Abstract: The present disclosure generally relates to a personalized cancer vaccine having attenuated cancer cells transfected with at least one expression construct. The expression construct is capable of secretory expression of an antigenic polypeptide that could be derived from a protein from a virus. The personalized tumor vaccine, when administered to a subject in need thereof, is effective to activate an immune response.

Abstract: Disclosed is a fundus image quality evaluation method based on multi-source and multi-scale feature fusion, comprising following steps: S1, acquiring multi-source fundus images, labeling the multi-source fundus images with four evaluation dimensions of brightness, blur, contrast and overall image quality, and forming training samples with the fundus image and labeling labels; S2, constructing a fundus image quality evaluation network including a feature extraction module, a fusion module, an attention module and an evaluation module; S3, training the fundus image quality evaluation network by using training samples to obtain a fundus image quality evaluation model; and S4: inputting fundus images to be measured into the fundus image quality evaluation model, and outputting quality evaluation results through calculation. Also provided is a fundus image quality evaluation device based on above method.

Abstract: Disclosed is a fundus image quality evaluation method based on multi-source and multi-scale feature fusion, comprising following steps: S1, acquiring multi-source fundus images, labeling the multi-source fundus images with four evaluation dimensions of brightness, blur, contrast and overall image quality, and forming training samples with the fundus image and labeling labels; S2, constructing a fundus image quality evaluation network including a feature extraction module, a fusion module, an attention module and an evaluation module; S3, training the fundus image quality evaluation network by using training samples to obtain a fundus image quality evaluation model; and S4: inputting fundus images to be measured into the fundus image quality evaluation model, and outputting quality evaluation results through calculation. Also provided is a fundus image quality evaluation device based on above method.

Abstract: A disposable tourniquet comprising a buckle and a band attached at one end to the buckle, the buckle comprising a base into which the band can be laid and a laterally hinged clamp closure that can be closed over the band to grip it in the buckle and a hinged closure securing tab.

Abstract: A disposable tourniquet comprising a buckle and a band attached at one end to the buckle, the buckle comprising a base into which the band can be laid and a laterally hinged clamp closure that can be closed over the band to grip it in the buckle and a hinged closure securing tab.

Abstract: An improved capacitor is described. The capacitor has an anode with an anode lead wire extending from a first face of the anode. A dielectric layer is on the anode and a cathode is on the dielectric. An anode lead with an anode base and a cavernous anode protrusion extending from the base is provided wherein the anode lead wire is in electrical contact with the anode protrusion. A cathode lead with a cathode base is provided wherein the cathode base is in electrical contact with the cathode on a side face wherein the side face is adjacent the first face and the cathode base and said anode base are coplanar.

Abstract: An improved capacitor is described. The capacitor has an anode with an anode lead wire extending from a first face of the anode. A dielectric layer is on the anode and a cathode is on the dielectric. An anode lead with an anode base and a cavernous anode protrusion extending from the base is provided wherein the anode lead wire is in electrical contact with the anode protrusion. A cathode lead with a cathode base is provided wherein the cathode base is in electrical contact with the cathode on a side face wherein the side face is adjacent the first face and the cathode base and said anode base are coplanar.