: January 21, 2010Applicant: Telesis Research, LLCInventors: Mehrdad Mike Shokoohi, Juan F. Granada
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Publication number: 20090306582Abstract: The present invention provides a valvuloplasty catheter which has a scoring element at its distal part to score stenotic, calcified heart valves in radial direction and to make the single valve flaps/leaflets work again. In addition to this, the device could comprise an attached balloon to post-dilate the valve after the scoring procedure. To reduce a future recalcification, the scoring element and/or the balloon have a pharmacologic coating on their outer surface.Type: ApplicationFiled: June 4, 2009Publication date: December 10, 2009Applicant: BAVARIA MEDIZIN TECHNOLOGIE GMBHInventors: Juan F. Granada, Knut Sauerteig
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Patent number: 7396538Abstract: The present invention is an apparatus and a method for delivery of mitomycin through an eluting biocompatible implantable medical device. A biocompatible drug release matrix comprises a biocompatible drug release matrix and a drug incorporated into the biocompatible drug release matrix. The drug has antibiotic and anti-proliferative properties and is an analogue related to the quinone-containing alkylating agents of a mitomycin family. The drug is initially released from the biocompatible drug release matrix at a faster rate followed by a release at a slower rate. The drug release rate maintains tissue level concentrations of the drug for at least two weeks after implantation of the medical device. The present invention provides a coating for a vascular prosthesis that elutes the drug at a controlled rate to inhibit proliferation of smooth muscle cells causing restenosis.Type: GrantFiled: September 26, 2003Date of Patent: July 8, 2008Assignee: Endovascular Devices, Inc.Inventors: Juan F. Granada, Simon M. Furnish
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Publication number: 20080161908Abstract: The present invention is an apparatus and a method for delivery of mitomycin through an eluting biocompatible implantable medical device. A biocompatible drug release matrix comprises a biocompatible drug release matrix and a drug incorporated into the biocompatible drug release matrix. The drug has antibiotic and anti-proliferative properties and is an analogue related to the quinone-containing alkylating agents of a mitomycin family. The drug is initially released from the biocompatible drug release matrix at a faster rate followed by a release at a slower rate. The drug release rate maintains tissue level concentrations of the drug for at least two weeks after implantation of the medical device. The present invention provides a coating for a vascular prosthesis that elutes the drug at a controlled rate to inhibit proliferation of smooth muscle cells causing restenosis.Type: ApplicationFiled: March 17, 2008Publication date: July 3, 2008Inventors: Juan F. Granada, Simon M. Furnish
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Publication number: 20040098118Abstract: The present invention is an apparatus and a method for delivery of mitomycin through an eluting biocompatible implantable medical device. A biocompatible drug release matrix comprises a biocompatible drug release matrix and a drug incorporated into the biocompatible drug release matrix. The drug has antibiotic and anti-proliferative properties and is an analogue related to the quinone-containing alkylating agents of a mitomycin family. The drug is initially released from the biocompatible drug release matrix at a faster rate followed by a release at a slower rate. The drug release rate maintains tissue level concentrations of the drug for at least two weeks after implantation of the medical device. The present invention provides a coating for a vascular prosthesis that elutes the drug at a controlled rate to inhibit proliferation of smooth muscle cells causing restenosis.Type: ApplicationFiled: September 26, 2003Publication date: May 20, 2004Applicant: Endovascular Devices, Inc.Inventors: Juan F. Granada, Simon M. Furnish