Abstract: Embodiments of a method and/or system (e.g., for improved single molecule sequencing, etc.) can include preparing a set of unique molecular identifier (UMI)-based molecules associated with a set of target nucleic acid sequences; facilitating generation of (e.g., generating, etc.) a set of tagged nucleic acid molecules based on the set of UMI-based molecules and a set of nucleic acid molecules corresponding to (e.g., including, etc.) the set of target nucleic acid sequences; and/or facilitating (e.g., performing, etc.) single molecule sequencing with the set of tagged nucleic acid molecules.

Abstract: A system and method are disclosed for orchestrating the execution of computing tasks. An orchestration engine can receive task requests over a network from a plurality of process engines. The process engines may correspond to respective edge or field devices that are remotely located as compared to the orchestration engine. Each task request may indicate at least one task requirement for executing a respective computing task. A plurality of computing instances that have available computing resources can be selected from a set of computing instances. A predicted runtime can be generated for each of the computing tasks. In an example, based on the predicted runtimes, task requirements, available computing resources, and associated network conditions, a schedule and allocation scheme are determined by the orchestration engine.

Abstract: Embodiments of a method and/or system for characterizing one or more female reproductive system-related conditions can include determining a microorganism dataset associated with a set of subjects; and/or performing a characterization process associated with the one or more female reproductive system-related conditions, based on the microorganism dataset, where performing the characterization process can additionally or alternatively include performing a female reproductive system-related characterization process for the one or more female reproductive system-related conditions, and/or determining one or more therapies.

Abstract: Embodiments of a method and system for microbial pharmacogenomics can include: a sample handling system operable to collect containers including biological samples from a set of users, the handling system including a sequencing system operable to determine microorganism sequences from the biological samples; a microbiome characterization system operable to: determine microbiome pharmacogenomics data based on the microorganism sequences, collect supplementary data associated with the antibiotics-associated condition for the set of users, and transform the supplementary data and features extracted from the microbiome pharmacogenomics data into a characterization model associated with the antibiotics-associated condition; and a treatment system operable to promote a treatment to the user for the antibiotics-associated condition based on characterizing user biological material with the characterization model in relation to the antibiotics-associated condition.

Abstract: Embodiments of a method and/or system (e.g., for improved single molecule sequencing, etc.) can include preparing a set of unique molecular identifier (UMI)-based molecules associated with a set of target nucleic acid sequences; facilitating generation of (e.g., generating, etc.) a set of tagged nucleic acid molecules based on the set of UMI-based molecules and a set of nucleic acid molecules corresponding to (e.g., including, etc.) the set of target nucleic acid sequences; and/or facilitating (e.g., performing, etc.) single molecule sequencing with the set of tagged nucleic acid molecules.

Abstract: Embodiments of a method and/or system (e.g., for nasal-related characterization) can include determining a microorganism dataset associated with a set of subjects; and/or performing a characterization process based on the microorganism dataset, where performing the characterization process can additionally or alternatively include performing a nasal-related characterization process, and/or determining one or more therapies, such as for one or more nasal-related conditions.

Abstract: Embodiments of a method and/or system (e.g., for improved single molecule sequencing, etc.) can include preparing a set of unique molecular identifier (UMI)-based molecules associated with a set of target nucleic acid sequences; facilitating generation of (e.g., generating, etc.) a set of tagged nucleic acid molecules based on the set of UMI-based molecules and a set of nucleic acid molecules corresponding to (e.g., including, etc.) the set of target nucleic acid sequences; and/or facilitating (e.g., performing, etc.) single molecule sequencing with the set of tagged nucleic acid molecules.

Abstract: Embodiments of a method and/or system for characterizing one or more female reproductive system-related conditions can include determining a microorganism dataset associated with a set of subjects; and/or performing a characterization process associated with the one or more female reproductive system-related conditions, based on the microorganism dataset, where performing the characterization process can additionally or alternatively include performing a female reproductive system-related characterization process for the one or more female reproductive system-related conditions, and/or determining one or more therapies.

Abstract: Embodiments of a method and/or system (e.g., for nasal-related characterization) can include determining a microorganism dataset associated with a set of subjects; and/or performing a characterization process based on the microorganism dataset, where performing the characterization process can additionally or alternatively include performing a nasal-related characterization process, and/or determining one or more therapies, such as for one or more nasal-related conditions.

Abstract: Embodiments of a method and system for microbial pharmacogenomics can include: a sample handling system operable to collect containers including biological samples from a set of users, the handling system including a sequencing system operable to determine microorganism sequences from the biological samples; a microbiome characterization system operable to: determine microbiome pharmacogenomics data based on the microorganism sequences, collect supplementary data associated with the antibiotics-associated condition for the set of users, and transform the supplementary data and features extracted from the microbiome pharmacogenomics data into a characterization model associated with the antibiotics-associated condition; and a treatment system operable to promote a treatment to the user for the antibiotics-associated condition based on characterizing user biological material with the characterization model in relation to the antibiotics-associated condition.

Abstract: The present invention makes known an array of nucleotidic sequences for rapidly and simultaneously identifying the presence of certain genes that codify proteins with relevant activities in biotechnology present in a microbiological sample, and the method with which this array is used in the identification of the above mentioned genes. Specifically speaking, genes that codify for proteins relevant in the biofilm formation, in CO2 fixation, in energetic metabolism, for chemiotaxis and mobility, in iron oxidizing, in nitrogen metabolism, in sulfur assimilation, and in oxidation/reduction of sulphide compounds, are identified. This array of nucleotidic sequences is presented as a useful tool in biotechnology whenever evaluating the quality of a microbiological community is required.

Abstract: The present invention makes known an array of nucleotididc sequences for rapidly and simultaneously identifying the presence of certain genes that codify proteins with activities relevant in biotechnology, present in a microbiological sample, and the method for using this array in the identification of the said genes. Specifically, genes that codify for proteins relevant in Biofilm formation, in CO2 fixation, in Energetic metabolism, for chemiotaxis and mobility, in iron oxidization, in nitrogen metabolism, in Sulfur assimilation, and in oxidation/reduction of sulfide compounds. This array of nucleotidic sequences is presented as a useful tool in biotechnology in all cases requiring an evaluation of the quality of a microbiological community.

Abstract: A Brucella bacterium is modified by partial or complete deletion of the pgm gene, rendering the bacterium incapable of synthesizing a key enzyme in the metabolism of bacterial sugars. A live vaccine for immunization, prophylaxis or treatment of brucellosis comprises such a bacterium, either lyophilized or in a pharmaceutical vehicle. Nucleotide sequence fragments having the aforementioned deletion are disclosed, with methods for making them.