Patents by Inventor Juan José Lasarte Sagastibelza

Juan José Lasarte Sagastibelza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel T-Helper Antigenic Determinant (THD) Peptides
    Publication number: 20090220533
    Abstract: The invention relates to a chimeric peptide, which can bind to at least one allelic form of the HLA-DR molecule. The invention also relates to a pharmaceutical composition containing said peptide, as well as to the different uses of same.
    Type: Application
    Filed: December 19, 2006
    Publication date: September 3, 2009
    Inventors: Francisco Borras Cuesta, Juan Jose Lasarte Sagastibelza, Marta Ruiz Egozcue, Pablo Sarobe Ugarriza
  • Agents and methods based on the use of the eda domian of fibronectin
    Publication number: 20090220532
    Abstract: This invention relates to the use of a polypeptide in the production of an immunostimulatory agent, said polypeptide comprising a sequence corresponding to the EDA domain of fibronectin, a fragment of the EDA domain which can bind to TLR4 or a variant of said EDA domain or a fragment which can bind to TLR4 and which has a homology of more than 70% with any form or natural fragment of the EDA domain. The invention also relates to the production methods and applications of said agent.
    Type: Application
    Filed: June 13, 2006
    Publication date: September 3, 2009
    Inventors: Claude Leclerc, Juan Jose Lasarte Sagastibelza, Marta Gorraiz Ayala, Jesus Prieto Valtuena
  • TGF?1-inhibitor peptides
    Patent number: 7528226
    Abstract: Antagonistic synthetic peptides, obtained from TGF?1 or from its receptors in the organism, that can be used in the manufacture, both on their own, as well as the gene sequences that encode them and the recombinant systems that express them, in the manufacture of compositions for use in the treatment of liver diseases and more concretely in cases of fibrosis. The said compositions can optionally include mimotopes of the said active peptides.
    Type: Grant
    Filed: April 11, 2006
    Date of Patent: May 5, 2009
    Assignee: Rojecto de Biomedicina Cima S.L.
    Inventors: Ignacio José Ezquerro Saenz, Juan José Lasarte Sagastibelza, Jesús Prieto Valtueña, Francisco Borras Cuesta
  • TGF?1 inhibitor peptides
    Patent number: 7057013
    Abstract: Antagonistic synthetic peptides, obtained from TGF?1 or from its receptors in the organism, that can be used in the manufacture, both on their own, as well as the gene sequences that encode them and the recombinant systems that express them, in the manufacture of compositions for use in the treatment of liver diseases and more concretely in cases of fibrosis. The said compositions can optionally include mimotopes of the said active peptides.
    Type: Grant
    Filed: November 23, 1999
    Date of Patent: June 6, 2006
    Assignee: Proyecto de Biomedicina Cima, S.L.
    Inventors: Ignacio José Ezquerro Saenz, Juan José Lasarte Sagastibelza, Jesús Prieto Valtue{overscore (n)}a, Francisco Borras Cuesta
  • Use of cardiotrophin in liver diseases
    Publication number: 20040224888
    Abstract: Use of cardiotrophin in liver diseases. The invention describes the increased expression of cardiotrophin (CT-1) during the process of hepatic regeneration coinciding with maximum proliferation of hepatocytes and the role of CT-1 as a stimulator of hepatic regeneration. Furthermore, it describes the hepatoprotective role of CT-1 in various models of acute liver damage.
    Type: Application
    Filed: March 11, 2004
    Publication date: November 11, 2004
    Applicant: FUNDACION PARA LA INVESTIGACION MEDICA APLICADA
    Inventors: Matilde Bustos De Abajo, Jesus Prieto Valtuena, Juan Jose Lasarte Sagastibelza, Elena Baixeras Llano