Patents by Inventor Juan Pablo Giraldo Gomez

Juan Pablo Giraldo Gomez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230313217
    Abstract: Certain embodiments provide a polypeptide comprising a chloroplast-targeting amino acid sequence linked to an amino acid sequence that is capable of electrostatically binding to a nucleic acid molecule, as well as conjugates comprising such polypeptides and methods of use thereof.
    Type: Application
    Filed: November 28, 2022
    Publication date: October 5, 2023
    Inventors: Juan Pablo Giraldo Gomez, Israel Santana, Gregory Newkirk
  • Patent number: 11208628
    Abstract: In one aspect, a composition can include an organelle, and a nanoparticle having a zeta potential of less than ?10 mV or greater than 10 mV contained within the organelle. In a preferred embodiment, the organelle can be a chloroplast and the nanoparticle can be a single-walled carbon nanotube associated with a strongly anionic or strongly cationic polymer.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: December 28, 2021
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Michael S. Strano, Juan Pablo Giraldo Gomez, Sean Mitchell Faltermeier, Markita P. Landry
  • Patent number: 11186845
    Abstract: Compositions for chemical and/or genetic modification of chloroplasts of plants include a functionalized nanoparticle composition linked to a chloroplast-targeting peptide and a functionalized single walled carbon nanotube (SWNT) composition complexed with a nucleic acid cassette encoding a plastid-specific ribosomal RNA operon (prrn). Methods for chemically and/or genetically modifying chloroplasts of plants include administering these chloroplast-targeted compositions to the leaves of live plants.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: November 30, 2021
    Assignee: The Regents of the University of California
    Inventors: Juan Pablo Giraldo Gomez, Peiguang Hu, Israel Santana, Gregory Newkirk, Honghong Wu
  • Patent number: 11187698
    Abstract: A living plant can function as self-powered auto-samplers and preconcentrators of an analyte within ambient groundwater, detectors of the analyte contained therein. For example, a pair of near infrared (IR) fluorescent sensors embedded within the mesophyll of the plant leaf can be used as detectors of the nitroaromatic molecules, with the first IR channel engineered through CoPhMoRe to recognize analyte via an IR fluorescent emission and the second IR channel including a functionalized nanostructure that acts as an invariant reference signal.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: November 30, 2021
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Michael S. Strano, Juan Pablo Giraldo Gomez, Seongyeon Kwak, Min Hao Wong
  • Patent number: 11002741
    Abstract: A single chirality single walled carbon nanotubes (SWNT), and combinations thereof, can be used to detect trace levels of chemical compounds in vivo with high selectivity.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: May 11, 2021
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Juan Pablo Giraldo Gomez, Markita Patricia Landry, Michael S. Strano
  • Patent number: 10798938
    Abstract: A nanobionic approach for augmenting plant photoprotection and photosynthetic light energy conversion and carbon assimilation under abiotic (e.g., light) stress was used. Cerium oxide nanoparticles (nanoceria) improve Arabidopsis maximum quantum yield of photosystem II (10%) and carbon assimilation (19%) by protecting leaf mesophyll chloroplasts from damaging reactive oxygen species (ROS). Nanoceria augments scavenging of superoxide and hydroxyl radicals. For the latter, there are not known scavenging enzymatic pathways.
    Type: Grant
    Filed: June 22, 2017
    Date of Patent: October 13, 2020
    Assignee: The Regents of the University of California
    Inventors: Juan Pablo Giraldo Gomez, Honghong Wu, Nicholas Tito
  • Publication number: 20180356404
    Abstract: A living plant can function as self-powered auto-samplers and preconcentrators of an analyte within ambient groundwater, detectors of the analyte contained therein. For example, a pair of near infrared (IR) fluorescent sensors embedded within the mesophyll of the plant leaf can be used as detectors of the nitroaromatic molecules, with the first IR channel engineered through CoPhMoRe to recognize analyte via an IR fluorescent emission and the second IR channel including a functionalized nanostructure that acts as an invariant reference signal.
    Type: Application
    Filed: December 2, 2016
    Publication date: December 13, 2018
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Michael S. STRANO, Juan Pablo GIRALDO GOMEZ, Seongyeon KWAK, Min Hao WONG
  • Publication number: 20180317415
    Abstract: A plant nanobionic approach can utilize a system of four nanoparticle types, including luciferase conjugated silica, luciferin releasing poly(lactic-co-glycolic acid), coenzyme A functionalized chitosan, and semiconductor nanocrystal phosphors for wavelength modulation.
    Type: Application
    Filed: November 4, 2016
    Publication date: November 8, 2018
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Michael S. STRANO, Seongyeon KWAK, Juan Pablo Giraldo GOMEZ, Min Hao WONG
  • Publication number: 20170367325
    Abstract: A nanobionic approach for augmenting plant photoprotection and photosynthetic light energy conversion and carbon assimilation under abiotic (e.g., light) stress was used. Cerium oxide nanoparticles (nanoceria) improve Arabidopsis maximum quantum yield of photosystem II (10%) and carbon assimilation (19%) by protecting leaf mesophyll chloroplasts from damaging reactive oxygen species (ROS). Nanoceria augments scavenging of superoxide and hydroxyl radicals. For the latter, there are not known scavenging enzymatic pathways.
    Type: Application
    Filed: June 22, 2017
    Publication date: December 28, 2017
    Inventors: Juan Pablo Giraldo Gomez, Honghong Wu, Nicholas Tito
  • Publication number: 20170299601
    Abstract: A single chirality single walled carbon nanotubes (SWNT), and combinations thereof, can be used to detect trace levels of chemical compounds in vivo with high selectivity.
    Type: Application
    Filed: September 18, 2015
    Publication date: October 19, 2017
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Juan Pablo Giraldo Gomez, Markita Patricia Landry, Michael S. Strano
  • Publication number: 20150047074
    Abstract: In one aspect, a composition can include an organelle, and a nanoparticle having a zeta potential of less than ?10 mV or greater than 10 mV contained within the organelle. In a preferred embodiment, the organelle can be a chloroplast and the nanoparticle can be a single-walled carbon nanotube associated with a strongly anionic or strongly cationic polymer.
    Type: Application
    Filed: August 7, 2014
    Publication date: February 12, 2015
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Michael S. Strano, Juan Pablo Giraldo Gomez, Sean Mitchell Faltermeier, Markita P. Landry