Patents by Inventor Juan Iovanna

Juan Iovanna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions useful in the diagnostic of latently infected
    Patent number: 11448656
    Abstract: The present invention concerns a composition comprising at least three peptides derived from Mycobacterium tuberculosis antigen Rv2626c, its use in the diagnostic of latently infected Mycobacterium tuberculosis (LTBI) subjects, corresponding methods of use and kits.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: September 20, 2022
    Assignees: CNRS, CONICET, INSTITUT JEAN PAOLI & IRENE CALMETES, UNIVERSITE D' AIX-MARSEILLE, INSERM
    Inventors: Juan Iovanna, Virginia Pasquinelli, Maria Madgalena Gherardi, Hector Eduardo Chuluyan, Ana Inès Rovetta, Delfina Pena, Véronica Edith Garcia
  • NUPR1 INHIBITION FOR TREATING CANCER
    Publication number: 20210137938
    Abstract: The present invention relates to the treatment of a tumor selected from the group consisting of pancreatic cancer, liver cancer, melanoma, colon cancer, glioblastoma, osteosarcoma, prostate cancer and breast cancer, more particularly pancreatic cancer. The inventors found a novel family compounds of formula (I) able to treat a variety of cancers by inhibiting NUPR1, a stress-inducible 82-amino-acid-long, intrinsically disordered member of the AT-hook family of chromatin proteins. Thus, the present invention relates to a compound of formula (I) for its use in the treatment of a tumor selected from the group consisting of pancreatic cancer, liver cancer, melanoma, colon cancer, glioblastoma, osteosarcoma, prostate cancer and breast cancer. In particular, the inventors tested compounds of formula (I) on four well characterized primary pancreatic cancer-derived cells 02.
    Type: Application
    Filed: May 31, 2019
    Publication date: May 13, 2021
    Inventors: Olga ABIAN FRANCO, Patricia SANTOFIMIA, Yi XIA, Jose Luis NEIRA, Bruno RIZZUTI, Adrian VELAZQUEZ CAMPOY, Ling PENG, Juan IOVANNA
  • COMPOSITIONS USEFUL IN THE DIAGNOSTIC OF LATENTLY INFECTED MYCOBACTERIUM TUBERCULOSIS
    Publication number: 20180328948
    Abstract: The present invention concerns a composition comprising at least three peptides derived from Mycobacterium tuberculosis antigen Rv2626c, its use in the diagnostic of latently infected Mycobacterium tuberculosis (LTBI) subjects, corresponding methods of use and kits.
    Type: Application
    Filed: July 17, 2018
    Publication date: November 15, 2018
    Inventors: Juan IOVANNA, Virginia PASQUINELLI, Maria Madgalena GHERARDI, Hector Eduardo CHULUYAN, Ana Inès ROVETTA, Delfina PENA, Véronica Edith GARCIA
  • Compositions useful in the diagnostic of latently infected
    Patent number: 10067147
    Abstract: The present invention concerns a composition comprising at least three peptides derived from Mycobacterium tuberculosis antigen Rv2626c, its use in the diagnostic of latently infected Mycobacterium tuberculosis (LTBI) subjects, corresponding methods of use and kits.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: September 4, 2018
    Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Conicet (Consejo Nacional de Investigaciones Cientificas y Tecnicas, Institut Jean Paoli & Irene Calmettes, Universite d'Aix-Marseille, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Juan Iovanna, Virginia Pasquinelli, Maria Madgalena Gherardi, Hector Eduardo Chuluyan, Ana Inès Rovetta, Delfina Pena, Véronica Edith Garcia
  • COMPOSITIONS USEFUL IN THE DIAGNOSTIC OF LATENTLY INFECTED MYCOBACTERIUM TUBERCULOSIS
    Publication number: 20170242038
    Abstract: The present invention concerns a composition comprising at least three peptides derived from Mycobacterium tuberculosis antigen Rv2626c, its use in the diagnostic of latently infected Mycobacterium tuberculosis (LTBI) subjects, corresponding methods of use and kits.
    Type: Application
    Filed: August 28, 2015
    Publication date: August 24, 2017
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), CONICET (CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS), INSTITUT JEAN PAOLI & IRENE CALMETTES, UNIVERSITÉ D'AIX-MARSEILLE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Juan IOVANNA, Virginia PASQUINELLI, Maria Madgalena GHERARDI, Hector Eduardo CHULUYAN, Ana Inès ROVETTA, Delfina PENA, Véronica Edith GARCIA
  • METHOD AND PHARMACEUTICAL COMPOSITION FOR INHIBITING NEURONAL REMODELING
    Publication number: 20160312220
    Abstract: The present disclosure relates to a compound which inhibits the binding of SLIT2 to ROBO or ROB02 or a compound which is an inhibitor of SLIT2, ROBO1 or ROB02 gene expression for use as an inhibitor of the neuronal remodeling in cancer.
    Type: Application
    Filed: December 10, 2014
    Publication date: October 27, 2016
    Inventors: Richard TOMASINI, Juan IOVANNA, Véronique SECQ
  • Triazole derivatives, their preparation and their application in therapeutics
    Patent number: 8563526
    Abstract: The present invention relates to novel compounds of formula (A): in the form of a free base or of an addition salt with an acid. The invention also relates to process of preparation of compounds of formula (A), to composition comprising them and to their application in therapeutics and in particular in cancers.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: October 22, 2013
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Ling Peng, Palma Rocchi, Juan Iovanna, Yi Xia, Fanqi Qu, Jinqiao Wan, Yang Liu, Menghua Wang
  • NOVEL TRIAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS
    Publication number: 20110136754
    Abstract: The present invention relates to novel compounds of formula (A): in the form of a free base or of an addition salt with an acid. The invention also relates to process of preparation of compounds of formula (A), to composition comprising them and to their application in therapeutics and in particular in cancers.
    Type: Application
    Filed: April 29, 2009
    Publication date: June 9, 2011
    Inventors: Ling Peng, Palma Rocchi, Juan Iovanna, Yi Xia, Fanqi Qu, Jinqiao Wan, Yang Liu, Menghua Wang
  • Use of inhibitors of expression or activity of p8/com1 for treating tumors
    Publication number: 20040198679
    Abstract: The invention relates to the use of inhibitors of expression or activity of p8/com1 for treating tumours.
    Type: Application
    Filed: April 21, 2004
    Publication date: October 7, 2004
    Inventors: Sophie Vasseur, Juan Iovanna, Jean-Charles Dagorn